Insights into the COVID-19 pandemic: Origin, pathogenesis, diagnosis, and therapeutic interventions

Autor: Mahmoud M. Berekaa

Publikováno v: Frontiers in Bioscience-Elite, Vol 13, Iss 1, Pp 117-139 (2020)

Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a member of the human coronavirus (HCoV) family that targets the lower part of the respiratory tract and causes severe acute respiratory syndrom

Externí odkaz: https://doaj.org/article/fca2cbcd7de646088a2ca4682ab44b55

Safety, Virologic Efficacy, and Pharmacokinetics of CT-P59, a Neutralizing Monoclonal Antibody Against SARS-CoV-2 Spike Receptor-Binding Protein: Two Randomized, Placebo-Controlled, Phase I Studies in Healthy Individuals and Patients With Mild SARS-CoV-2 Infection

Autor: Jin Gyu Jung, Sunghyun Kim, Bum Soo Kim, Anca Streinu-Cercel, Oana Săndulescu, Da Bee Jeon, Adrian Streinu-Cercel, Seul Gi Lee, Sang Joon Lee, Yeon Sook Kim, Yeo Jin Lee, Jin Yong Kim, Yeon Mi Lee, Min Kyung Kim, Jae-Hyeong Park, Jang Hee Hong, Jeong Eun Park, Young Rock Jang, Na Hyun Jung

Publikováno v: Clinical Therapeutics

PURPOSE: Neutralizing antibodies can reduce SARS-CoV-2 cellular entry, viral titers, and pathologic damage. CT-P59 (regdanvimab), a SARS-CoV-2 neutralizing monoclonal antibody, was examined in 2 randomized, double-blind, placebo-controlled, single as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be168aec276ef873b11c98eb98586b40
https://doi.org/10.1016/j.clinthera.2021.08.009

Longitudinal assessment of anti-SARS-CoV-2 antibody dynamics and clinical features following convalescence from a COVID-19 infection

Autor: Volker Ast, Maximilian Kittel, Margot Thiaucourt, Verena Haselmann, Catharina Gerhards, Michael Neumaier, Michael Hetjens, Celine Becker

Publikováno v: International Journal of Infectious Diseases, Vol 107, Iss, Pp 221-227 (2021)
International Journal of Infectious Diseases

INTRODUCTION: The longevity of antibody levels against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the duration of immunity are current topics of major scientific interest. Antibody kinetics during the acute phase are well studie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e129526dae97bea65e1b07a30d84fd
http://www.sciencedirect.com/science/article/pii/S1201971221003921

Natural medicinal plant products as an immune-boosters: A possible role to lessen the impact of Covid-19

Autor: Sanjit Sinha, Sujoy Midya, Sk Md Abu Imam Saadi, Sk Saruk Islam

Publikováno v: Case Studies in Chemical and Environmental Engineering, Vol 4, Iss, Pp 100105-(2021)
Case Studies in Chemical and Environmental Engineering

Transmissible Covid-19, caused by novel corona virus since last of 2019 has outspread widely until now. Where, India was the second most affected country and 3rd in mortality rate. In world ancient history, medicinal plants were played a crucial role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e05a4de3afed33cc2c0ca2aaa7095ae
http://www.sciencedirect.com/science/article/pii/S266601642100027X

Longitudinal evaluation of the Abbott ARCHITECT SARS-CoV-2 IgM and IgG assays in a pediatric population

Autor: Mark D. Gonzalez, Cristina Interiano, Mohamed Elkhalifa, Sheicho Muze, Elizabeth P Weinzierl, Brian Turner, Van Leung-Pineda, Robert C. Jerris, Beverly Barton Rogers

Publikováno v: Practical Laboratory Medicine, Vol 25, Iss, Pp e00208-(2021)
Practical Laboratory Medicine

Background Clinical laboratory testing has been an essential part of COVID-19 management. Serology can provide valuable information regarding a patient’s exposure to virus, and may have a larger role to play as vaccines becomes available. Limited d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b5b0c4162f1f770746d8612e810c8e
http://www.sciencedirect.com/science/article/pii/S2352551721000081