Zobrazeno 1 - 10
of 1 925
pro vyhledávání: '"S, Tomlinson"'
Autor:
Ffion R Hammond, Amy Lewis, Gabriele Pollara, Gillian S Tomlinson, Mahdad Noursadeghi, Endre Kiss-Toth, Philip M Elks
Publikováno v:
eLife, Vol 13 (2024)
Tuberculosis is a major global health problem and is one of the top 10 causes of death worldwide. There is a pressing need for new treatments that circumvent emerging antibiotic resistance. Mycobacterium tuberculosis parasitises macrophages, reprogra
Externí odkaz:
https://doaj.org/article/bd3dd043b8a54eb0866c183d509594af
Autor:
Puja Mehta, Blanca Sanz-Magallón Duque de Estrada, Emma K. Denneny, Kane Foster, Carolin T. Turner, Andreas Mayer, Martina Milighetti, Manuela Platé, Kaylee B. Worlock, Masahiro Yoshida, Jeremy S. Brown, Marko Z. Nikolić, Benjamin M. Chain, Mahdad Noursadeghi, Rachel C. Chambers, Joanna C. Porter, Gillian S. Tomlinson
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPersistent radiological lung abnormalities are evident in many survivors of acute coronavirus disease 2019 (COVID-19). Consolidation and ground glass opacities are interpreted to indicate subacute inflammation whereas reticulation is though
Externí odkaz:
https://doaj.org/article/0c20d7c4f93849d0869626a0bd37c791
Autor:
E.M. Bassi, K.S. Bright, L.G. Norman, K. Pintson, S. Daniel, S. Sidhu, J. Gondziola, J. Bradley, M. Fersovitch, L. Stamp, K. Moskovic, H.M. LaMonica, F. Iorfino, T. Gaskell, S. Tomlinson, D.W. Johnson, G. Dimitropoulos
Publikováno v:
Digital Health, Vol 10 (2024)
Objectives Increased rates of mental health disorders and substance use among youth and young adults have increased globally, furthering the strain on an already burdened mental health system. Digital solutions have been proposed as a potential optio
Externí odkaz:
https://doaj.org/article/b0871eb8a5e945e19965706de3bf8b11
Autor:
Mary L. Stackpole, Weihua Zeng, Shuo Li, Chun-Chi Liu, Yonggang Zhou, Shanshan He, Angela Yeh, Ziye Wang, Fengzhu Sun, Qingjiao Li, Zuyang Yuan, Asli Yildirim, Pin-Jung Chen, Paul Winograd, Benjamin Tran, Yi-Te Lee, Paul Shize Li, Zorawar Noor, Megumi Yokomizo, Preeti Ahuja, Yazhen Zhu, Hsian-Rong Tseng, James S. Tomlinson, Edward Garon, Samuel French, Clara E. Magyar, Sarah Dry, Clara Lajonchere, Daniel Geschwind, Gina Choi, Sammy Saab, Frank Alber, Wing Hung Wong, Steven M. Dubinett, Denise R. Aberle, Vatche Agopian, Steven-Huy B. Han, Xiaohui Ni, Wenyuan Li, Xianghong Jasmine Zhou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/099e0ea22a6b40a8ad77bcf1133b06ef
Autor:
Mary L. Stackpole, Weihua Zeng, Shuo Li, Chun-Chi Liu, Yonggang Zhou, Shanshan He, Angela Yeh, Ziye Wang, Fengzhu Sun, Qingjiao Li, Zuyang Yuan, Asli Yildirim, Pin-Jung Chen, Paul Winograd, Benjamin Tran, Yi-Te Lee, Paul Shize Li, Zorawar Noor, Megumi Yokomizo, Preeti Ahuja, Yazhen Zhu, Hsian-Rong Tseng, James S. Tomlinson, Edward Garon, Samuel French, Clara E. Magyar, Sarah Dry, Clara Lajonchere, Daniel Geschwind, Gina Choi, Sammy Saab, Frank Alber, Wing Hung Wong, Steven M. Dubinett, Denise R. Aberle, Vatche Agopian, Steven-Huy B. Han, Xiaohui Ni, Wenyuan Li, Xianghong Jasmine Zhou
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Early cancer detection by cell-free DNA faces multiple challenges: low fraction of tumor cell-free DNA, molecular heterogeneity of cancer, and sample sizes that are not sufficient to reflect diverse patient populations. Here, we develop a ca
Externí odkaz:
https://doaj.org/article/20fb32eadefd4ac09f8fb1699d2139b7
Publikováno v:
In Journal of Steroid Biochemistry and Molecular Biology May 2021 209
Autor:
Kirby M. Donnelly, Cevannah M. Coleman, Madison L. Fuller, Victoria L. Reed, Dayna Smerina, David S. Tomlinson, Margaret M. Panning Pearce
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The hypothesis that pathogenic protein aggregates associated with neurodegenerative diseases spread from cell-to-cell in the brain in a manner akin to infectious prions has gained substantial momentum due to an explosion of research in the past 10–
Externí odkaz:
https://doaj.org/article/0641091592684ffc81562a7a343ee777
Autor:
Syed Imran Ali Shah, Hannah C. P. Wilson, Paul D. Abel, Richard J. Wassersug, Vít Třebický, Jitka Třebická Fialová, Caroline Allen, Hans H. Adomat, Robert H. Bell, Emma S. Tomlinson Guns, S. Craig Roberts
Publikováno v:
Journal of Men's Health, Vol 17, Iss 3, Pp 69-76 (2021)
Background and objective: Luteinizing hormone-releasing hormone agonists (LHRHa) suppress gonadal hormone production and are commonly used to treat prostate cancer (PC) in men and conditions ranging from uterine fibroids to estrogen-sensitive cancers
Externí odkaz:
https://doaj.org/article/98d3502b0b924755995720504d5d9087
Autor:
Na Sun, Benjamin V. Tran, Zishan Peng, Jing Wang, Ceng Zhang, Peng Yang, Tiffany X. Zhang, Josephine Widjaja, Ryan Y. Zhang, Wenxi Xia, Alexandra Keir, Jia‐Wei She, Hsiao‐hua Yu, Jing‐Jong Shyue, Hongguang Zhu, Vatche G. Agopian, Renjun Pei, James S. Tomlinson, Jeffrey A Toretsky, Steven J. Jonas, Noah Federman, Shaohua Lu, Hsian‐Rong Tseng, Yazhen Zhu
Publikováno v:
Advanced Science, Vol 9, Iss 14, Pp n/a-n/a (2022)
Abstract Well‐preserved molecular cargo in circulating extracellular vesicles (EVs) offers an ideal material for detecting oncogenic gene alterations in cancer patients, providing a noninvasive diagnostic solution for detection of disease status an
Externí odkaz:
https://doaj.org/article/e83cdc5dfac74fc9b17ad5ef7d4815e1
Autor:
Paul Winograd, Shuang Hou, Colin M. Court, Yi‐Te Lee, Pin‐Jung Chen, Yazhen Zhu, Saeed Sadeghi, Richard S. Finn, Pai‐Chi Teng, Jasmin J. Wang, Zhicheng Zhang, Hongtao Liu, Ronald W. Busuttil, James S Tomlinson, Hsian‐Rong Tseng, Vatche G. Agopian
Publikováno v:
Hepatology Communications, Vol 4, Iss 10, Pp 1527-1540 (2020)
Hepatocellular carcinoma (HCC) is a leading cause of mortality. Checkpoint inhibitors of programmed cell death protein‐1 (PD‐1) and programmed death‐ligand 1 (PD‐L1) have shown great efficacy, but lack biomarkers that predict response. Circul
Externí odkaz:
https://doaj.org/article/8f653ab4e8ff457f85cdc0e338e80ff2