Concordance, disease progression, and heritability of coeliac disease in Italian twins

Autor: M.G. Limongelli, Luigi Greco, Mara Giordano, Giuseppe Magazzù, Corrado Fagnani, Lorenza Nisticò, Iolanda Coto, Patricia Momigliano-Richiardi, Sandra D'Alfonso, Concettina Sferlazzas, Franco Paparo, Maria Antonietta Stazi, Rodolfo Cotichini, S. Percopo

Publikováno v: Gut. 55:803-808

Background and aims: We adopted the twin method to disentangle the genetic and environmental components of susceptibility to coeliac disease (CD). We estimated disease concordance rate by zygosity and HLA genotypes, discordance times, progression rat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dafd3a3c5983509fb660a2d8a96379f6
https://doi.org/10.1136/gut.2005.083964

The first large population based twin study of coeliac disease

Autor: C. D'Agate, Roberto Tosi, Iolanda Coto, Rodolfo Cotichini, Maria Antonietta Stazi, M.G. Limongelli, S. Percopo, Valeria Gasperi, Lucia Sacchetti, Maria Maglio, Nadia Tinto, Luigi Greco, F. Paparo, N Di Cosmo, R Romino

Publikováno v: Gut 50(5) (2002): 624–628.
info:cnr-pdr/source/autori:Greco L., Romino R., Coto I., Di Cosmo N., Percopo S., Maglio M., Paparo F., Gasperi V., Limongelli M.G., Cotichini R., D'Agate C., Tinto N., Sacchetti L., Tosi R. and Stazi M.A./titolo:The first large population based twin study of coeliac disease/doi:/rivista:Gut/anno:2002/pagina_da:624/pagina_a:628/intervallo_pagine:624–628/volume:50(5)

Background and aims: The genetic load in coeliac disease has hitherto been inferred from case series or anecdotally referred twin pairs. We have evaluated the genetic component in coeliac disease by estimating the concordance rate for the disease amo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2425364ca6f2351b52f325ca9ad68bf
https://doi.org/10.1136/gut.50.5.624

The coeliac disease task force 'Free from Gluten' 'Improved knowledge to cure coeliac disease'

Autor: L Greco, S Percopo

Publikováno v: Acta Paediatrica. 85:25-28

Gluten has recently been introduced into the diet of the Mediterranean and European population, but a considerable proportion has not adapted to this change and has developed intolerance to gluten. At least one million EEC citizens are gluten intoler

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cac518f7822cc6d31d17e028f566403
https://doi.org/10.1111/j.1651-2227.1996.tb14243.x

TheIL12Bgene does not confer susceptibility to coeliac disease

Autor: Lena Samuelsson, Patricia Momigliano-Richiardi, A.S. Louka, Ludvig M. Sollid, J. Ek, S. Percopo, A. H. Gudjonsdottir, Iolanda Coto, Jan Wahlström, Henry Ascher, Sandra D'Alfonso, Marta Mellai, Luigi Greco, Å. Torinsson Naluai, Mara Giordano

Publikováno v: Tissue Antigens. 59:70-72

Coeliac disease (CD) is a chronic inflammatory disorder where dietary gluten is not tolerated. In the lesion there are gluten reactive T cells predominantly secreting gamma-interferon. Both HLA and non-HLA genes contribute to CD susceptibility. Inter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5bd453ceb8ecbf83e17ab14c53e98dca
https://doi.org/10.1034/j.1399-0039.2002.590117.x

Evidence of a correlation between mannose binding lectin and celiac disease: a model for other autoimmune diseases

Autor: Sergio Crovella, V. Baldas, Michele Boniotto, Serena Vatta, Antonio Amoroso, Alessandro Ventura, Oriano Radillo, Francesco Tedesco, Laura Braida, S. Percopo, Tarcisio Not, Marcella Montico

Publikováno v: Journal of molecular medicine (Berlin, Germany). 83(4)

Celiac disease is a multifactorial disorder caused, in genetically susceptible patients, by the ingestion of dietary gluten. Very little is known about the genetic factors, but there is a strong association of two HLA haplotypes (DQ2 or alpha1*05, be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92020ad6878417efc160bddf436832c0
https://pubmed.ncbi.nlm.nih.gov/15645196