Zobrazeno 1 - 10
of 7 905
pro vyhledávání: '"S, Vincent"'
Autor:
Matteo Giaccherini, Alyssa I. Clay-Gilmour, Romano Liotti, Angelica Macauda, Manuel Gentiluomo, Elizabeth E. Brown, Mitchell J. Machiela, Stephen J. Chanock, Michelle A. T. Hildebrandt, Aaron D. Norman, Elisabet Manasanch, S. Vincent Rajkumar, Jonathan N. Hofmann, Sonja I. Berndt, Parveen Bhatti, Graham G. Giles, Elad Ziv, Shaji K. Kumar, Nicola J. Camp, Wendy Cozen, Susan L. Slager, Federico Canzian, Federica Gemignani, Celine M. Vachon, Daniele Campa
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/80466d49fbbd467887abb1da0f10e198
Autor:
Spencer I. Danto, Nikolaos Tsamandouras, Padma Reddy, Steven A. Gilbert, Jessica Y. Mancuso, Karen Page, Jean S. Beebe, Elena Peeva, Michael S. Vincent
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 20, Iss 1, Pp 1-8 (2024)
Abstract PF-06817024 is a humanized antibody against interleukin-33 that has the potential to inhibit type 2 inflammation. An exploratory analysis of the pharmacodynamics and clinical effects of single and repeat doses of PF-06817024 was assessed in
Externí odkaz:
https://doaj.org/article/342daf6733c54dea9222dbbb5a9d74c3
Autor:
Charlotte Pawlyn, Fredrik H. Schjesvold, David A. Cairns, L. J. Wei, Faith Davies, Omar Nadeem, Haifaa Abdulhaq, Maria-Victoria Mateos, Jacob Laubach, Katja Weisel, Heinz Ludwig, S. Vincent Rajkumar, Pieter Sonneveld, Graham Jackson, Gareth Morgan, Paul G. Richardson
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Measurement of overall survival (OS) remains the gold standard for interpreting the impact of new therapies for multiple myeloma in phase 3 trials. However, as outcomes have improved, it is increasingly challenging to use OS as the primary e
Externí odkaz:
https://doaj.org/article/186d300a7c3d4b47adaec4bd25b20ac5
Autor:
Matthew J. Rees, Aytaj Mammadzadeh, Abiola Bolarinwa, Mohammed E. Elhaj, Arwa Bohra, Radhika Bansal, Sikander Ailawadhi, Ricardo Parrondo, Saurabh Chhabra, Amit Khot, Suzanne Hayman, Angela Dispenzieri, Francis Buadi, David Dingli, Rahma Warsame, Prashant Kapoor, Morie A. Gertz, Eli Muchtar, Taxiarchis Kourelis, Wilson Gonsalves, S. Vincent Rajkumar, Yi Lin, Shaji Kumar
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Three classes of BCMA-directed therapy (BDT) exist: antibody drug-conjugates (ADCs), CAR-T, and T-cell engagers (TCEs), each with distinct strengths and weaknesses. To aid clinicians in selecting between BDTs, we reviewed myeloma patients tr
Externí odkaz:
https://doaj.org/article/e937bbbd77af4514829023b80d8a83b4
Autor:
Stanley Cohen, Jean S. Beebe, Vishala Chindalore, Shunjie Guan, Mina Hassan-Zahraee, Madhurima Saxena, Li Xi, Craig Hyde, Sarita Koride, Robert Levin, Shannon Lubaczewski, Mikhail Salganik, Abigail Sloan, Erin Stevens, Elena Peeva, Michael S. Vincent, David A. Martin, Myron Chu
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-18 (2024)
Abstract Background The objective of this study was to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of PF‑06835375, a potent selective afucosyl immunoglobulin G1 antibody targeting C-X-C chemokine receptor type 5 (CXCR5
Externí odkaz:
https://doaj.org/article/de4e6e08230342d8a8ccd262c81c4143
Autor:
Dongliang Ma, Kun-Yang Lin, Divya Suresh, Jiaen Lin, Mahekta R Gujar, Htet Yamin Aung, Ye Sing Tan, Yang Gao, Anselm S Vincent, Teng Chen, Hongyan Wang
Publikováno v:
PLoS Biology, Vol 22, Iss 8, p e3002751 (2024)
ADP ribosylation factor-like GTPase 2 (Arl2) is crucial for controlling mitochondrial fusion and microtubule assembly in various organisms. Arl2 regulates the asymmetric division of neural stem cells in Drosophila via microtubule growth. However, the
Externí odkaz:
https://doaj.org/article/56b660e359b74bee9018a3cdc95d95ec
Autor:
Ghulam Rehman Mohyuddin, Samuel M. Rubinstein, Shaji Kumar, S. Vincent Rajkumar, Rafael Fonseca, Nadine H. Abdallah, Gregory S. Calip, Xiaoyan Wang, Christina M. Parrinello, Douglas Sborov
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/43494671ef6e40a28912afcb49e105cb
Autor:
Utkarsh Goel, Charalampos Charalampous, Prashant Kapoor, Moritz Binder, Francis K. Buadi, David Dingli, Angela Dispenzieri, Amie Fonder, Morie A. Gertz, Wilson I. Gonsalves, Suzanne R. Hayman, Miriam A. Hobbs, Yi L. Hwa, Taxiarchis Kourelis, Martha Q. Lacy, Nelson Leung, Yi Lin, Rahma M. Warsame, Robert A. Kyle, S. Vincent Rajkumar, Shaji K. Kumar
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-6 (2024)
Abstract Refractoriness to lenalidomide is an important factor determining the choice of therapy at first relapse in multiple myeloma (MM). It remains debatable if resistance to lenalidomide varies among MM refractory to standard doses vs low dose ma
Externí odkaz:
https://doaj.org/article/eba49be384594a6b9736e10c9aa74562
Autor:
Fieke W. Hoff, Rahul Banerjee, Adeel M. Khan, Georgia McCaughan, Bo Wang, Xiaoliang Wang, James Roose, Larry D. Anderson, Andrew J. Cowan, S. Vincent Rajkumar, Gurbakhash Kaur
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Induction regimens for multiple myeloma (MM) commonly include bortezomib, which has typically been administered twice weekly despite studies demonstrating comparable efficacy and less peripheral neuropathy (PN) with once-weekly bortezomib. W
Externí odkaz:
https://doaj.org/article/77e2c5dd5c1e465ab0a5f0129e367a86
Autor:
Nadine H. Abdallah, Arjun Lakshman, Shaji K. Kumar, Joselle Cook, Moritz Binder, Prashant Kapoor, Angela Dispenzieri, Morie A. Gertz, Martha Q. Lacy, Suzanne R. Hayman, Francis K. Buadi, David Dingli, Yi Lin, Taxiarchis Kourelis, Rahma Warsame, Leif Bergsagel, S. Vincent Rajkumar
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract The approach to patients with high-risk smoldering multiple myeloma (SMM) varies among clinicians; while some advocate early intervention, others reserve treatment at progression to multiple myeloma (MM). We aimed to describe the myeloma-def
Externí odkaz:
https://doaj.org/article/0c829e27d7424164a3db5cbae0cc8d91