Zobrazeno 1 - 10
of 132
pro vyhledávání: '"S, Raspanti"'
Publikováno v:
Journal of Physics: Conference Series. 2385:012081
The target of motorsport has always been maximising the performance. Increasingly stringent rules on fuel usage, however, have moved the research on engine design and control rules toward efficiency enhancement. Turbocharging is a typical solution to
Publikováno v:
Physica Medica. 92:S128-S129
Autor:
Roberto Sciagrà, Gian Franco Gensini, Richard Schulz, Giampaolo Cerisano, Anna Maria Gori, Paolo Colonna, Alice Sereni, Renato Valenti, Piergiovanni Buonamici, Rosanna Abbate, David Antoniucci, S. Raspanti, Betti Giusti
Publikováno v:
International Journal of Cardiology. 197:147-153
The TIPTOP (Early Short-term Doxycycline Therapy In Patients with Acute Myocardial Infarction and Left Ventricular Dysfunction to Prevent The Ominous Progression to Adverse Remodelling) trial demonstrated that a timely, short-term therapy with doxycy
Publikováno v:
European Journal of Organic Chemistry. 2014:7595-7604
Triazole-containing Arg-Gly-Asp (RGD) peptidomimetics capable of interacting with αvβ3 integrin were developed through click chemistry. The role of the diverse range of guanidine bioisosteres for the arginine mimetic moiety was evaluated in vitro t
Autor:
S. Raspanti, Pierangelo Fabbrizzi, Gloria Menchi, Francesca Bianchini, Andrea Trabocchi, Antonio Guarna
Publikováno v:
Tetrahedron. 70:5439-5449
Fragment-based drug discovery is a valuable tool in hit identification, as well as the combination of different small fragments showing a minimal binding activity against biological receptors or enzymes to give merged hits. A high number of fragments
Autor:
Piergiovanni Buonamici, S. Raspanti, Giampaolo Cerisano, David Antoniucci, Roberto Sciagrà, Renato Valenti, Roberta Romito, Alberto Pupi, Paolo Colonna, Nazario Carrabba, Emilio Vincenzo Dovellini, Alberto Santini
Publikováno v:
European Heart Journal. 35:184-191
Experimental studies suggest that doxycycline attenuates post-infarction remodelling and exerts protective effects on myocardial ischaemia/reperfusion injury. However, the effects of the drug in the clinical setting are unknown. The aim of this study
Autor:
E. Vanzi, Nicoletta Cini, Lido Calorini, Francesca Bianchini, Antonio Guarna, Gloria Menchi, Alberto Pupi, Andrea Trabocchi, S. Raspanti, Anna Bottoncetti
Publikováno v:
Journal of Medicinal Chemistry. 55:5024-5033
In this paper, using a hybrid small-animal Micro SPECT/CT imaging system, we report that a new (125)I-Cilengitide-like RGD-cyclopentapeptide, containing d-morpholine-3-carboxylic acid, interacts in vivo with α(v)β(3) integrin expressed by melanoma
Autor:
Gloria Menchi, Anna Bottoncetti, Elisa Danieli, Alberto Pupi, Antonio Guarna, S. Raspanti, Donatella Potenza, and Andrea Trabocchi, Nicoletta Cini
Publikováno v:
Amino Acids. 38:329-337
3-Aza-6,8-dioxabicyclo[3.2.1]octane-based amino acids as reverse turn inducers have been introduced into cyclic peptidomimetics containing the RGD or DGR retro-sequence, in order to achieve a stereochemical scanning of the binding capability of the r
Autor:
Anna Bottoncetti, Antonio Guarna, Alberto Pupi, Andrea Trabocchi, Gloria Menchi, Nicoletta Cini, S. Raspanti
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:1542-1549
Two c[RGDfX] cyclopeptides, having either L- or D-morpholine-3-COOH (Mor) as the X amino acid were developed as ligands for alpha(v)beta(3)/alpha(v)beta(5) integrins. Biological assays showed only d-Mor-containing cyclopentapeptide capable to bind al
Autor:
Emilio Vincenzo Dovellini, Mariasilvia Tommasi, Renato Valenti, Pucci P, David Antoniucci, Roberto Sciagrà, Alberto Pupi, Giampaolo Cerisano, S. Raspanti
Publikováno v:
Journal of Nuclear Cardiology. 15:644-654
Background. The relationship among plasma brain natriuretic peptide (BNP), markers of extracellular matrix (ECM) remodeling, and left ventricular (LV) dilation after reperfused acute myocardial infarction is poorly known. Methods and Results. Echocar