Zobrazeno 1 - 10
of 190
pro vyhledávání: '"S, Jeruss"'
Autor:
Ravi M. Raghani Ph.D., Russell R. Urie Ph.D., Jeffrey A. Ma, Guillermo Escalona, Ian A. Schrack, Katarina M. DiLillo, Pridvi Kandagatla M.D., Joseph T. Decker Ph.D., Aaron H. Morris Ph.D., Kelly B. Arnold Ph.D., Jacqueline S. Jeruss M.D., Ph.D., Lonnie D. Shea Ph.D.
Publikováno v:
ImmunoMedicine, Vol 4, Iss 1, Pp n/a-n/a (2024)
Abstract Antibodies to programmed cell death protein 1 (anti‐PD‐1) have become a promising immunotherapy for triple negative breast cancer (TNBC), blocking PD‐L1 signaling from pro‐tumor cells through T cell PD‐1 receptor binding. Neverthel
Externí odkaz:
https://doaj.org/article/ade354aec4774e21aec8440151b31a5f
Autor:
Jing Wang, Ramon Ocadiz-Ruiz, Matthew S. Hall, Grace G. Bushnell, Sophia M. Orbach, Joseph T. Decker, Ravi M. Raghani, Yining Zhang, Aaron H. Morris, Jacqueline S. Jeruss, Lonnie D. Shea
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Biomaterial scaffolds mimicking the environment in metastatic organs can deconstruct complex signals and facilitate the study of cancer progression and metastasis. Here we report that a subcutaneous scaffold implant in mouse models of metast
Externí odkaz:
https://doaj.org/article/7ceec19b147f4e66ae168caae2f3b2a2
Autor:
Sophia M. Orbach, Christian Y. DeVaull, Elizabeth J. Bealer, Brian C. Ross, Jacqueline S. Jeruss, Lonnie D. Shea
Publikováno v:
Bioengineering & Translational Medicine, Vol 9, Iss 1, Pp n/a-n/a (2024)
Abstract Metastatic breast cancer is often not diagnosed until secondary tumors have become macroscopically visible and millions of tumor cells have invaded distant tissues. Yet, metastasis is initiated by a cascade of events leading to formation of
Externí odkaz:
https://doaj.org/article/998da597997e490e90000c9639339a9c
Myeloid cell reprogramming alleviates immunosuppression and promotes clearance of metastatic lesions
Autor:
Ravi M. Raghani, Jeffrey A. Ma, Yining Zhang, Sophia M. Orbach, Jing Wang, Mina Zeinali, Sunitha Nagrath, Sandeep Kakade, Qichen Xu, Joseph R. Podojil, Tushar Murthy, Adam Elhofy, Jacqueline S. Jeruss, Lonnie D. Shea
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Suppressive myeloid cells, including monocyte and neutrophil populations, play a vital role in the metastatic cascade and can inhibit the anti-tumor function of cytotoxic T-cells. Cargo-free polymeric nanoparticles (NPs) have been shown to modulate i
Externí odkaz:
https://doaj.org/article/bbd23894292c4b84ad0eca87089a47a9
Autor:
Jessica L. Thompson, Brandy R. Sinco, Rachel L. McCaffrey, Alfred E. Chang, Michael S. Sabel, Lesly A. Dossett, Tasha M. Hughes, Jacqueline S. Jeruss
Publikováno v:
Journal of Surgical Oncology. 127:18-27
Sentinel node biopsy (SLNB) is not routinely recommended for patients undergoing prophylactic mastectomy (PM), yet omission remains a subject of debate among surgeons. A modern patient cohort was examined to determine occult malignancy (OM) incidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19aed4057ebd120a5acc265ddc31bf93
https://doi.org/10.1002/jso.27088
https://doi.org/10.1002/jso.27088
Autor:
Sophia M. Orbach, Michael D. Brooks, Yining Zhang, Scott E. Campit, Grace G. Bushnell, Joseph T. Decker, Ryan J. Rebernick, Sriram Chandrasekaran, Max S. Wicha, Jacqueline S. Jeruss, Lonnie D. Shea
Publikováno v:
Clin Exp Metastasis
Microenvironmental changes in the early metastatic niche may be exploited to identify therapeutic targets to inhibit secondary tumor formation and improve disease outcomes. We dissected the developing lung metastatic niche in a model of metastatic, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbd6cb7cfcac5426109cddda6be2c72
https://doi.org/10.1007/s10585-022-10185-4
https://doi.org/10.1007/s10585-022-10185-4
Autor:
Taylor Novice, Madison Novice, David Portney, Joshua Goyert, N. Lynn Henry, Jacqueline S. Jeruss, Monika L. Burness
Publikováno v:
Supportive Care in Cancer. 30:8349-8355
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c7f3d214121013cd722b0a8bbcb72fa
https://doi.org/10.1007/s00520-022-07285-y
https://doi.org/10.1007/s00520-022-07285-y
Autor:
Sophia Orbach, Michael D. Brooks, Grace G. Bushnell, Max S. Wicha, Jacqueline S. Jeruss, Lonnie D. Shea
Publikováno v:
Journal of Clinical and Translational Science, Vol 4, Pp 5-6 (2020)
OBJECTIVES/GOALS: Breast cancer metastases are stochastic and difficult to detect. Therapy is often ineffective due to phenotypic changes of tumor cells at these sites. We engineered a synthetic metastatic niche to study the role of phenotypic transi
Externí odkaz:
https://doaj.org/article/c6dfa113ff9e49869012604e79527314
Autor:
Jessica L. Thompson, Steven G. Allen, Cecilia Pesavento, Corey W. Speers, Jacqueline S. Jeruss
Publikováno v:
Current Breast Cancer Reports. 14:75-82
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c53c4ae164fd6de94d30b736aec21576
https://doi.org/10.1007/s12609-022-00449-z
https://doi.org/10.1007/s12609-022-00449-z
Autor:
Rachel L McCaffrey, Jessica L Thompson, Rebecca H Oudsema, Andrew P Sciallis, Erin F Cobain, Michael S Sabel, Jacqueline S Jeruss
Publikováno v:
Journal of Surgical Oncology. 125:1218-1223
Given the significant benefit of targeted therapies for HER2+ breast cancer patients in both the neoadjuvant and adjuvant settings, it is critical to identify all eligible patients for these treatments. We sought to investigate cT1cN0 HER2+ patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7860f037be6270cd82f6ef6ab319f2b9
https://doi.org/10.1002/jso.26840
https://doi.org/10.1002/jso.26840