Zobrazeno 1 - 10
of 1 137
pro vyhledávání: '"S, Kaminski"'
Autor:
Ward, Edward N., McClelland, Rebecca M., Lamb, Jacob R., Rubio-Sánchez, Roger, Christensen, Charles N., Mazumder, Bismoy, Kapsiani, Sofia, Mascheroni, Luca, Di Michele, Lorenzo, Schierle, Gabriele S. Kaminski, Kaminski, Clemens F.
Structured illumination can reject out-of-focus signal from a sample, enabling high-speed and high-contrast imaging over large areas with widefield detection optics. Currently, this optical-sectioning technique is limited by image reconstruction arte
Externí odkaz:
http://arxiv.org/abs/2311.00089
Autor:
Meng Lu, Ernestine Hui, Marius Brockhoff, Jakob Träuble, Ana Fernandez‐Villegas, Oliver J Burton, Jacob Lamb, Edward Ward, Philippa J Woodhams, Wadood Tadbier, Nino F Läubli, Stephan Hofmann, Clemens F Kaminski, Antonio Lombardo, Gabriele S Kaminski Schierle
Publikováno v:
Advanced Science, Vol 11, Iss 44, Pp n/a-n/a (2024)
Abstract Simultaneously recording network activity and ultrastructural changes of the synapse is essential for advancing understanding of the basis of neuronal functions. However, the rapid millisecond‐scale fluctuations in neuronal activity and th
Externí odkaz:
https://doaj.org/article/6998b4607d234c0ebee01bcdbb3364c2
Autor:
Ward, Edward N., Hecker, Lisa, Christensen, Charles N., Lamb, Jacob R, Lu, Meng, Mascheroni, Luca, Chung, Chyi Wei, Wang, Anna, Rowlands, Christopher J., Schierle, Gabriele S. Kaminski, Kaminski, Clemens F.
Sub-diffraction resolution, gentle sample illumination, and the possibility to image in multiple colors make Structured Illumination Microscopy (SIM) an imaging technique which is particularly well suited for live cell observations. Here, we present
Externí odkaz:
http://arxiv.org/abs/2206.00532
Autor:
Zixuan Lu, Chiara Barberio, Ana Fernandez‐Villegas, Aimee Withers, Alexandra Wheeler, Konstantinos Kallitsis, Eleonora Martinelli, Achilleas Savva, Becky M. Hess, Anna‐Maria Pappa, Gabriele S. Kaminski Schierle, Róisín M. Owens
Publikováno v:
Advanced Science, Vol 11, Iss 27, Pp n/a-n/a (2024)
Abstract Drug studies targeting neuronal ion channels are crucial to understand neuronal function and develop therapies for neurological diseases. The traditional method to study neuronal ion‐channel activities heavily relies on the whole‐cell pa
Externí odkaz:
https://doaj.org/article/096d55a692a94d6ea7e3e0a09313df3a
Autor:
Gonzalo Díaz Mirón, Jonathan A. Semelak, Luca Grisanti, Alex Rodriguez, Irene Conti, Martina Stella, Jayaramakrishnan Velusamy, Nicola Seriani, Nadja Došlić, Ivan Rivalta, Marco Garavelli, Dario A. Estrin, Gabriele S. Kaminski Schierle, Mariano C. González Lebrero, Ali Hassanali, Uriel N. Morzan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Challenging the basis of our chemical intuition, recent experimental evidence reveals the presence of a new type of intrinsic fluorescence in biomolecules that exists even in the absence of aromatic or electronically conjugated chemical comp
Externí odkaz:
https://doaj.org/article/4bd339f5319f46e9b865bb05545ddf7c
Autor:
Joachim De Jonghe, Tomasz S. Kaminski, David B. Morse, Marcin Tabaka, Anna L. Ellermann, Timo N. Kohler, Gianluca Amadei, Charlotte E. Handford, Gregory M. Findlay, Magdalena Zernicka-Goetz, Sarah A. Teichmann, Florian Hollfelder
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Droplet microfluidic methods have massively increased the throughput of single-cell sequencing campaigns. The benefit of scale-up is, however, accompanied by increased background noise when processing challenging samples and the overall RNA
Externí odkaz:
https://doaj.org/article/2dff37ca2c9b446281d0fc46cf2e490a
Akademický článek
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Autor:
Amberley D. Stephens, Ana Fernandez Villegas, Chyi Wei Chung, Oliver Vanderpoorten, Dorothea Pinotsi, Ioanna Mela, Edward Ward, Thomas M. McCoy, Robert Cubitt, Alexander F. Routh, Clemens F. Kaminski, Gabriele S. Kaminski Schierle
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Monomeric alpha-synuclein (aSyn) is a well characterised protein that importantly binds to lipids. aSyn monomers assemble into amyloid fibrils which are localised to lipids and organelles in insoluble structures found in Parkinson’s diseas
Externí odkaz:
https://doaj.org/article/47a85327169c4aaf9bffa1e9000eb692
Autor:
Edward N. Ward, Lisa Hecker, Charles N. Christensen, Jacob R. Lamb, Meng Lu, Luca Mascheroni, Chyi Wei Chung, Anna Wang, Christopher J. Rowlands, Gabriele S. Kaminski Schierle, Clemens F. Kaminski
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Structured Illumination Microscopy allows for the visualization of biological structures at resolutions below the diffraction limit, but this imaging modality is still hampered by high experimental complexity. Here, the authors present a combination
Externí odkaz:
https://doaj.org/article/66f1b12be34640339d1e4a7bd953ad1d
Vector redesign and in‐droplet cell‐growth improves enrichment and recovery in live Escherichia coli
Autor:
Bernard D. G. Eenink, Tomasz S. Kaminski, Erich Bornberg‐Bauer, Joachim Jose, Florian Hollfelder, Bert vanLoo
Publikováno v:
Microbial Biotechnology, Vol 15, Iss 11, Pp 2845-2853 (2022)
Abstract Directed evolution (DE) is a widely used method for improving the function of biomolecules via multiple rounds of mutation and selection. Microfluidic droplets have emerged as an important means to screen the large libraries needed for DE, b
Externí odkaz:
https://doaj.org/article/c4f747cc27c4473aa52f5ceedc1452df