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Nod2 influences microbial resilience and susceptibility to colitis following antibiotic exposure

Autor: A, Goethel, W, Turpin, S, Rouquier, G, Zanello, S J, Robertson, C J, Streutker, D J, Philpott, K, Croitoru

Publikováno v: Mucosal immunology. 12(3)

Inflammatory bowel disease (IBD) etiology involves genetic susceptibility, environmental triggers, and the gut microbiome. Antibiotic exposure is associated with IBD, both in early life and adulthood. Here, we investigated whether Nod2-deficiency inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0374927a91678250d022e35e3dc073f2
https://pubmed.ncbi.nlm.nih.gov/30858507

The loss of olfactory receptor genes in human evolution

Autor: D. Giorgi, S. Rouquier

Publikováno v: Evolution of Nervous Systems vol. 5. The Evolution of Primate Nervous Systems
Jon H Kaas. Evolution of Nervous Systems vol. 5. The Evolution of Primate Nervous Systems, Academic Press : Oxford 2007, pp.129-140, 2007
HAL

The sense of smell is mediated by olfactory receptors that bind odorants. Olfactory receptors are encoded by a large multigene family. During the evolution of primates, a large fraction of this repertoire became nonfunctional in great apes and humans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77cd4b2dfbb75e4e901ac77f509c2dff
https://hal.archives-ouvertes.fr/hal-00193379

OR11H1 Missense Variant Confers the Susceptibility to Vogt‒Koyanagi‒Harada Disease by Mediating Gadd45g Expression.

Autor: Li, Xingran¹ (AUTHOR), Wang, Guoqing¹ (AUTHOR), Wang, Xiaotang¹ (AUTHOR), Li, Wanqian¹ (AUTHOR), Li, Na² (AUTHOR), Liu, Xianyang¹ (AUTHOR), Fan, Wei¹ (AUTHOR), He, Siyuan¹ (AUTHOR), Han, Yue³ (AUTHOR), Su, Guannan¹ (AUTHOR), Cao, Qingfeng¹ (AUTHOR), Yang, Peizeng¹ (AUTHOR) ypz@hospital.cqmu.edu.cn, Hou, Shengping^1,4 (AUTHOR) sphou828@mail.ccmu.edu.cn

Publikováno v: Advanced Science. 3/20/2024, Vol. 11 Issue 11, p1-9. 9p.

Sequence and expression of a candidate for the human Secretor blood group alpha(1,2)fucosyltransferase gene (FUT2). Homozygosity for an enzyme-inactivating nonsense mutation commonly correlates with the non-secretor phenotype

Autor: R J, Kelly, S, Rouquier, D, Giorgi, G G, Lennon, J B, Lowe

Publikováno v: The Journal of biological chemistry. 270(9)

Synthesis of soluble A, B, H, and Lewis b blood group antigens in humans is determined by the Secretor (Se) (FUT2) blood group locus. Genetic, biochemical, and molecular analyses indicate that this locus corresponds to an alpha(1,2)fucosyltransferase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d0a59b23e47e521652f626d0124fd157
https://pubmed.ncbi.nlm.nih.gov/7876235