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The Phosphatase PRL-3 Is Involved in Key Steps of Cancer Metastasis

Autor: Laura Duciel, S Saule, Maria Kondratova, Luis Cristobal Monraz Gomez, Inna Kuperstein

Publikováno v: Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2019, 431, pp.3056-3067. ⟨10.1016/j.jmb.2019.06.008⟩

PRL-3 belongs to the PRL phosphatase family. Its physiological role remains unclear, but many studies have identified that PRL-3 is a marker of cancer progression and shown it to be associated with metastasis. Evidence implicating PRL-3 in various el

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cefe3865ada4c8fd549253f2ef596f5
https://doi.org/10.1016/j.jmb.2019.06.008

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Involvement of Bcl-2-Associated Transcription Factor 1 in the Differentiation of Early-Born Retinal Cells

Autor: J. P. McPherson, Xavier Guillonneau, Jerome E. Roger, José-Alain Sahel, L. Picault, Olivier Goureau, S. Saule, Gaël Orieux, Amélie Slembrouck

Publikováno v: The Journal of Neuroscience. 34:1530-1541

Retinal progenitor proliferation and differentiation are tightly controlled by extrinsic cues and distinctive combinations of transcription factors leading to the generation of retinal cell type diversity. In this context, we have characterized Bcl-2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9737de277842b87f3dcdca86d3142f5f
https://doi.org/10.1523/jneurosci.3227-13.2014

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Protein Tyrosine Phosphatase 4A3 (PTP4A3) Promotes Human Uveal Melanoma Aggressiveness Through Membrane Accumulation of Matrix Metalloproteinase 14 (MMP14)

Autor: Nathalie Cassoux, Océane Anezo, Nathalie Planque, Cécile Laurent, S Saule, Sophie Piperno-Neumann, Selma Maacha, Malika Foy, Laurence Mery, Xavier Sastre-Garau, Géraldine Liot

Publikováno v: Investigative ophthalmologyvisual science. 57(4)

PURPOSE To study PTP4A3 phosphatase and MMP14 metalloprotease synergy in uveal melanoma aggressiveness. METHODS Cell membrane localization of matrix metalloprotease 14 (MMP14) in uveal melanoma cells expressing protein tyrosine phosphatase A3 (PTP4A3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8feed9754f6d0ba89c09ee83fbec24
https://pubmed.ncbi.nlm.nih.gov/27096756

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Down regulation of pRb in cultures of avian neuroretina cells promotes proliferation of reactive Müller-like cells and emergence of retinal stem/progenitors

Autor: Danielle Laugier, Georges Calothy, Céline Lebuhotel, Audrey Chapelle, Maria Marx, S Saule

Publikováno v: Experimental Eye Research. 90:791-801

The aim of this work was to define the role of pRb depletion in the proliferation and differentiation of avian retinoblasts in vitro. For this purpose vectors expressing pRb short hairpin RNA were used to deplete pRb in cultures of avian neuroretinal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee25f9724b191d19f7706554be8ea37
https://doi.org/10.1016/j.exer.2010.03.015

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Genomic profiling and identification of high-risk tumours in uveal melanoma by array-CGH analysis of primary tumours and liver metastases

Autor: S. Saule, Xavier Sastre, J. Trolet, Sophie Piperno-Neumann, Pascale Mariani, Laurence Desjardins, Bernard Asselain, P. Hupe, Jérôme Couturier, Emmanuel Barillot

Publikováno v: Acta Ophthalmologica. 86

Purpose Current therapeutic efforts in Uveal Melanoma are directed toward detection of liver metastases at an earlier stage and adjuvant systemic therapy in high risk patients. Beside clinical and histological features, specific cytogenetic alteratio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fee6cf92d813031d6f51a8f13c5c43b0
https://doi.org/10.1111/j.1755-3768.2008.5364.x

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myc products induce the expression of catecholaminergic traits in quail neural crest-derived cells

Autor: S Saule, Mireille Fauquet, D. Stehelin

Publikováno v: Proceedings of the National Academy of Sciences. 87:1546-1550

The avian myelocytomatosis virus strain MC29 v-myc oncogene transforms a wide panel of avian cells in vitro and either blocks or maintains differentiation, depending on the cell type. In the present work, we have investigated the effect of this oncog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ad6d6238af4833c192ca588c16ac49
https://doi.org/10.1073/pnas.87.4.1546

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[Normal and malignant choroidal melanocytes: from cell to clinical approach]

Autor: F, Mouriaux, S, Saule, L, Desjardins, F, Mascarelli

Publikováno v: Journal francais d'ophtalmologie. 28(7)

The molecular and cellular basis of human choroidal malignant melanoma progression has remained largely unknown. However, choroidal melanoma is the most important primary intraocular tumor in adults. Developmentally, choroidal melanocytes are of neur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::76e6e5eb7daf97377394f65b2d40e044
https://pubmed.ncbi.nlm.nih.gov/16208231

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