Zobrazeno 1 - 10
of 509
pro vyhledávání: '"S, McNeill"'
Autor:
Marla I Hertz, Ashley S McNeill
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 11, p e1012604 (2024)
Externí odkaz:
https://doaj.org/article/15224d66501c48a5bb83d4233932e6a0
The first book-length treatment of Utah's distinctive food heritage, this volume contains work by more than sixty subject-matter experts, including scholars, community members, event organizers, journalists, bloggers, photographers, and food producer
Autor:
Trevor J. Blank, Lynne S. McNeill
The essays in this volume explore the menacing figure of Slender Man—the blank-faced, long-limbed bogeyman born of a 2009 Photoshop contest who has appeared in countless horror stories circulated on- and offline among children and young people. Sle
Autor:
Mollie S. Schubert, Bernice Thommandru, Jessica Woodley, Rolf Turk, Shuqi Yan, Gavin Kurgan, Matthew S. McNeill, Garrett R. Rettig
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract CRISPR–Cas proteins are RNA-guided nucleases used to introduce double-stranded breaks (DSBs) at targeted genomic loci. DSBs are repaired by endogenous cellular pathways such as non-homologous end joining (NHEJ) and homology-directed repair
Externí odkaz:
https://doaj.org/article/beb41c1f9a884d0690dce2597cdadd0e
Autor:
Gavin Kurgan, Rolf Turk, Heng Li, Nathan Roberts, Garrett R. Rettig, Ashley M. Jacobi, Lauren Tso, Morgan Sturgeon, Massimo Mertens, Roel Noten, Kurt Florus, Mark A. Behlke, Yu Wang, Matthew S. McNeill
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 478-491 (2021)
CRISPR systems enable targeted genome editing in a wide variety of organisms by introducing single- or double-strand DNA breaks, which are repaired using endogenous molecular pathways. Characterization of on- and off-target editing events from CRISPR
Externí odkaz:
https://doaj.org/article/5e209aed7e8a4ef2be494827ee71b257
Autor:
Liyang Zhang, John A. Zuris, Ramya Viswanathan, Jasmine N. Edelstein, Rolf Turk, Bernice Thommandru, H. Tomas Rube, Steve E. Glenn, Michael A. Collingwood, Nicole M. Bode, Sarah F. Beaudoin, Swarali Lele, Sean N. Scott, Kevin M. Wasko, Steven Sexton, Christopher M. Borges, Mollie S. Schubert, Gavin L. Kurgan, Matthew S. McNeill, Cecilia A. Fernandez, Vic E. Myer, Richard A. Morgan, Mark A. Behlke, Christopher A. Vakulskas
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The utility of AsCas12a can be limited to poor editing efficiency. Here the authors identify a variant, “AsCas12a Ultra”, that has high on-target specificity demonstrated through editing of clinically relevant T cell genes.
Externí odkaz:
https://doaj.org/article/0168163683a24415a8a5f32e5a19e09a
Autor:
Ido Amit, Ortal Iancu, Alona Levy-Jurgenson, Gavin Kurgan, Matthew S. McNeill, Garrett R. Rettig, Daniel Allen, Dor Breier, Nimrod Ben Haim, Yu Wang, Leon Anavy, Ayal Hendel, Zohar Yakhini
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The control of off-target activity is a challenge for adapting CRISPR to therapeutic use. Here the authors present CRISPECTOR, a software tool to detect, evaluate and quantify editing activity, including translocations, from NGS data.
Externí odkaz:
https://doaj.org/article/a5eef4e669634506b9f9db24ef9fe0fe
Autor:
Jenny Shapiro, Ortal Iancu, Ashley M. Jacobi, Matthew S. McNeill, Rolf Turk, Garrett R. Rettig, Ido Amit, Adi Tovin-Recht, Zohar Yakhini, Mark A. Behlke, Ayal Hendel
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 1097-1107 (2020)
Genome editing of human cluster of differentiation 34+ (CD34+) hematopoietic stem and progenitor cells (HSPCs) holds great therapeutic potential. This study aimed to optimize on-target, ex vivo genome editing using the CRISPR-Cas9 system in CD34+ HSP
Externí odkaz:
https://doaj.org/article/74189cca19364566b5cb4597df8b7115
Publikováno v:
Recycling, Vol 7, Iss 4, p 53 (2022)
Increased fashion consumption spurred by fast fashion has led to excessive textile waste, giving rise to a global crisis as textile waste pollutes land and waterways, while landfill and incineration contribute to global greenhouse gas emissions. Exte
Externí odkaz:
https://doaj.org/article/6f6984f0514144dbbaf0043197756c59
Publikováno v:
Atmospheric Measurement Techniques, Vol 11, Pp 1901-1920 (2018)
A chemical ionization mass spectrometry (CIMS) method utilizing a reagent gas mixture of O2, CO2, and CH3I in N2 is described and optimized for quantitative gas-phase measurements of hydrogen peroxide (H2O2), methyl peroxide (CH3OOH), formic acid
Externí odkaz:
https://doaj.org/article/501ca51094f046de805e66866f596136