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Publikováno v:
Cell Transplantation, Vol 15 (2006)
Cell therapy is a potentially powerful tool in the treatment of many grave disorders including leukemia, immune deficiencies, autoimmune diseases, and diabetes. However, finding matched donors is challenging and recipients may suffer from the severe
Externí odkaz:
https://doaj.org/article/a049fc48e50a4c008f82c1a798ee658f
Autor:
R. Shamekh, J. Newcomb, J. Mallery, C. J. Cassady, S. Saporta, D. F. Cameron, P. R. Sanberg, A. E. Willing
Publikováno v:
Cell Transplantation, Vol 14 (2005)
Transplanting cells across species (xenotransplantation) for the treatment of Parkinson's disease has been considered an option to alleviate ethical concerns and shortage of tissues. However, using this approach leads to decreased cell survival; the
Externí odkaz:
https://doaj.org/article/a991732795af4dda8a69ab77e6492cea
Autor:
D. F. Cameron Ph.D., J. J. Hushen, T. Dejarlais, L. Colado, K. M. Wolski, P. R. Sanberg, S. Saporta
Publikováno v:
Cell Transplantation, Vol 11 (2002)
In the absence of a definitive cell marker for testis-derived Sertoli cells, their identification in cell culture or in Sertoli cell-facilitated cell transplantation protocols is difficult and limits the creditable evaluation of experimental results.
Externí odkaz:
https://doaj.org/article/214d3d00171040a59b0d11ba609ec74e
Autor:
J. Sanchez-Ramos, S. Song, M. Dailey, F. Cardozo-Pelaez, C. Hazzi, T. Stedeford, A. Willing, T. B. Freeman, S. Saporta, T. Zigova, P. R. Sanberg, E. Y. Snyder
Publikováno v:
Cell Transplantation, Vol 9 (2000)
Cell transplantation into host brain requires a reliable cell marker to trace lineage and location of grafted cells in host tissue. The lacZ gene encodes the bacterial (E. coli) enzyme β-galactosidase (β-gal) and is commonly visualized as a blue in
Externí odkaz:
https://doaj.org/article/930fcd7873fa44f489ebf4dbe342581f
Autor:
D.F. Cameron Ph.D., A.I. Othberg, C.V. Borlongan, S. Rashed, A. Anton, S. Saporta, P.R. Sanberg
Publikováno v:
Cell Transplantation, Vol 6 (1997)
Testis-derived Sertoli cells have been used to create an immune “privileged” site outside of the testis to facilitate cell transplantation protocols for diabetes and neurodegenerative diseases. In addition to secreting immunoprotective factors, S
Externí odkaz:
https://doaj.org/article/9d91c543d52a4fdaa2db3528307efad3
Autor:
S. Saporta, C.N.R. Henderson
Publikováno v:
Journal of Neuroscience Methods. 37:233-240
The effects of dissolving horseradish peroxidase (HRP) or HRP conjugated to wheatgerm agglutinin (WGA-HRP) in radiocontrast media (MD76) on the intraaxonal transport and enzymatic activity of these tracers were evaluated both in vivo and in vitro. Th
Publikováno v:
Experimental brain research. 165(4)
NF-kappaB is a ubiquitous nuclear transcription factor that regulates a number of physiological processes. NF-kappaB activity has been implicated in enhancing neuronal survival following CNS injury. The present study was conducted to test the hypothe
Publikováno v:
Anticancer research. 20(6B)
We have previously reported that invasiveness of mouse glioma G-26, which expresses CD44 adhesion molecule, was inhibited in vitro following treatment with anti-CD44 antibody or mouse interferon alpha/beta (MuIFN alpha/beta). Here, we evaluated wheth
Publikováno v:
Progress in brain research. 127