Zobrazeno 1 - 10
of 1 375
pro vyhledávání: '"S, Stoll"'
Autor:
Qi Hao, Manoj K. Rathinaswamy, Kelly L. Klinge, Matthew Bratkowski, Amirhossein Mafi, Christina K. Baumgartner, Keith M. Hamel, Gesine K. Veits, Rinku Jain, Claudio Catalano, Mark Fitzgerald, Alexander W. Hird, Eunice Park, Harit U. Vora, James A. Henderson, Kenton Longenecker, Charles W. Hutchins, Wei Qiu, Giovanna Scapin, Qi Sun, Vincent S. Stoll, Chaohong Sun, Ping Li, Dan Eaton, David Stokoe, Stewart L. Fisher, Christopher G. Nasveschuk, Marcia Paddock, Michael E. Kort
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract PTPN2 (protein tyrosine phosphatase non-receptor type 2, or TC-PTP) and PTPN1 are attractive immuno-oncology targets, with the deletion of Ptpn1 and Ptpn2 improving response to immunotherapy in disease models. Targeted protein degradation ha
Externí odkaz:
https://doaj.org/article/1f2680b79836478cba894b08e1a585a6
Autor:
Janani Sridar, Amirhossein Mafi, Russell A. Judge, Jun Xu, Kailyn A. Kong, John C. K. Wang, Vincent S. Stoll, Georgios Koukos, Reyna J. Simon, Dan Eaton, Matthew Bratkowski, Qi Hao
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Pregnancy-Associated Plasma Protein A isoforms, PAPP-A and PAPP-A2, are metalloproteases that cleave insulin-like growth factor binding proteins (IGFBPs) to modulate insulin-like growth factor signaling. The structures of homodimeric PAPP-A
Externí odkaz:
https://doaj.org/article/ffd1e468f9a64aa5af47d5907712f034
Autor:
Eric R. Goedken, Maria A. Argiriadi, Justin D. Dietrich, Andrew M. Petros, Navasona Krishnan, Sanjay C. Panchal, Wei Qiu, Haihong Wu, Haizhong Zhu, Ashley M. Adams, Pierre M. Bodelle, Lucas Goguen, Paul L. Richardson, Peter F. Slivka, Myron Srikumaran, Anup K. Upadhyay, Bainan Wu, Russell A. Judge, Anil Vasudevan, Sujatha M. Gopalakrishnan, Philip B. Cox, Vincent S. Stoll, Chaohong Sun
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Anti-IL17A therapies have proven effective for numerous inflammatory diseases including psoriasis, axial spondylitis and psoriatic arthritis. Modulating and/or antagonizing protein–protein interactions of IL17A cytokine binding to its cell
Externí odkaz:
https://doaj.org/article/73a129f16e244becaaa09ce714e81a66
Publikováno v:
Magnetic Resonance, Vol 3, Pp 101-110 (2022)
Double electron–electron resonance (DEER) spectroscopy measures the distribution of distances between two electron spins in the nanometer range, often on doubly spin-labeled proteins, via the modulation of a refocused spin echo by the dipolar inter
Externí odkaz:
https://doaj.org/article/bd6ea69e6f0a44d2b535a7569871918c
Autor:
Qi Hao, Jin-Mi Heo, Boguslaw P. Nocek, Kevin G. Hicks, Vincent S. Stoll, Clint Remarcik, Sean Hackett, Lauren LeBon, Rinku Jain, Dan Eaton, Jared Rutter, Yao Liang Wong, Carmela Sidrauski
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The activity of translation initiation factor eIF2B is known to be modulated through stress-responsive phosphorylation of its substrate eIF2. Here, the authors uncover the regulation of eIF2B by the binding of sugar phosphates, suggesting a link betw
Externí odkaz:
https://doaj.org/article/7dab3274bc6948168fa0acd7979be94e
Publikováno v:
Magnetic Resonance, Vol 2, Pp 161-173 (2021)
Double electron–electron resonance (DEER) is a pulse electron paramagnetic resonance (EPR) technique that measures distances between paramagnetic centres. It utilizes a four-pulse sequence based on the refocused Hahn spin echo. The echo decays with
Externí odkaz:
https://doaj.org/article/78f4de0e976d4ebdaa1c4d296a81c0fe
Publikováno v:
Magnetic Resonance, Vol 1, Pp 209-224 (2020)
Dipolar electron paramagnetic resonance (EPR) spectroscopy (DEER and other techniques) enables the structural characterization of macromolecular and biological systems by measurement of distance distributions between unpaired electrons on a nanometer
Externí odkaz:
https://doaj.org/article/350d82821d9745d4be859e988e60471d
Autor:
Joshua S. Stoll, Hannah L. Harrison, Emily De Sousa, Debra Callaway, Melissa Collier, Kelly Harrell, Buck Jones, Jordyn Kastlunger, Emma Kramer, Steve Kurian, M. Alan Lovewell, Sonia Strobel, Tracy Sylvester, Brett Tolley, Andrea Tomlinson, Easton R. White, Talia Young, Philip A. Loring
Publikováno v:
Frontiers in Sustainable Food Systems, Vol 5 (2021)
Export-oriented seafood trade faltered during the early months of the COVID-19 pandemic. In contrast, alternative seafood networks (ASNs) that distribute seafood through local and direct marketing channels were identified as a “bright spot.” In t
Externí odkaz:
https://doaj.org/article/63e321f22416414ba35e24cecf9f62ef
Publikováno v:
Conservation Letters, Vol 13, Iss 1, Pp n/a-n/a (2020)
Abstract Seafood certifications are a prominent tool being used to encourage sustainability in marine fisheries worldwide. However, questions about their efficacy remain the subject of ongoing debate. A main criticism is that they are not well suited
Externí odkaz:
https://doaj.org/article/69dab5f8d07d4b22a80ed861ccdda123
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