Zobrazeno 1 - 10
of 52
pro vyhledávání: '"S, Pind"'
Autor:
William E. Balch, J M McCaffery, M G Farquhar, Howard W. Davidson, S. Pind, Helen Plutner, C Nuoffer
Publikováno v:
The Journal of Cell Biology
Members of the rab/YPT1/SEC4 gene family of small molecular weight GTPases play key roles in the regulation of vesicular traffic between compartments of the exocytic pathway. Using immunoelectron microscopy, we demonstrate that a dominant negative ra
Publikováno v:
The Journal of Cell Biology
The small GTPase Rab1 is required for vesicular traffic from the ER to the cis-Golgi compartment, and for transport between the cis and medial compartments of the Golgi stack. In the present study, we examine the role of guanine nucleotide dissociati
Autor:
S. Pind, Adrienne D. Cox, William E. Balch, Channing J. Der, Jeffrey R. Bourne, R. Schwaninger, Helen Plutner, Roya Khosravi-Far
Publikováno v:
The Journal of Cell Biology
We report an essential role for the ras-related small GTP-binding protein rab1b in vesicular transport in mammalian cells. mAbs detect rab1b in both the ER and Golgi compartments. Using an assay which reconstitutes transport between the ER and the ci
Publikováno v:
The EMBO Journal. 9:2375-2383
Synthetic peptides of the putative effector domain of members of the ras-related rab gene family of small GTP-binding proteins were synthesized and found to be potent inhibitors of endoplasmic reticulum (ER) to Golgi and intra-Golgi transport in vitr
Publikováno v:
The Journal of biological chemistry. 269(17)
Deletion of phenylalanine at position 508 (delta F508) in the first nucleotide-binding fold of the cystic fibrosis transmembrane conductance regulator (CFTR) is the most common mutation in patients with cystic fibrosis. Although retaining functional
Autor:
Howard W. Davidson, Helen Plutner, Sandra L. Schmid, Con J M Beckers, R. Schwaninger, William E. Balch, S. Pind
Publisher Summary This chapter focuses on techniques used in the laboratory to reconstitute endoplasmic reticulum (ER)-to-Golgi transport in vitro, using adherent tissue culture cells that have been rendered semiintact by gently scraping them from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65708805affc5849a43b4a02092cb56c
https://doi.org/10.1016/0076-6879(93)21019-5
https://doi.org/10.1016/0076-6879(93)21019-5
Publikováno v:
Methods in enzymology. 221
Autor:
Frank Peter, William E. Balch, Howard W. Davidson, S. Pind, R. Schwaninger, Helen Plutner, Jeffrey R. Bourne, Ellen J. Tisdale
Publikováno v:
Molecular Mechanisms of Membrane Traffic ISBN: 9783662029305
A central problem in cell biology is to understand the molecular basis for the transport of itinerant soluble and membrane-associated macromolecules through multiple compartments of the exocytic and endocytic pathways of eukaryotic cells. Transport i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1ea85c93d4d065a03dd6d8a6768309b
https://doi.org/10.1007/978-3-662-02928-2_3
https://doi.org/10.1007/978-3-662-02928-2_3
Publisher Summary This chapter discusses the transport of protein between endoplasmic reticulum and golgi compartments in semiintact cells. Preparation of cells that actively transport VSV G protein are most thoroughly characterized using CHO cells a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d671ad3990b8d70b0f85d3d110df312
https://doi.org/10.1016/0076-6879(92)19014-w
https://doi.org/10.1016/0076-6879(92)19014-w
Publikováno v:
Methods in enzymology. 219