Výsledky vyhledávání

Detection of methylation in the CpG islands of the p16INK4A, RASSF 1A and methylguanine methyltransferase gene promoters in pancreatic adenocarcinoma

Autor: P. Stravoravdi, I Stergiou, D. Paikos, P. Papakotoulas, A. Kiziridou, I Boukovinas, G. Sibilidis, S. Voyatzi

Publikováno v: ecancermedicalscience

Pancreatic cancer consists of an accumulation of genetic and epigenetic alterations. Recently, aberrant methylation of CpG islands of cancer-related genes has emerged as an important epigenetic mechanism of their transcriptional dysregulation during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b3697e8b1e41b3db2fb318cb9d30c2
https://pubmed.ncbi.nlm.nih.gov/22276000

Zobrazit plný text záznamu

Albumin possesses intrinsic enolase activity towards dihydrotestosterone which can differentiate benign from malignant breast tumors

Autor: Z, Drmanovic, S, Voyatzi, D, Kouretas, D, Sahpazidou, A, Papageorgiou, O, Antonoglou

Publikováno v: Anticancer research. 19(5B)

Serum albumin was found to possess enolase activity towards the dihydrotestesterone (DHT) molecule, converting it from its 3-keto to 3-enol form. This activity was accompanied by albumin during all stages of purification, as well as following various

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8c45dfa546252dc42744d64099899baf
https://pubmed.ncbi.nlm.nih.gov/10628362

Zobrazit plný text záznamu

Enzymatic conversion of dihydrotestosterone from 3-keto to 3-enol form in the rat prostate

Autor: D, Kouretas, S, Voyatzi, D, Sahpazidou, K, Lazopoulos, O, Antonoglou

Publikováno v: Anticancer research. 16(5A)

Dihydrotestosterone (DHT) is the active androgen, as well as a strong tumor promoter in the prostate, where several enzymes are essential for the regulation of its activity. We localized four enzymes promoting the enolization of the 3-keto group of D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::81de87e85df8be9b12ec64e5397c3b9a
https://pubmed.ncbi.nlm.nih.gov/8917395

Zobrazit plný text záznamu

Relation of methylation profiling between DNA repair gene MGMT and estrogen receptor alpha (ERα) gene in breast cancer (BC)

Autor: G. Zafiriou, D. Paikos, K. Desiris, G. Simbilidis, A. Kiziridou, S. Voyatzi, P. Stravoravdi, M. Markopoulos

Publikováno v: Journal of Clinical Oncology. 29:e13579-e13579

e13579 Background: The silencing of key cancer genes, via promoter methylation, affects molecular pathways involved in DNA repair and cell signaling. This epigenetic event is currently being invest...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f5b96d7c14cbcfd71add197b44b35e3a
https://doi.org/10.1200/jco.2011.29.15_suppl.e13579

Zobrazit plný text záznamu

Promoter methylation of p16INK4A, RASSF1A, and RAR2b genes in tumor DNA from patients with breast cancer (BC) in correlation with clinical recurrence

Autor: George D. Geromichalos, A. Kiziridou, E. Stergiou, D. Paikos, G. Simbilidis, P. Stravoravdi, K. Desiris, S. Voyatzi, K. Pazaitou

Publikováno v: Journal of Clinical Oncology. 28:1551-1551

1551 Background: Currently, no definite epigenetic markers exist to predict tumor recurrence after surgical resection in patients (pts) with BC. We studied the methylation pattern of 3 growth regulatory genes p16INK4A , RASSF1A and RAR2b in pts with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee7ba51b2edbb62c80d44ed595902f82
https://doi.org/10.1200/jco.2010.28.15_suppl.1551

Zobrazit plný text záznamu

Detection of methylation in the CpG islands of the RASSF1A and RAR2b gene promoters in breast cancer (BC)

Autor: P. Stravoravdi, K. Desiris, E. Stergiou, A. Kiziridou, G. Sibilidis, S. Voyatzi, I. Boukovinas, D. Paikos

Publikováno v: Journal of Clinical Oncology. 27:e14632-e14632

e14632 Background: Aberrant methylation of CpG islands of cancer-related genes has emerged as an important epigenetic mechanism during carcinogenesis. We examined the methylation of RASSF1A (Ras-association domain family 1, isoform A) and RAR2b (Reti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::28863915505b1053159a08051f2d9a4a
https://doi.org/10.1200/jco.2009.27.15_suppl.e14632

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání