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Comparative Effects of Di( n -Butyl) Phthalate Exposure on Fetal Germ Cell Development in the Rat and in Human Fetal Testis Xenografts

Autor: Richard A. Anderson, Laura Kennedy, Chris McKinnell, Matthew S. Jobling, Ana Calarrao, Sander van den Driesche, Rod T. Mitchell, Richard M. Sharpe, Gary R. Hutchison, Lenka Hrabalkova, Sheila Macpherson

Publikováno v: van den Driesche, S, McKinnell, C, Calarrão, A, Kennedy, L, Hutchison, G R, Hrabalkova, L, Jobling, M S, Macpherson, S, Anderson, R A, Sharpe, R M & Mitchell, R T 2015, ' Comparative Effects of Di(n-Butyl) Phthalate Exposure on Fetal Germ Cell Development in the Rat and in Human Fetal Testis Xenografts ', Environmental Health Perspectives . https://doi.org/10.1289/ehp.1408248
Environmental Health Perspectives

Background Phthalate exposure induces germ cell effects in the fetal rat testis. Although experimental models have shown that the human fetal testis is insensitive to the steroidogenic effects of phthalates, the effects on germ cells have been less e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8284b1d03703287da07e1e048ad22e9
https://doi.org/10.1289/ehp.1408248

Oxidative stress and male reproductive health

Autor: Mark Baker, Matthew S. Jobling, Robert John Aitken, T. B. Smith, Geoffrey N. De Iuliis

Publikováno v: Asian Journal of Andrology, Vol 16, Iss 1, Pp 31-38 (2014)
Asian Journal of Andrology

One of the major causes of defective sperm function is oxidative stress, which not only disrupts the integrity of sperm DNA but also limits the fertilizing potential of these cells as a result of collateral damage to proteins and lipids in the sperm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b345bba623359916d1fdc84865cb86
http://www.ajandrology.com/article.asp?issn=1008-682X