Cryptococcus neoformans Glucuronoxylomannan and Sterylglucoside Are Required for Host Protection in an Animal Vaccination Model

Autor: Ana Caroline Colombo, Antonella Rella, Tyler Normile, Luna S. Joffe, Patricia M. Tavares, Glauber R. de S. Araújo, Susana Frases, Erika P. Orner, Amir M. Farnoud, Bettina C. Fries, Brian Sheridan, Leonardo Nimrichter, Marcio L. Rodrigues, Maurizio Del Poeta

Publikováno v: mBio, Vol 10, Iss 2 (2019)

ABSTRACT Cryptococcus neoformans is an encapsulated fungal pathogen that causes meningoencephalitis. There are no prophylactic tools for cryptococcosis. Previously, our group showed that a C. neoformans mutant lacking the gene encoding sterylglucosid

Externí odkaz: https://doaj.org/article/52d022ef29b64652848b6962dc1e3a60

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Biogenesis of extracellular vesicles in yeast Many questions with few answers

Autor: Débora L. Oliveira, Ernesto S. Nakayasu, Luna S. Joffe, Allan J. Guimarães, Tiago J. P. Sobreira, Joshua D. Nosanchuk, Radames J. B. Cordero, Susana Frases, Arturo Casadevall, Igor C. Almeida, Leonardo Nimrichter, Marcio L. Rodrigues

Publikováno v: Communicative & Integrative Biology, Vol 3, Iss 6, Pp 533-535 (2010)

The cellular events required for unconventional protein secretion in eukaryotic pathogens are beginning to be revealed. In fungi, extracellular release of proteins involves passage through the cell wall by mechanisms that are poorly understood. In re

Externí odkaz: https://doaj.org/article/f70777939adb43429621931b9957f66d

Dental side effects of long-term obstructive sleep apnea therapy: a 10-year follow-up study

Autor: Boudewijn Stegenga, Dilyana S Joffe-Sokolova, Peter J. Wijkstra, Aarnoud Hoekema, Julia A. M. Uniken Venema, Johannes H. van der Hoeven, Michiel H. J. Doff

Publikováno v: Clinical Oral Investigations, 24. SPRINGER HEIDELBERG
Clinical Oral Investigations, 24(9), 3069-3076. Springer Verlag
Uniken Venema, J A M, Doff, M H J, Joffe-Sokolova, D S, Wijkstra, P J, van der Hoeven, J H, Stegenga, B & Hoekema, A 2020, ' Dental side effects of long-term obstructive sleep apnea therapy : a 10-year follow-up study ', Clinical Oral Investigations, vol. 24, no. 9, pp. 3069-3076 . https://doi.org/10.1007/s00784-019-03175-6

OBJECTIVES: Patients with obstructive sleep apnea (OSA) are usually treated with either mandibular advancement device (MAD) or continuous positive airway pressure (CPAP) therapy. The objective of this study is to evaluate changes in dental occlusion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0c41ca766ded52a962cefd00edc54f
https://research.rug.nl/en/publications/225abce8-266c-4fb5-8d6d-b773e55812b4

Hypervirulence and cross-resistance to a clinical antifungal are induced by an environmental fungicide in Cryptococcus gattii

Autor: Dee A. Carter, Noelly Queiroz Ribeiro, Jônatas Santos Abrahão, Tatiane A. Paixão, Marliete Carvalho Costa, Daniel Assis Santos, Glauber R. de S. Araújo, Thais Furtado Ferreira Magalhães, Jeronimo C. Ruiz, Paula Eillany Silva Marinho, Rafael Wesley Bastos, Susana Frases, Marcio L. Rodrigues, Hellem Cristina Silva Carneiro, Ludmila Gouveia-Eufrasio, Lorena Vívien Neves de Oliveira, Luna S. Joffe, Maria Aparecida Resende-Stoianoff

Publikováno v: The Science of the total environment. 740

The increasing human population requires ongoing efforts in food production. This is frequently associated with an increased use of agrochemicals, leading to environmental contamination and altering microbial communities, including human fungal patho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f608e3b2535d73f93373f13b682f369
https://pubmed.ncbi.nlm.nih.gov/32927573