Zobrazeno 1 - 10
of 228
pro vyhledávání: '"S, Jaken"'
Autor:
S, Jaken, P J, Parker
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 22(3)
Members of the protein kinase C family respond to second messengers and are involved in controlling a broad array of cellular functions. The overlapping specificity and promiscuity of these proteins has promoted the view that specific binding protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ef2b2a4cc5c66d9736259570257b4a7
https://pubmed.ncbi.nlm.nih.gov/10684584
https://pubmed.ncbi.nlm.nih.gov/10684584
Autor:
Ricardo C. Moraes, Raghu Sinha, S.C Kiley, Daniel Medina, Junxuan Lu, Henry J. Thompson, S Jaken
Publikováno v:
Cancer letters. 146(2)
Methylselenocysteine (MSC), an organic selenium compound is an effective chemopreventive agent against mammary cell growth both in vivo and in vitro but its mechanism of action is still not understood. We have previously demonstrated that MSC is able
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e133d7a3ca5001cd4abf5c6df95688b3
https://pubmed.ncbi.nlm.nih.gov/10656618
https://pubmed.ncbi.nlm.nih.gov/10656618
Publikováno v:
Cancer research. 59(13)
Metastasis requires cytoskeletal remodeling for migration, adhesion, and extravasation of metastatic cells. Although protein kinase C (PKC) is involved in tumor promotion/progression and cytoskeletal remodeling, its role in metastasis has not been de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::668f211288c112f35a30cb1c3de8e6ef
https://pubmed.ncbi.nlm.nih.gov/10397270
https://pubmed.ncbi.nlm.nih.gov/10397270
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 9(2)
Adducins are cytoskeletal proteins that facilitate interactions between spectrin and actin to form the subcortical membrane skeleton. We recently determined that alpha- and gamma-adducins are among a group of PKC substrates that we have designated "S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::669d86fa614240d970fa08f3801866cd
https://pubmed.ncbi.nlm.nih.gov/9486854
https://pubmed.ncbi.nlm.nih.gov/9486854
Publikováno v:
The Journal of biological chemistry. 271(11)
We have used an interaction cloning strategy to isolate cDNAs for sequences that interact with protein kinase C (Chapline, C., Ramsay, K., Klauck, T., and Jaken, S. (1993) J. Biol. Chem. 268,6858-6861). In this paper, we report a novel sequence, clon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a107668a401f02408671cd8fb8271b06
https://pubmed.ncbi.nlm.nih.gov/8626441
https://pubmed.ncbi.nlm.nih.gov/8626441
Publikováno v:
The Journal of biological chemistry. 270(1)
We have previously reported that two closely related protein kinase C (PKC) isoforms, PKC alpha and PKC beta I, had divergent effects on the growth and transformation of the same parental R6 rat embryo fibroblast cell line (Housey, G. M., Johnson, M.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9725578157562c2369a3ac3275991181
https://pubmed.ncbi.nlm.nih.gov/7814423
https://pubmed.ncbi.nlm.nih.gov/7814423
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 5(11)
The role of individual protein kinase C (PKC) isoforms in progressive transformation of a rat embryo fibroblast cell line (REF52 cells) has been evaluated. Normal (REF A) cells were transfected with SV40 to produce the partially transformed REF B cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f47e00d47a5e39fa66266752130038e6
https://pubmed.ncbi.nlm.nih.gov/7848920
https://pubmed.ncbi.nlm.nih.gov/7848920
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 5(8)
Renal alpha-protein kinase C (PKC) is rapidly down-modulated modulated in animals treated with the renal toxin and tumor promoter, folic acid (Dong et al., Cancer Res., 53: 4542-4549, 1993). To further explore the role of PKC isozymes in renal growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45dbffabd3ac2f9f6057f77b363cc25d
https://pubmed.ncbi.nlm.nih.gov/7986753
https://pubmed.ncbi.nlm.nih.gov/7986753
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 5(3)
Treatment of HC11 mouse mammary epithelial cells with the lactogenic hormones dexamethasone, insulin, and prolactin (DIP) leads to cellular differentiation and production of the milk protein beta-casein. The following experimental evidence suggests t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d07db706815814b8dd76dc33174edd6
https://pubmed.ncbi.nlm.nih.gov/8018556
https://pubmed.ncbi.nlm.nih.gov/8018556
Publikováno v:
Cancer research. 53(19)
Tissue damage and repair processes are important factors in renal tumor progression. To determine whether protein kinase C (PKC) is involved in these processes, we characterized PKC isozymes during rat kidney regeneration using 3 models: (a) diffuse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::01f33bf031f06d744d3a3d51375165e1
https://pubmed.ncbi.nlm.nih.gov/8402625
https://pubmed.ncbi.nlm.nih.gov/8402625