Zobrazeno 1 - 10
of 10 858
pro vyhledávání: '"S, Ramalingam"'
Autor:
Zhen Chen, Karin A. Vallega, Vijay K. Boda, Zihan Quan, Dongsheng Wang, Songqing Fan, Qiming Wang, Suresh S. Ramalingam, Wei Li, Shi‐Yong Sun
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract There is an urgent need to fully understand the biology of third generation EGFR‐tyrosine kinase inhibitors (EGFR‐TKIs), particularly osimertinib, and to develop mechanism‐driven strategies to manage their acquired resistance. Transien
Externí odkaz:
https://doaj.org/article/724fd6fccbf0485f8840bc5a1b713315
Autor:
Benjamin J. Solomon, M.B.B.S., PhD, Ibiayi Dagogo-Jack, MD, Se-Hoon Lee, MD, Michael J. Boyer, M.B.B.S., PhD, Suresh S. Ramalingam, MD, Enric Carcereny, MD, Enriqueta Felip, MD, PhD, Ji-Youn Han, MD, PhD, Toyoaki Hida, PhD, Brett G.M. Hughes, M.B.B.S., Sang-We Kim, MD, PhD, Makoto Nishio, MD, PhD, Takashi Seto, MD, Tatsuro Okamoto, MD, PhD, Xiaoxi Zhang, PhD, Jean-Francois Martini, PhD, Erjian Wang, MD, PhD, Steven De Beukelaer, MD, Todd M. Bauer, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 7, Pp 100685- (2024)
Introduction: The JAVELIN Lung 101 phase 1b/2 trial evaluated avelumab (immune checkpoint inhibitor) combined with lorlatinib or crizotinib (tyrosine kinase inhibitors) in ALK-positive or ALK-negative advanced NSCLC, respectively. Methods: Starting d
Externí odkaz:
https://doaj.org/article/50d39c846b474baea88547c6b345e6aa
Autor:
Peng Li, Haydn Kissick, Rebecca C Obeng, Tahseen H Nasti, Christiane S Eberhardt, Rafi Ahmed, Zhengjia Chen, Warren J Leonard, Suresh S Ramalingam, Andreas Wieland, Annapaola Mariniello, Jeffrey M Switchenko, Kylee Martens, Daniel Y Chang, Donald McGuire, Candace Daugherty, Yuzi Zhang, Rathi Pillai, Alice O Kamphorst
Publikováno v:
BMJ Oncology, Vol 3, Iss 1 (2024)
Objective Immune checkpoint inhibitors (ICI) that block the programmed cell death 1 (PD-1) pathway have shown promise with limited benefit. We and others have shown in small patient cohorts that an early proliferative CD8 T-cell response in the blood
Externí odkaz:
https://doaj.org/article/4cc0e384a52945fa895729f71406f6ed
Autor:
Madhusmita Behera, PhD, Renjian Jiang, MS, Zhonglu Huang, MS, Becky Bunn, MS, Murry W. Wynes, PhD, Jeffrey Switchenko, PhD, Giorgio V. Scagliotti, MD, Chandra P. Belani, MD, Suresh S. Ramalingam, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 6, Pp 100592- (2024)
Introduction: EGFR exon 20 insertion (ex20ins) mutations account for approximately 10% of EGFR mutations in lung adenocarcinoma. Patients with ex20ins mutation do not respond to standard EGFR tyrosine kinase inhibitor therapy. In this work, we analyz
Externí odkaz:
https://doaj.org/article/f92ad290cb7e478fb92426609abe2a43
Publikováno v:
Ain Shams Engineering Journal, Vol 15, Iss 5, Pp 102688- (2024)
An intelligent detection of the communication channel by the transceiver is what is known as cognitive radio (CR), a sort of radio communication. Avoid using channels that are already in use to reduce interference and swiftly direct traffic to open c
Externí odkaz:
https://doaj.org/article/a20ccd54daf64f19868899e21bf7c76e
Publikováno v:
Ain Shams Engineering Journal, Vol 15, Iss 3, Pp 102458- (2024)
Neighboring radio networks are those that do not instantly supply communications infrastructure after deployment, have radio transceivers with restricted transmission range, and are unaware of possible neighbors. Vehicle-to-vehicle communication is a
Externí odkaz:
https://doaj.org/article/4db4a03d0a0048dd8735ea03830ded80
Publikováno v:
Journal of Information Technology Management, Vol 15, Iss Special Issue: Digital Twin Enabled Neural Networks Architecture Management for Sustainable Computing, Pp 5-20 (2023)
Wireless Sensor Networks (WSNs) have been employed in various real-time applications and addressed fundamental issues, such as limited power resources and network life. Several sensor nodes in a WSN monitor the actual world and relay discovered data
Externí odkaz:
https://doaj.org/article/ffbb0038388044679e0ead3cc19ee9a3
Autor:
Sarah A. Westergaard, Manali Rupji, Lauren E. Franklin, Madhusmita Behera, Suresh S. Ramalingam, Kristin A. Higgins
Publikováno v:
Cancer Medicine, Vol 12, Iss 6, Pp 7339-7347 (2023)
Abstract Introduction Tobacco cessation is a critical but challenging intervention for cancer patients. Our National Cancer Institute‐designated Comprehensive Cancer Center instituted a tobacco cessation program in 2019. This manuscript reports on
Externí odkaz:
https://doaj.org/article/a2b1f08bf59b49508a2109caf908f457
Autor:
Juliann Chmielecki, Jhanelle E. Gray, Ying Cheng, Yuichiro Ohe, Fumio Imamura, Byoung Chul Cho, Meng-Chih Lin, Margarita Majem, Riyaz Shah, Yuri Rukazenkov, Alexander Todd, Aleksandra Markovets, J. Carl Barrett, Ryan J. Hartmaier, Suresh S. Ramalingam
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Osimertinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), potently and selectively inhibits EGFR-TKI-sensitizing and EGFR T790M resistance mutations. In the Phase III FLAURA study (NCT02296125), first-line osimer
Externí odkaz:
https://doaj.org/article/44b83896764b4d85bc01ecb3c4630dd4
Autor:
Juliann Chmielecki, Tony Mok, Yi-Long Wu, Ji-Youn Han, Myung-Ju Ahn, Suresh S. Ramalingam, Thomas John, Isamu Okamoto, James Chih-Hsin Yang, Frances A. Shepherd, Krishna C. Bulusu, Gianluca Laus, Barbara Collins, J. Carl Barrett, Ryan J. Hartmaier, Vassiliki Papadimitrakopoulou
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
In the phase III AURA3 study (NCT02151981), the third-generation epidermal growth factor receptor tyrosine kinase inhibitor osimertinib prolonged progression-free survival versus platinum-doublet chemotherapy in patients with EGFR T790M advanced NSCL
Externí odkaz:
https://doaj.org/article/97023c9e42e0450eab3688b9d4689761