Zobrazeno 1 - 10
of 215
pro vyhledávání: '"S, Nakajin"'
Autor:
S Nakajin, Masatada Watanabe
Publikováno v:
Journal of Endocrinology. 180:125-133
A number of conditions related to sex-reversal in boys and men and precocious puberty in girls are caused by estrogen-secreting adrenal tumors. In these tumors, cytochrome P450 aromatase (aromatase) that is encoded in the CYP19 gene is expressed at h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12803d91551b4440929035e1f0934345
https://doi.org/10.1677/joe.0.1800125
https://doi.org/10.1677/joe.0.1800125
Publikováno v:
Journal of molecular endocrinology. 32(2)
A number of clinical studies have highlighted the importance of estrogen in bone growth and maintenance in men and postmenopausal women. In these instances, estrogen is synthesized locally within bone tissue by aromatase, encoded by the CYP19 gene. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8bfe62d521e2e7a404fcd2fc051cd68
https://pubmed.ncbi.nlm.nih.gov/15072557
https://pubmed.ncbi.nlm.nih.gov/15072557
Publikováno v:
The Journal of biological chemistry. 276(21)
Porcine testicular carbonyl reductase (PTCR) belongs to the short chain dehydrogenases/reductases (SDR) superfamily and catalyzes the NADPH-dependent reduction of ketones on steroids and prostaglandins. The enzyme shares nearly 85% sequence identity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2a3ff3010c7a5174613d66872f654e3
https://pubmed.ncbi.nlm.nih.gov/11279087
https://pubmed.ncbi.nlm.nih.gov/11279087
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 54(5-6)
The cDNA coding for pig testicular 3 alpha/beta (20 beta)-hydroxysteroid dehydrogenase was expressed in Escherichia coli by placing it under the control of an isopropylthiogalactoside (IPTG) inducible tac promoter. Production of 3 alpha/beta (20 beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2112a0122a6cf9a34f5ce39fa48055be
https://pubmed.ncbi.nlm.nih.gov/7577708
https://pubmed.ncbi.nlm.nih.gov/7577708
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 42(1)
Three enzymatic activities (3 alpha/beta-hydroxysteroid dehydrogenase, 20 beta- and 20 alpha-hydroxysteroid dehydrogenases) were measured in testes of pigs as a function of age. Earlier studies reported a highly purified 20 beta-hydroxysteroid dehydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec07b95e1350d7c4c008acd94f5d033b
https://pubmed.ncbi.nlm.nih.gov/1558817
https://pubmed.ncbi.nlm.nih.gov/1558817
Autor:
M Watanabe, S Nakajin
Publikováno v:
Journal of Endocrinology; Jan2004, Vol. 180 Issue 1, p125-133, 9p
Publikováno v:
Acta Crystallographica Section A Foundations of Crystallography. 49:c109-c109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edb968a5e2ab79a6aec23bdbc473cc5c
https://doi.org/10.1107/s0108767378096853
https://doi.org/10.1107/s0108767378096853
Publikováno v:
Journal of Biological Chemistry. 256:6134-6139
Kinetic and binding studies were performed with a purified microsomal cytochrome P-450 from neonatal pig testis, the C21 side chain cleavage system (17 alpha-hydroxylase/C17,20-lyase). Binding of substrates and inhibitors was measured by spectral met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cfba51e7088a2df2862d2c5e1e7b1e5
https://doi.org/10.1016/s0021-9258(19)69138-6
https://doi.org/10.1016/s0021-9258(19)69138-6
Publikováno v:
Nihon Naibunpi Gakkai zasshi. 51(1)
To develop the prophylactics and the curatives for atherosclerosis, thyroxine derivative, CG-635, was assayed for its physiological activities in experimental atherosclerosis in rabbits fed with cholesterol. It was found that CG-635 possessed serum T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8fe8849aaa515e45c9508bb2c8b4118c
https://pubmed.ncbi.nlm.nih.gov/1171031
https://pubmed.ncbi.nlm.nih.gov/1171031
Publikováno v:
Journal of steroid biochemistry. 33(6)
Two distinct molecules of 20 alpha-hydroxysteroid dehydrogenase (20 alpha-HSD) from pig adrenal cytosol have been purified to homogeneity and characterized. Purification was achieved by ammonium sulphate precipitation followed by DEAE-cellulose colum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d16b23465fc7a25245036bec6b3ff475
https://pubmed.ncbi.nlm.nih.gov/2615363
https://pubmed.ncbi.nlm.nih.gov/2615363