Zobrazeno 1 - 10
of 95
pro vyhledávání: '"S, Kuchen"'
Publikováno v:
Differenzialdiagnose rheumatischer Erkrankungen ISBN: 9783662565742
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b09997e2b9611c0d414bc4080d6daa8
https://doi.org/10.1007/978-3-662-56575-9_10
https://doi.org/10.1007/978-3-662-56575-9_10
Autor:
J Schedel, C A Seemayer, T Pap, M Neidhart, S Kuchen, B A Michel, R E Gay, U Müller-Ladner, S Gay, W Zacharias
Publikováno v:
Gene Therapy. 11:1040-1047
The present study was undertaken to examine whether ribozymes cleaving specifically cathepsin L (CL) mRNA are able to decrease the synthesis of CL protease in rheumatoid arthritis synovial fibroblasts (RA-SF) and thereby reduce the invasiveness into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10df379eaf9389af2489e0adde8d85c5
https://doi.org/10.1038/sj.gt.3302265
https://doi.org/10.1038/sj.gt.3302265
Autor:
C. A. Seemayer, O. Distler, S. Kuchen, U. Müller-Ladner, B. A. Michel, M. Neidhart, R. E. Gay, S. Gay
Publikováno v:
Zeitschrift f�r Rheumatologie. 60:309-318
Rheumatoid arthritis (RA) is a chronic inflammatory disease, which is mainly characterized by synovial hyperplasia, pathological immune phenomena and progressive destruction of the affected joints. Various cell types are involved in the pathogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c2a5331deecc8c1febec24ffbbf09e5
https://doi.org/10.1007/s003930170030
https://doi.org/10.1007/s003930170030
Publikováno v:
Annals of the rheumatic diseases. 67
Interleukin 21 (IL21) belongs to a family of cytokines that bind to a composite receptor consisting of a private receptor (IL21R) and the common cytokine receptor gamma chain (gamma(C)). The IL21R is widely distributed on lympho-haematopoietic cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ae63dfacadb8f03e01ad1969fa21c3
https://pubmed.ncbi.nlm.nih.gov/19022821
https://pubmed.ncbi.nlm.nih.gov/19022821
Autor:
C A, Seemayer, S, Kuchen, M, Neidhart, P, Kuenzler, V, Rihosková, E, Neumann, M, Pruschy, W K, Aicher, U, Müller-Ladner, R E, Gay, B A, Michel, G S, Firestein, S, Gay
Publikováno v:
Annals of the rheumatic diseases. 62(12)
Objective: To analyse the functional response of p53 in rheumatoid arthritis synovial fibroblasts (RASF) in vitro and in vivo and to investigate whether activation of p53 modulates the destructive process of RASF. Methods: RASF and controls grown on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4220c050fa8c05b49bdb2f17fdefee75
https://pubmed.ncbi.nlm.nih.gov/14644850
https://pubmed.ncbi.nlm.nih.gov/14644850
Autor:
C A, Seemayer, O, Distler, S, Kuchen, U, Müller-Ladner, B A, Michel, M, Neidhart, R E, Gay, S, Gay
Publikováno v:
Zeitschrift fur Rheumatologie. 60(5)
Rheumatoid arthritis (RA) is a chronic inflammatory disease, which is mainly characterized by synovial hyperplasia, pathological immune phenomena and progressive destruction of the affected joints. Various cell types are involved in the pathogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a004ec4b57497c61dd091b7c35c3438
https://pubmed.ncbi.nlm.nih.gov/11759230
https://pubmed.ncbi.nlm.nih.gov/11759230
Autor:
CA Seemayer, S Kuchen, M Neihart, P Kuenzler, E Neumann, M Pruschy, T Pap, WK Aicher, U Muller-Ladner, BA Michel, RE Gay, S Gay
Publikováno v:
Speaker abstracts 2001.
Background Objectives The aim of this study was to investigate, whether the destructive process of synovial fibroblasts in rheumatoid arthritis is dependent on the expression of p53. Moreover, we searched for the expression of p53 in RA-SF in vitro a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8194f7e2ee23af9144f92e6bafb2a86c
https://doi.org/10.1136/annrheumdis-2001.986
https://doi.org/10.1136/annrheumdis-2001.986
Publikováno v:
Speaker abstracts 2001.
Background The progression of the cell cycle is tightly controlled by cyclins and cyclin-dependent kinases. The p16Ink4a protein was identified as a specific inhibitor of cdk4. P16 inhibits the cdk4-dependent phosphorylation of the tumour suppressor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0b5e8257b6e141aefa0204b07858ca0
https://doi.org/10.1136/annrheumdis-2001.981
https://doi.org/10.1136/annrheumdis-2001.981
Autor:
J Tomasova Studynkova, S Kuchen, E Jeisy, J Schedel, F Charvat, K Jarosova, R Gay, H Sprott, J Vencovsky, S Gay
Publikováno v:
Speaker abstracts 2001.
Background Objectives To investigate pathogenesis of inflammation in muscles of patients with idiopathic inflammatory myopathies (IIM) – dermatomyositis (DM), polymyositis (PM) by studying expression of cox, lox and neuropeptides, using in situ hyb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e77bd86617e354a9e2bf08c50a583cc8
https://doi.org/10.1136/annrheumdis-2001.840
https://doi.org/10.1136/annrheumdis-2001.840
Publikováno v:
Arthritis and rheumatism. 42(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de4a81734b03b0d68907096847fc6ee7
https://pubmed.ncbi.nlm.nih.gov/10025936
https://pubmed.ncbi.nlm.nih.gov/10025936