Výsledky vyhledávání - "S, Vukmanović"

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Akademický článek

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MHC Class I Is Required for Peripheral Accumulation of CD8+ Thymic Emigrants

Autor: D, Nesić, S, Vukmanović

Publikováno v: The Journal of Immunology. 160:3705-3712

MHC molecules influence the fate of T lymphocytes at two important stages of their differentiation. Recognition of self peptide/MHC complexes in the thymus determines whether immature T cells should live and mature into immunocompetent T cells or whe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d607ff169e96abe124de0dd34db7f4
https://doi.org/10.4049/jimmunol.160.8.3705

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The role of protein kinase C in CD8+ T lymphocyte effector responses

Autor: D Nesic, K G Jhaver, S Vukmanović

Publikováno v: The Journal of Immunology. 159:582-590

Rare CD8+ T cells present in beta2microglobulin-deficient (beta2m-/-) mice reject allogeneic tumors but not syngeneic wild-type tumors. The lack of syngeneic tumor rejection in vivo is correlated with a partial response of beta2m-/- CD8+ cell lines t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e4c7024b8d9e54c95c990529e09b890
https://doi.org/10.4049/jimmunol.159.2.582

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Apparent split tolerance of CD8+ T cells from beta 2-microglobulin-deficient (beta 2m-/-) mice to syngeneic beta 2m+/+ cells

Autor: K G Jhaver, T D Rao, A B Frey, S Vukmanović

Publikováno v: The Journal of Immunology. 154:6252-6261

beta 2-microglobulin-deficient (beta 2m-/-) mice express reduced levels of MHC class I molecules and, consequently, have impaired positive selection of CD8+ T lymphocytes in the thymus. However, small numbers of CD8+ CTLs can be found in beta 2m-/- m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c03200248ba1d4915e10489ae7b7105
https://doi.org/10.4049/jimmunol.154.12.6252

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Akademický článek

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CD8(+) T cell cytolytic activity independent of mitogen-activated protein kinase / extracellular regulatory kinase signaling (MAP kinase / ERK)

Autor: M, Lilić, K, Kulig, I, Messaoudi, K, Remus, M, Janković, J, Nikolić-Zugić, S, Vukmanović

Publikováno v: European journal of immunology. 29(12)

Cytotoxicity is a major effector function of CD8(+) T cells. Although mitogen-activated protein kinase (MAP kinase) / extracellular regulatory kinase (ERK) activity is indispensable for cytotoxic activity of most CD8(+) T cells a portion of CD8(+) T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4600aec437dd424ed85b5b8cab9b9db3
https://pubmed.ncbi.nlm.nih.gov/10602006

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Altered effector responses of H-Y transgenic CD8+ cells

Autor: I Arsov, S Vukmanović

Publikováno v: International immunology. 9(10)

The primary role of CD8+ T cells is to destroy virus-infected or tumor cells expressing cognate antigens in the form of peptide-MHC class I complexes. This destruction is primarily achieved by the actions of lytic mediators and/or lymphokines. In thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51face83387595000b46ea9073844f9
https://pubmed.ncbi.nlm.nih.gov/9352347

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Stimulation of CD8+ T cell responses to MAGE-3 and Melan A/MART-1 by immunization to a polyvalent melanoma vaccine

Autor: S R, Reynolds, R, Oratz, R L, Shapiro, P, Hao, Z, Yun, M, Fotino, S, Vukmanović, J C, Bystryn

Publikováno v: International journal of cancer. 72(6)

A critical requirement for cancer vaccines is that they stimulate CD8+ T cell responses. In this study, we tested the ability of a polyvalent melanoma vaccine to induce CD8+ T cell responses to the melanoma associated antigens MAGE-3 and Melan A/MART

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bbcb48e7791ef2e654986f257a633dc0
https://pubmed.ncbi.nlm.nih.gov/9378560

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A positively selecting thymic epithelial cell line lacks costimulatory activity

Autor: S, Vukmanović, G, Stella, P D, King, R, Dyall, K A, Hogquist, J T, Harty, J, Nikolić-Zugić, M J, Bevan

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 152(8)

The participation of costimulatory molecule interactions in positive selection of T lymphocytes was addressed by assessing the ability of a positively selecting thymic epithelial cell (TEC) line, 427.1, to stimulate allospecific CTL responses. Stimul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e5fe6952c77dfe52db8958dfa7de4763
https://pubmed.ncbi.nlm.nih.gov/7511660

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