Zobrazeno 1 - 10
of 190
pro vyhledávání: '"S, Symchowicz"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 22:1017-1021
The pharmacokinetics of netilmicin, gentamicin, and tobramycin in plasma and in perilymph of guinea pigs were studied after a single intravenous injection of 40 mg/kg. Detailed pharmacokinetic analysis of the plasma drug concentration-time data up to
Autor:
C Lin, S Symchowicz
Publikováno v:
Drug Metabolism Reviews. 4:75-95
(1975). Absorption, Distribution, Metabolism, and Excretion of Griseofulvin in Man and Animals. Drug Metabolism Reviews: Vol. 4, No. 1, pp. 75-95.
Publikováno v:
Journal of Endocrinology. 35:379-383
SUMMARY Anterior pituitaries from young female rats were incubated in Krebs-Ringer solution at 37° for 4·5–5 hr. A purified acetic acid extract of pig hypothalami was added, at various concentrations, to the incubation medium. The results show th
Autor:
S. Symchowicz, C. A. Korduba
Publikováno v:
Annals of the New York Academy of Sciences. 150:219-225
Publikováno v:
Xenobiotica. 2:507-515
1. After inhalation of doses of 3H-albuterol (84 and 220 μg) by humans, plasma radioactivity reached a max. after 2 and 4 h, respectively.2. About 72% of the inhaled dose was excreted within 24 h i...
Publikováno v:
British Journal of Pharmacology. 34:484-492
1 . Cocaine did not antagonize the tyramine-induced contractile response of the isolated rat vas deferens at the same concentrations which markedly potentiated the contractile response to noradrenaline. 2 . Imipramine and amitriptyline non-competitiv
Publikováno v:
Journal of Pharmaceutical Sciences. 56:912-914
Blood diazoxide levels were measured in six adult human males at various times after i.v. drug administration. On the basis of these results, the diazoxide half-life in blood was determined as 28.0 ± 8.3 hr. The presence of diazoxide in blood was ve
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 5(3)
The major urinary metabolite of albuterol in man was isolated and purified by ion-exchange chromatography and countercurrent distribution. On the basis of proton magnetic resonance, infrared, and mass-spectral analysis, enzymic hydrolysis, and assay
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 12(4)
The disposition of 14C-quazepam (7-chloro-(2,2,2-trifluoroethyl) [5-14C]-5-o-fluorophenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-thione), a new benzodiazepine hypnotic, was studied in hamsters and mice after iv and po dosing. In both species, quazepam wa
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 190(3)