Zobrazeno 1 - 10
of 76
pro vyhledávání: '"S, Kirakodu"'
Publikováno v:
Frontiers in Oral Health, Vol 4 (2023)
IntroductionPeriodontitis is delineated by a dysbiotic microbiome at sites of lesions accompanied by a dysregulated persistent inflammatory response that undermines the integrity of the periodontium. The interplay of the altered microbial ecology and
Externí odkaz:
https://doaj.org/article/f3110940e34d49859ba8b3d2ad928bdf
Publikováno v:
Clinical and Experimental Immunology. 211:248-268
Phenotypic and functional heterogeneity of macrophages is clearly a critical component of their effective functions in innate and adaptive immunity. This investigation hypothesized that altered profiles of gene expression in gingival tissues in healt
Autor:
Jeffrey L. Ebersole, Sreenatha S. Kirakodu, Elliot Neumann, Luis Orraca, Janis Gonzalez Martinez, Octavio A. Gonzalez
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Objective: This study focused on documenting characteristics of the gingival transcriptome during various stages of periodontitis targeting genes associated with apoptotic and autophagic pathways and changes that specifically associate with features
Externí odkaz:
https://doaj.org/article/7a2588aa159b448fb5eb514ae346991e
Publikováno v:
Journal of Periodontology.
Akademický článek
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Autor:
Jeffrey L Ebersole, Sreenatha S Kirakodu, M. John Novak, Luis Orraca, Larry L Cunningham, Mark V Thomas, Arnold Stromberg, Subramanya N Pandruvada, Janis Gonzalez Martinez
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Evidence has shown activation of T and B cells in gingival tissues in experimental models and in humans diagnosed with periodontitis. The results of this adaptive immune response are noted both locally and systemically with antigenic specificity for
Externí odkaz:
https://doaj.org/article/aceec01fa4914dc6b20f7823c8281130
Publikováno v:
Molecular immunology. 148
Colonization of mucosal tissues throughout the body occurs by a wide array of bacteria in the microbiome that stimulate the cells and tissues, as well as respond to changes in the local milieu. A feature of periodontitis is the detection of adaptive
Supplemental material, DS_10.1177_0022034520906138 for Oral Microbiome and Gingival Transcriptome Profiles of Ligature-Induced Periodontitis by J. Ebersole, S. Kirakodu, J. Chen, R. Nagarajan and O.A. Gonzalez in Journal of Dental Research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76d521c5c34de2c5c827bdf5337782b
Akademický článek
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Publikováno v:
Advances in experimental medicine and biology. 1197
Epithelial cells and functions of the epithelium are critical to the health of the oral cavity. We used a nonhuman primate model to profile the transcriptome of gingival tissues in health across the lifespan and hypothesized that in older animals, ep