Zobrazeno 1 - 10
of 2 027
pro vyhledávání: '"S, Noble"'
Autor:
Vianne R. Gao, Rui Yang, Arnav Das, Renhe Luo, Hanzhi Luo, Dylan R. McNally, Ioannis Karagiannidis, Martin A. Rivas, Zhong-Min Wang, Darko Barisic, Alireza Karbalayghareh, Wilfred Wong, Yingqian A. Zhan, Christopher R. Chin, William S. Noble, Jeff A. Bilmes, Effie Apostolou, Michael G. Kharas, Wendy Béguelin, Aaron D. Viny, Danwei Huangfu, Alexander Y. Rudensky, Ari M. Melnick, Christina S. Leslie
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Identifying cell-type-specific 3D chromatin interactions between regulatory elements can help decipher gene regulation and interpret disease-associated non-coding variants. However, achieving this resolution with current 3D genomics technolo
Externí odkaz:
https://doaj.org/article/9058f5eecd4a4599ae65bc3feace0303
Autor:
Robin Aguilar, Conor K. Camplisson, Qiaoyi Lin, Karen H. Miga, William S. Noble, Brian J. Beliveau
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Fluorescent in situ hybridization (FISH) is a powerful method for the targeted visualization of nucleic acids in their native contexts. Recent technological advances have leveraged computationally designed oligonucleotide (oligo) probes to i
Externí odkaz:
https://doaj.org/article/11b986022f7646e6b02f240607074f00
Publikováno v:
Ceylon Journal of Science, Vol 52, Iss 2, Pp 127-131 (2023)
Vector surveillance is crucial for implementation of appropriate vector control strategies to reduce the transmission of vector-borne diseases such as dengue, a major public health concern in Sri Lanka. Aedes aegypti and Ae. albopictus are the primar
Externí odkaz:
https://doaj.org/article/3def384a67f749cb8ac564e6b2628dbd
Autor:
Rui Yang, Arnav Das, Vianne R. Gao, Alireza Karbalayghareh, William S. Noble, Jeffrey A. Bilmes, Christina S. Leslie
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-26 (2023)
Abstract Recent deep learning models that predict the Hi-C contact map from DNA sequence achieve promising accuracy but cannot generalize to new cell types and or even capture differences among training cell types. We propose Epiphany, a neural netwo
Externí odkaz:
https://doaj.org/article/03e9075f1972485484f1aafb6af44eb5
Autor:
Rui Yang, Arnav Das, Vianne R. Gao, Alireza Karbalayghareh, William S. Noble, Jeffrey A. Bilmes, Christina S. Leslie
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/9e27b8675a2a42da9d2482ac953dcd45
Dynamic chromatin organization and regulatory interactions in human endothelial cell differentiation
Autor:
Kris G. Alavattam, Katie A. Mitzelfelt, Giancarlo Bonora, Paul A. Fields, Xiulan Yang, Han Sheng Chiu, Lil Pabon, Alessandro Bertero, Nathan J. Palpant, William S. Noble, Charles E. Murry
Publikováno v:
Stem Cell Reports, Vol 18, Iss 1, Pp 159-174 (2023)
Summary: Vascular endothelial cells are a mesoderm-derived lineage with many essential functions, including angiogenesis and coagulation. The gene-regulatory mechanisms underpinning endothelial specialization are largely unknown, as are the roles of
Externí odkaz:
https://doaj.org/article/5f7f366be7be4a3e89f754bffcd612c1
Autor:
L. Clark, B. Fitzgerald, S. Noble, S. MacNeill, S. Paramasivan, N. Cotterill, H. Hashim, S. Jha, P. Toozs-Hobson, T. Greenwell, N. Thiruchelvam, W. Agur, A. White, V. Garner, M. Cobos-Arrivabene, C. Clement, M. Cochrane, Y. Liu, A. L. Lewis, J. Taylor, J. A. Lane, M. J. Drake, C. Pope
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-23 (2022)
Abstract Background Women with stress urinary incontinence (SUI) experience urine leakage with physical activity. Currently, the interventional treatments for SUI are surgical, or endoscopic bulking injection(s). However, these procedures are not alw
Externí odkaz:
https://doaj.org/article/2df96f36a18d4d6eb2dbcc5a8de6e905
Publikováno v:
Multimodal Transportation, Vol 2, Iss 1, Pp 100051- (2023)
Free mode choice, termed “synchromodality,” is an extension of intermodal service network design and is still in the early stages of modeling development. European countries have already started moving toward realizing this innovative transportat
Externí odkaz:
https://doaj.org/article/88bfc8db7a2f45368bb3dcfe262ac427
Autor:
M. Drake, J. Worthington, J. Frost, E. Sanderson, N. Cotterill, M. Fader, H. Hashim, M. Macaulay, J. Rees, L. Robles, G. Taylor, J. Taylor, M. Ridd, S. Macneill, S. Noble, A. Lane
Publikováno v:
European Urology Open Science, Vol 48, Iss , Pp S26- (2023)
Externí odkaz:
https://doaj.org/article/1df039d5ae014fbf86fc6d2c61485344
Autor:
Giancarlo Bonora, Vijay Ramani, Ritambhara Singh, He Fang, Dana L. Jackson, Sanjay Srivatsan, Ruolan Qiu, Choli Lee, Cole Trapnell, Jay Shendure, Zhijun Duan, Xinxian Deng, William S. Noble, Christine M. Disteche
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-36 (2021)
Abstract Background Mammalian development is associated with extensive changes in gene expression, chromatin accessibility, and nuclear structure. Here, we follow such changes associated with mouse embryonic stem cell differentiation and X inactivati
Externí odkaz:
https://doaj.org/article/2c9de6e28d644156acdf2680b105da84