Výsledky vyhledávání - "S, Stenstrom"

Muscarinic responses and binding in a murine neuroblastoma clone (N1E-115). Selective loss with subculturing of the low-affinity agonist site mediating cyclic GMP formation

Autor: M, McKinney, S, Stenstrom, E, Richelson

Publikováno v: Molecular pharmacology. 26(2)

Cells of the murine neuroblastoma clone N1E-115 possess muscarinic receptors that influence the intracellular level of cyclic nucleotides. The stimulation of [3H]cyclic GMP levels occurs only with intact cells and has an EC50 near the "low-affinity"

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b2d434660f34f567db4622dbf91fe3b5
https://pubmed.ncbi.nlm.nih.gov/6148690

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Muscarinic responses and binding in a murine neuroblastoma clone (N1E-115). Mediation of separate responses by high affinity and low affinity agonist-receptor conformations

Autor: M, McKinney, S, Stenstrom, E, Richelson

Publikováno v: Molecular pharmacology. 27(2)

Murine neuroblastoma cells (clone N1E-115) possess muscarinic receptors that mediate multiple responses, including the elevation of cyclic GMP levels and the inhibition of receptor-mediated increases in cyclic AMP. Evidence is presented showing that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f1621f705009c74f0b2fcaa80689bf26
https://pubmed.ncbi.nlm.nih.gov/2982089

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Acute effects of ethanol and other short-chain alcohols on the guanylate cyclase system of murine neuroblastoma cells (clone N1E-115)

Autor: S, Stenstrom, L, Enloe, M, Pfenning, E, Richelson

Publikováno v: The Journal of pharmacology and experimental therapeutics. 236(2)

The acute effects of ethanol were studied on the guanylate cyclase system of cultured murine neuroblastoma clone N1E-115. Using intact cells, we found that although ethanol had no effect on basal levels of cyclic GMP synthesis, it rapidly inhibited i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::59d889d01190230e9fbcc38922a8b025
https://pubmed.ncbi.nlm.nih.gov/2868120

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Effects of chronic exposure to ethanol on the prostaglandin E1 receptor-mediated response and binding in a murine neuroblastoma clone (N1E-115)

Autor: E, Richelson, S, Stenstrom, C, Forray, L, Enloe, M, Pfenning

Publikováno v: The Journal of pharmacology and experimental therapeutics. 239(3)

With the use of cultured murine neuroblastoma cells (clone N1E-115), the authors studied the effects of chronic ethanol on prostaglandin E, (PGE1)-mediated cyclic AMP formation, adenylate cyclase activity and [3H]PGE1 binding. Whereas acute exposure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::49a2c7964038cf67acaca0d24bd8b509
https://pubmed.ncbi.nlm.nih.gov/2879032

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Pseudo-noncompetitive antagonism of muscarinic receptor-mediated cyclic GMP formation and phosphoinositide hydrolysis by pirenzepine

Autor: E E, el-Fakahany, W, Surichamorn, C L, Amrhein, S, Stenstrom, C L, Cioffi, E, Richelson, M, McKinney

Publikováno v: The Journal of pharmacology and experimental therapeutics. 247(3)

Pirenzepine selectively antagonized muscarinic receptor-mediated cyclic GMP formation in a noncompetitive fashion in mouse neuroblastoma cells (clone N1E-115). These effects of pirenzepine were time- and concentration-dependent and they were also rev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::825284b342c4a68ae4e36bd5733573e8
https://pubmed.ncbi.nlm.nih.gov/2849677

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