Zobrazeno 1 - 10
of 318
pro vyhledávání: '"S, Zaher"'
Autor:
Alana R Plastrik, Hani S Zaher
Publikováno v:
PLoS Biology, Vol 22, Iss 12, p e3002925 (2024)
In eukaryotes, defective mRNAs that impede the movement of the ribosome are subject to rapid decay via no-go decay (NGD). In this issue of PLOS Biology, Ishibashi and colleagues expand on the role of NGD and reveal new endogenous targets for the proc
Externí odkaz:
https://doaj.org/article/cb1d59c1671f4e6f8362c06668041216
Autor:
Jenna C. McGuffey, Clay D. Jackson-Litteken, Gisela Di Venanzio, Aubree A. Zimmer, Jessica M. Lewis, Jesus S. Distel, Kyusik Q. Kim, Hani S. Zaher, Juan Alfonzo, Nichollas E. Scott, Mario F. Feldman
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Successful pathogens must be able to adapt to a multitude of stressors imposed by their host. Acinetobacter baumannii has emerged as a major global health threat due to its exceptional ability to adapt to hostile environments and skyrocketin
Externí odkaz:
https://doaj.org/article/36fb02e91a4f408baf97b05f436e762d
Autor:
T Minto, MBChB, T Abdelrahman, MD, L Jones, MBA, J Wheat, FRCS, T Key, MBChB, N Shivakumar, MBChB, J Ansell, MD, O Seddon, MBBCh, A Cronin, FRCS, A Tomkinson, FRCS, A Theron, FRCA, RW Trickett, MD, N Sagua, S Sultana, A Clark, E McKay, A Johnson, Karishma Behera, J Towler, H Kynaston, MD, A Mohamed, G Blackshaw, R Thomas, S Jones, M Shinkwin, H Perry, D Edgbeare, S Chopra, L DaSilva, I Williams, U Contractor, S Bell, S Zaher, M Stechman, S Berry, H Clark, E Bois, C Von Oppell, L Ackerman, E Ablorsu, J Horwood, D Mehta, J Featherstone, E Folaranmi, M Bray, K Siddall, E King, M Phillips, J Morgan, I Chopra, D Evans, K Whitehouse, P Leach, C Thomas, E Davies, M Dyer, A Fox, E Ireland, E Meehan, A Mukit, K Newell, D Parry, B Popham, C Chapman, H Botros
Publikováno v:
Surgery Open Science, Vol 10, Iss , Pp 168-173 (2022)
Background: The COVID-19 pandemic has caused unprecedented health care challenges mandating surgical service reconfiguration. Within our hospital, emergency and elective streams were separated and self-contained Protected Elective Surgical Units were
Externí odkaz:
https://doaj.org/article/d70330ee25f143e3b9db9a439dd39349
Expansion of a novel population of NK cells with low ribosome expression in juvenile dermatomyositis
Autor:
Kinsey A. Hilliard, Allison A. Throm, Jeanette T. Pingel, Nermina Saucier, Hani S. Zaher, Anthony R. French
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Juvenile dermatomyositis (JDM) is a pediatric autoimmune disease associated with characteristic rash and proximal muscle weakness. To gain insight into differential lymphocyte gene expression in JDM, peripheral blood mononuclear cells from 4 new-onse
Externí odkaz:
https://doaj.org/article/5cfde86b4f994b67903261c7dc84a4bb
Publikováno v:
Egyptian Journal of Aquatic Research, Vol 47, Iss 3, Pp 293-300 (2021)
Qarun Lake is a unique saline basin. Its phytoplankton species abundance and dynamics in relation to the Red Tide phenomenon is the focus of this study. Samples were collected from May 2015 to April 2016 in twelve successive cruises. Phytoplankton pr
Externí odkaz:
https://doaj.org/article/b43e9fe413434a36b57b6d48a63c73b4
Autor:
Claudia Lancey, Muhammad Tehseen, Vlad-Stefan Raducanu, Fahad Rashid, Nekane Merino, Timothy J. Ragan, Christos G. Savva, Manal S. Zaher, Afnan Shirbini, Francisco J. Blanco, Samir M. Hamdan, Alfredo De Biasio
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Pol δ bound to the proliferating cell nuclear antigen (PCNA) replicates the lagging strand in eukaryotes and cooperates with flap endonuclease 1 (FEN1) to process the Okazaki fragments for their ligation. Here, the authors present a Cryo-EM structur
Externí odkaz:
https://doaj.org/article/782ada8b374241e2b47934138793c3f7
Autor:
Braulio Bonilla, Alexander J Brown, Sarah R Hengel, Kyle S Rapchak, Debra Mitchell, Catherine A Pressimone, Adeola A Fagunloye, Thong T Luong, Reagan A Russell, Rudri K Vyas, Tony M Mertz, Hani S Zaher, Nima Mosammaparast, Ewa P Malc, Piotr A Mieczkowski, Steven A Roberts, Kara A Bernstein
Publikováno v:
eLife, Vol 10 (2021)
Three-methyl cytosine (3meC) are toxic DNA lesions, blocking base pairing. Bacteria and humans express members of the AlkB enzymes family, which directly remove 3meC. However, other organisms, including budding yeast, lack this class of enzymes. It r
Externí odkaz:
https://doaj.org/article/3c12084a8dba4d91b827c88a4ddb1f77
Autor:
Manasvi Verma, Junhong Choi, Kyle A. Cottrell, Zeno Lavagnino, Erica N. Thomas, Slavica Pavlovic-Djuranovic, Pawel Szczesny, David W. Piston, Hani S. Zaher, Joseph D. Puglisi, Sergej Djuranovic
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Several factors contribute to the efficiency of protein expression. Here the authors show that the identity of amino acids encoded by codons at position 3–5 significantly impact translation efficiency and protein expression levels.
Externí odkaz:
https://doaj.org/article/d6c7739bcd3d4753818faecc0bc65dc2
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The mRNA-surveillance pathway of no-go decay (NGD) is a eukaryotic ribosome-based-quality-control process that targets transcripts that stall the ribosome. Here the authors show no-go decay (NGD) and ribosome-quality control (RQC) pathways are activa
Externí odkaz:
https://doaj.org/article/4bdc7027d15d45759a4f1b0de623dfef
Autor:
Vanessa Oliveira, Nitin Mahajan, Melissa L. Bates, Chakrapani Tripathi, Kyusik Q. Kim, Hani S. Zaher, Leonard B. Maggi Jr, Michael H. Tomasson
Publikováno v:
FASEB BioAdvances, Vol 1, Iss 7, Pp 404-414 (2019)
Abstract The orphan small nucleolar RNA (snoRNA) ACA11 is overexpressed as a result of the t(4;14) chromosomal translocation in multiple myeloma (MM), increases reactive oxygen species, and drives cell proliferation. Like other snoRNAs, ACA11 is pred
Externí odkaz:
https://doaj.org/article/2c20f4e656694a63b1229336ad7e548f