Zobrazeno 1 - 10
of 23
pro vyhledávání: '"S, Oguz Kayaalp"'
Autor:
Umit Yasar, Nurten Seringec, Neslihan Dikmenoglu, Melih O. Babaoglu, S. Oguz Kayaalp, Teuta Zoto, Esin Ileri-Gurel, Atilla Bozkurt
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 108:171-176
The constitutive endothelial nitric oxide synthase (eNOS) plays a major role in circulatory homoeostasis and shows genetic polymorphism. eNOS is expressed and functional in blood cells, including erythrocytes. There is limited knowledge about the con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d7b50bd794d371b0bc595bec44a2420
https://doi.org/10.1111/j.1742-7843.2010.00637.x
https://doi.org/10.1111/j.1742-7843.2010.00637.x
Low frequency of defective alleles of cytochrome P450 enzymes 2C19 and 2D6 in the Turkish population
Autor:
Thomas Schröder, S. Oguz Kayaalp, Muradiye Nacak, A. Sükrü Aynacioglu, Christoph Sachse, Ivar Roots, Selim Kortunay, Atilla Bozkurt, Jürgen Brockmöller
Publikováno v:
Clinical Pharmacology & Therapeutics. 66:185-192
Background and Objectives The genetically polymorphic cytochrome P450 enzymes 2C19 (CYP2C19) and 2D6 (CYP2D6) contribute to the metabolism of about 30% of all drugs. For analysis of the ethnic-related differences in drug disposition and as a preparat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5c2e785a5f8958d3417924f3a05d66
https://doi.org/10.1053/cp.1999.v66.100072001
https://doi.org/10.1053/cp.1999.v66.100072001
Autor:
Melih O, Babaoglu, Neslihan, Dikmenoglu, Esin, Ileri-Gurel, Nurten, Seringec, Teuta, Zoto, Umit, Yasar, S Oguz, Kayaalp, Atilla, Bozkurt
Publikováno v:
Basicclinical pharmacologytoxicology. 108(3)
The constitutive endothelial nitric oxide synthase (eNOS) plays a major role in circulatory homoeostasis and shows genetic polymorphism. eNOS is expressed and functional in blood cells, including erythrocytes. There is limited knowledge about the con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::03550e1749d681453ed2b97a137058c6
https://pubmed.ncbi.nlm.nih.gov/20977680
https://pubmed.ncbi.nlm.nih.gov/20977680
Autor:
Guilherme Suarez-Kurtz, Toshiyuki Someya, S. Oguz Kayaalp, Vural Ozdemir, Eugene Kolker, Andrew A. Somogyi, R. Stenne
Applications of omics technologies in the postgenomics era swiftly expanded from rare monogenic disorders to multifactorial common complex diseases, pharmacogenomics, and personalized medicine. Already, there are signposts indicative of further omics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf179c3ebc1fd0797ab7db297c7aab8c
https://europepmc.org/articles/PMC2727354/
https://europepmc.org/articles/PMC2727354/
Autor:
Marja-Liisa Dahl, Mia Sandberg, S. Oguz Kayaalp, Atila Bozkurt, Erik Eliasson, Melih O. Babaoglu, Umit Yasar
Publikováno v:
European journal of clinical pharmacology. 60(5)
Cytochrome P(450) 2C9 (CYP2C9) is a polymorphic enzyme catalysing the metabolism of several important drugs. Losartan has recently been suggested as a selective probe for CYP2C9 metabolic activity. The aim of the study was to determine the activity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7af659a6344bbcfd4290957b742db56
https://pubmed.ncbi.nlm.nih.gov/15197523
https://pubmed.ncbi.nlm.nih.gov/15197523
Publikováno v:
ResearcherID
Debrisoquin hydroxylation polymorphism was studied in 326 unrelated healthy Turkish volunteers. Debrisoquin sulfate (10 mg) was administered to subjects, and debrisoquin and 4-hydroxydebrisoquin were determined in the 0- to 8-hour urine samples. Debr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae23007332488a9216af9e237aabf069
https://doi.org/10.1038/clpt.1994.48
https://doi.org/10.1038/clpt.1994.48
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 27(3)
The aim of this study was to investigate the effects of two antihistaminic drugs, terfenadine and diphenhydramine on CYP2D6 activity by using debrisoquine as a model substrate. The study was carried out as an in vivo single-dose study in 12 young, he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188a1ae9d078849cab5be3d02c73e307
https://pubmed.ncbi.nlm.nih.gov/12365197
https://pubmed.ncbi.nlm.nih.gov/12365197
Publikováno v:
Kortunay, S, Bozkurt, A, Basci, N E, Brøsen, K & Kayaalp, S O 2001, ' Dose-dependent inhibition of the CYP2D6 catalyzed oxidation of sparteine by mepyramine in healthy volunteers ', Pharmacology and Toxicology, vol. 89, no. 6, pp. 331-334 . https://doi.org/10.1034/j.1600-0773.2001.d01-170.x
Not Available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3876c444e92c64835473a798d1609a7
https://pubmed.ncbi.nlm.nih.gov/11903961
https://pubmed.ncbi.nlm.nih.gov/11903961
Autor:
F, Oztürk, S, Kortunay, E, Kurt, U, Ubeyt Inan, S, Sami Ilker, N E, Basci, A, Bozkurt, S, Oguz Kayaalp
Publikováno v:
Ophthalmic research. 31(6)
This study was carried out to get an insight into the ofloxacin elimination after intravitreal injection in rabbits. We also studied the effects of trauma and inflammation on the vitreous ofloxacin levels after intravitreal injection of ofloxacin.A p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a364d1f8d0f38e4e3b4ce4f5cc787187
https://pubmed.ncbi.nlm.nih.gov/10474074
https://pubmed.ncbi.nlm.nih.gov/10474074
Publikováno v:
Life sciences. 61(22)
The effects of NG-nitro arginine methyl ester (L-NAME) and 7-nitroindazole (7-NI), nitric oxide synthase inhibitors, and L-arginine, a nitric oxide precursor, on ethanol withdrawal signs were investigated in rats. Ethanol (7.2% v v ) was given to rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad1242214da94cb4c6e112c18118aa7
https://pubmed.ncbi.nlm.nih.gov/9393939
https://pubmed.ncbi.nlm.nih.gov/9393939