Zobrazeno 1 - 10
of 274
pro vyhledávání: '"S, Nord"'
Autor:
Timothy A. Fenton, Olivia Y. Haouchine, Elizabeth B. Hallam, Emily M. Smith, Kiya C. Jackson, Darlene Rahbarian, Cesar P. Canales, Anna Adhikari, Alex S. Nord, Roy Ben-Shalom, Jill L. Silverman
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Disruption of SYNGAP1 directly causes a genetically identifiable neurodevelopmental disorder (NDD) called SYNGAP1-related intellectual disability (SRID). Without functional SynGAP1 protein, individuals are developmentally delayed and have pr
Externí odkaz:
https://doaj.org/article/342ace3d29f742d2bb545fc65e6bb4f1
Autor:
Jacob H. Wilmot, Tracy L. Warren, Cassiano R. A. F. Diniz, Deger Carda, Marrisa M. Lafreniere, Alex S. Nord, Brian J. Wiltgen
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 18 (2024)
Molecular and genetic techniques now allow selective tagging and manipulation of the population of neurons, often referred to as “engram cells,” that were active during a specific experience. One common approach to labeling these cells is to use
Externí odkaz:
https://doaj.org/article/c9e8fa8b73cf42868745234d895078dd
Autor:
Siavash Fazel Darbandi, Joon-Yong An, Kenneth Lim, Nicholas F. Page, Lindsay Liang, David M. Young, Athena R. Ypsilanti, Matthew W. State, Alex S. Nord, Stephan J. Sanders, John L.R. Rubenstein
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114329- (2024)
Summary: Many autism spectrum disorder (ASD)-associated genes act as transcriptional regulators (TRs). Chromatin immunoprecipitation sequencing (ChIP-seq) was used to identify the regulatory targets of ARID1B, BCL11A, FOXP1, TBR1, and TCF7L2, ASD-ass
Externí odkaz:
https://doaj.org/article/96b97b7930204f6ea8932076d915ef71
Publikováno v:
Brazilian Journal of Otorhinolaryngology, Vol 88, Iss 5, Pp 817-820 (2022)
Externí odkaz:
https://doaj.org/article/aa8bf5d15de64a13a3bb786f5ac86c1d
Autor:
Rinaldo Catta-Preta, Iva Zdilar, Bradley Jenner, Emily T. Doisy, Kayleen Tercovich, Alex S. Nord, Gene G. Gurkoff
Publikováno v:
Neurotrauma Reports, Vol 2, Iss 1, Pp 512-525 (2021)
Traumatic brain injury (TBI) causes acute and lasting impacts on the brain, driving pathology along anatomical, cellular, and behavioral dimensions. Rodent models offer an opportunity to study the temporal progression of disease from injury to recove
Externí odkaz:
https://doaj.org/article/4b6de5928e794e99a731f67c46d51311
Autor:
Jessica L. Haigh, Anna Adhikari, Nycole A. Copping, Tyler Stradleigh, A. Ayanna Wade, Rinaldo Catta-Preta, Linda Su-Feher, Iva Zdilar, Sarah Morse, Timothy A. Fenton, Anh Nguyen, Diana Quintero, Samrawit Agezew, Michael Sramek, Ellie J. Kreun, Jasmine Carter, Andrea Gompers, Jason T. Lambert, Cesar P. Canales, Len A. Pennacchio, Axel Visel, Diane E. Dickel, Jill L. Silverman, Alex S. Nord
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-22 (2021)
Abstract Background Genes with multiple co-active promoters appear common in brain, yet little is known about functional requirements for these potentially redundant genomic regulatory elements. SCN1A, which encodes the NaV1.1 sodium channel alpha su
Externí odkaz:
https://doaj.org/article/78fe0a2d5b104a109781adedaf6df4e5
Autor:
J. Ellegood, S. P. Petkova, A. Kinman, L. R. Qiu, A. Adhikari, A. A. Wade, D. Fernandes, Z. Lindenmaier, A. Creighton, L. M. J. Nutter, A. S. Nord, J. L. Silverman, J. P. Lerch
Publikováno v:
Molecular Autism, Vol 12, Iss 1, Pp 1-24 (2021)
Abstract Background One of the causal mechanisms underlying neurodevelopmental disorders (NDDs) is chromatin modification and the genes that regulate chromatin. AT-rich interactive domain 1B (ARID1B), a chromatin modifier, has been linked to autism s
Externí odkaz:
https://doaj.org/article/0fe323d806e84f1b82cf980dfb9bea70
Autor:
Matthew S. Nord, Cyril Bernis, Sarah Carmona, Dennis C. Garland, Anna Travesa, Douglass J. Forbes
Publikováno v:
Nucleus, Vol 11, Iss 1, Pp 178-193 (2020)
Xenopus egg extracts are a powerful in vitro tool for studying complex biological processes, including nuclear reconstitution, nuclear membrane and pore assembly, and spindle assembly. Extracts have been further used to demonstrate a moonlighting reg
Externí odkaz:
https://doaj.org/article/d16cb22ca3d94f26ade2b96123e4c8f6
Autor:
A. Ayanna Wade, Jelle van den Ameele, Seth W. Cheetham, Rebecca Yakob, Andrea H. Brand, Alex S. Nord
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103234- (2021)
Summary: Genetic studies of autism have revealed causal roles for chromatin remodeling gene mutations. Chromodomain helicase DNA binding protein 8 (CHD8) encodes a chromatin remodeler with significant de novo mutation rates in sporadic autism. Howeve
Externí odkaz:
https://doaj.org/article/4d31afdb8ce6460180b433cbe96604ab
Publikováno v:
OTO Open, Vol 5 (2021)
Objective Postoperative complication rates were compared between obstructive sleep apnea surgery (OSAS) and hypoglossal nerve upper airway stimulation (UAS). Study Design Cohort. Setting Multi-institutional international databases. Methods OSAS data
Externí odkaz:
https://doaj.org/article/416f966f23224fba8d814361a928be51