Zobrazeno 1 - 10
of 145
pro vyhledávání: '"S, Rutten"'
Autor:
Martijn G. S. Rutten, Yu Lei, Joanne H. Hoogerland, Vincent W. Bloks, Hong Yang, Trijnie Bos, Kishore A. Krishnamurthy, Aycha Bleeker, Mirjam H. Koster, Rachel E. Thomas, Justina C. Wolters, Hilda van den Bos, Gilles Mithieux, Fabienne Rajas, Adil Mardinoglu, Diana C. J. Spierings, Alain de Bruin, Bart van de Sluis, Maaike H. Oosterveer
Publikováno v:
Cancer & Metabolism, Vol 11, Iss 1, Pp 1-11 (2023)
Abstract Background Glycogen storage disease type 1a (GSD Ia) is an inborn error of metabolism caused by a defect in glucose-6-phosphatase (G6PC1) activity, which induces severe hepatomegaly and increases the risk for liver cancer. Hepatic GSD Ia is
Externí odkaz:
https://doaj.org/article/176971327ab64839a0921d89e984a866
Autor:
Alessandro Rossi, Martijn G. S. Rutten, Theo H. van Dijk, Barbara M. Bakker, Dirk-Jan Reijngoud, Maaike H. Oosterveer, Terry G. J. Derks
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Hypoglycemia results from an imbalance between glucose entering the blood compartment and glucose demand, caused by a defect in the mechanisms regulating postprandial glucose homeostasis. Hypoglycemia represents one of the most common metabolic emerg
Externí odkaz:
https://doaj.org/article/aa2748dec44245458a088fa145090a7d
Autor:
Jeanine J. S. Rutten, Laura W. van Buul, Martin Smalbrugge, Suzanne E. Geerlings, Debby L. Gerritsen, Stephanie Natsch, Philip D. Sloane, Ruth B. Veenhuizen, Johannes C. van der Wouden, Cees M. P. M. Hertogh
Publikováno v:
BMC Geriatrics, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background Antibiotic overprescribing for suspected urinary tract infection (UTI) in nursing homes (NHs) is common. Typical clinical scenarios in which antibiotics are inappropriately prescribed include response to nonspecific signs and symp
Externí odkaz:
https://doaj.org/article/4900018ab28f4786a25acc7497626f14
Autor:
Federica Sarno, Désirée Goubert, Emilie Logie, Martijn G. S. Rutten, Mihaly Koncz, Christophe Deben, Anita E. Niemarkt, Lucia Altucci, Pernette J. Verschure, Antal Kiss, Wim Vanden Berghe, Marianne G. Rots
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 102 (2022)
Plasminogen activator, urokinase (PLAU) is involved in cell migration, proliferation and tissue remodeling. PLAU upregulation is associated with an increase in aggressiveness, metastasis, and invasion of several cancer types, including breast cancer.
Externí odkaz:
https://doaj.org/article/96a430b70388450ba692e106845876d2
Autor:
L. P. W. Canjels, C. Ghossein‐Doha, R. J. Alers, S. Rutten, M. van den Kerkhof, V. M. M. M. Schiffer, E. Mulder, S. C. Gerretsen, A. P. Aldenkamp, P. P. M. Hurks, V. van de Ven, M. E. A. Spaanderman, J. F. A. Jansen, W. H. Backes
Publikováno v:
Ultrasound in Obstetrics & Gynecology, 60(4), 532-540. Wiley
Pre-eclampsia is a vascular complication of pregnancy, associated with a long-term risk of cerebrovascular and mental disorders. We explored whether formerly pre-eclamptic women exhibit differences in functional brain organization, especially in regi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa8f118ef57d81b7ad3341832385d0d
https://cris.maastrichtuniversity.nl/en/publications/5d6db991-1f20-4492-a741-1d4827ce1a90
https://cris.maastrichtuniversity.nl/en/publications/5d6db991-1f20-4492-a741-1d4827ce1a90
Akademický článek
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Publikováno v:
Journal of Inherited Metabolic Disease
Gene therapy is currently considered as the optimal treatment for inborn errors of metabolism (IEMs), as it aims to permanently compensate for the primary genetic defect. However, emerging gene editing approaches such as CRISPR‐Cas9, in which the D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4449488d4f4891aba8864d2ff1940d
https://doi.org/10.1002/jimd.12093
https://doi.org/10.1002/jimd.12093
Autor:
Bertien Dethmers-Ausema, Niels J. Kloosterhuis, Folkert Kuipers, Gilles Mithieux, Anouk M. La Rose, Martijn G S Rutten, Oliver Soehnlein, Joanne A Hoogerland, J Hendrik Nijland, Marit Westerterp, Fabienne Rajas, Maaike H. Oosterveer, Arthur Flohr Svendsen, Venetia Bazioti, Michaël V. Lukens, Martijn van Faassen, Anouk G. Groenen
Publikováno v:
Molecular metabolism
Molecular metabolism, Elsevier, 2021, pp.101265. ⟨10.1016/j.molmet.2021.101265⟩
Molecular metabolism, 53:101265, 1-14. ELSEVIER SCIENCE BV
Molecular Metabolism, Vol 53, Iss, Pp 101265-(2021)
Molecular Metabolism
Molecular metabolism, Elsevier, 2021, pp.101265. ⟨10.1016/j.molmet.2021.101265⟩
Molecular metabolism, 53:101265, 1-14. ELSEVIER SCIENCE BV
Molecular Metabolism, Vol 53, Iss, Pp 101265-(2021)
Molecular Metabolism
Objective Glycogen storage disease type 1a (GSD Ia) is a rare inherited metabolic disorder caused by mutations in the glucose-6-phosphatase (G6PC1) gene. When untreated, GSD Ia leads to severe fasting-induced hypoglycemia. Although current intensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0fee94b82da6e1129feb4ffc5aac411
https://www.hal.inserm.fr/inserm-03257584/document
https://www.hal.inserm.fr/inserm-03257584/document
Autor:
Jeanine J S Rutten, Laura W van Buul, Martin Smalbrugge, Karlijn J. Joling, Cees M.P.M. Hertogh, Anouk M. van Loon, Janine van Kooten
Publikováno v:
Journal of the American Medical Directors Association, 21(12), 1791-1797.e1. Elsevier Inc.
Journal of the American Medical Directors Association
Rutten, J J S, van Loon, A M, van Kooten, J, van Buul, L W, Joling, K J, Smalbrugge, M & Hertogh, C M P M 2020, ' Clinical Suspicion of COVID-19 in Nursing Home Residents : Symptoms and Mortality Risk Factors ', Journal of the American Medical Directors Association, vol. 21, no. 12, pp. 1791-1797.e1 . https://doi.org/10.1016/j.jamda.2020.10.034
Journal of the American Medical Directors Association
Rutten, J J S, van Loon, A M, van Kooten, J, van Buul, L W, Joling, K J, Smalbrugge, M & Hertogh, C M P M 2020, ' Clinical Suspicion of COVID-19 in Nursing Home Residents : Symptoms and Mortality Risk Factors ', Journal of the American Medical Directors Association, vol. 21, no. 12, pp. 1791-1797.e1 . https://doi.org/10.1016/j.jamda.2020.10.034
Objectives To describe symptomatology, mortality and risk factors for mortality in a large group of Dutch nursing home (NH) residents with clinically-suspected COVID-19 who were tested with a Reverse Transcription Polymerase Chain Reaction (RT-PCR) t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa8af067335185e08a6e1414ae828d8
https://research.vumc.nl/en/publications/0bb6eb44-3e8f-403c-853f-4e2ec5d5ee7c
https://research.vumc.nl/en/publications/0bb6eb44-3e8f-403c-853f-4e2ec5d5ee7c
Autor:
Martijn G S Rutten, Mathilde J.C. Broekhuis, Tobias Ackermann, Gertrud Kortman, Mohamad A. Zaini, Cornelis F. Calkhoven, Götz Hartleben, Hidde R. Zuidhof
Oncogene-induced metabolic reprograming supports cell growth and proliferation. Yet, it also links cancer cell survival to certain metabolic pathways and nutrients. In order to synthesise amino acids and nucleotidesde novofor growth and proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4ac7c0b7e1785911f954090c697d490
https://doi.org/10.1101/2020.10.09.333104
https://doi.org/10.1101/2020.10.09.333104