Zobrazeno 1 - 10
of 169
pro vyhledávání: '"S, Ingham"'
Autor:
Brett Z. Fite, James Wang, Aris J. Kare, Asaf Ilovitsh, Michael Chavez, Tali Ilovitsh, Nisi Zhang, Weiyu Chen, Elise Robinson, Hua Zhang, Azadeh Kheirolomoom, Matthew T. Silvestrini, Elizabeth S. Ingham, Lisa M. Mahakian, Sarah M. Tam, Ryan R. Davis, Clifford G. Tepper, Alexander D. Borowsky, Katherine W. Ferrara
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract High intensity focused ultrasound (HIFU) rapidly and non-invasively destroys tumor tissue. Here, we sought to assess the immunomodulatory effects of MR-guided HIFU and its combination with the innate immune agonist CpG and checkpoint inhibit
Externí odkaz:
https://doaj.org/article/3b05fd16d36d4a2eaa4db739670dbc41
Autor:
Jai Woong Seo, Elizabeth S. Ingham, Lisa Mahakian, Spencer Tumbale, Bo Wu, Sadaf Aghevlian, Shahin Shams, Mo Baikoghli, Poorva Jain, Xiaozhe Ding, Nick Goeden, Tatyana Dobreva, Nicholas C. Flytzanis, Michael Chavez, Kratika Singhal, Ryan Leib, Michelle L. James, David J. Segal, R. Holland Cheng, Eduardo A. Silva, Viviana Gradinaru, Katherine W. Ferrara
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Adeno-associated viruses (AAVs) can be targeted in a tissue-specific manner, but their tissue accumulation cannot be assessed in a non-invasive manner. Here the authors conjugate a multivalent chelator labelled with Cu-64 to the surface of AAVs and i
Externí odkaz:
https://doaj.org/article/3bffb0cc262e4293b560a67f7e3c6fd9
Autor:
Terje Sundstrøm, Lars Prestegarden, Francisco Azuaje, Synnøve Nymark Aasen, Gro Vatne Røsland, Jobin K. Varughese, Marzieh Bahador, Simon Bernatz, Yannick Braun, Patrick N. Harter, Kai Ove Skaftnesmo, Elizabeth S. Ingham, Lisa M. Mahakian, Sarah Tam, Clifford G. Tepper, Kjell Petersen, Katherine W. Ferrara, Karl Johan Tronstad, Morten Lund-Johansen, Rudi Beschorner, Rolf Bjerkvig, Frits Thorsen
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-19 (2019)
Abstract Melanoma patients carry a high risk of developing brain metastases, and improvements in survival are still measured in weeks or months. Durable disease control within the brain is impeded by poor drug penetration across the blood-brain barri
Externí odkaz:
https://doaj.org/article/a1c9daff0c9545dea71bc7623876a310
Autor:
Katherine W. Ferrara, Anna M. Wu, Alexander D. Borowsky, Felix B. Salazar, Elizabeth S. Ingham, Sarah Tam, Matthew T. Silvestrini, Lisa M. Mahakian, Richard Tavaré, Jai Woong Seo
Purpose: Noninvasive and quantitative tracking of CD8+ T cells by PET has emerged as a potential technique to gauge response to immunotherapy. We apply an anti-CD8 cys-diabody, labeled with 64Cu, to assess the sensitivity of PET imaging of normal and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ce534925736e27057805a5dfcd2bfd
https://doi.org/10.1158/1078-0432.c.6529188.v1
https://doi.org/10.1158/1078-0432.c.6529188.v1
Autor:
Katherine W. Ferrara, Anna M. Wu, Alexander D. Borowsky, Felix B. Salazar, Elizabeth S. Ingham, Sarah Tam, Matthew T. Silvestrini, Lisa M. Mahakian, Richard Tavaré, Jai Woong Seo
Supplementary Figures and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00514919634ec8bdc6b9eeef05f53699
https://doi.org/10.1158/1078-0432.22475835.v1
https://doi.org/10.1158/1078-0432.22475835.v1
Autor:
Katherine W. Ferrara, Rolf K. Reed, Fitz-Roy Curry, Elizabeth S. Ingham, Julie Beegle, Lisa M. Mahakian, Robert D. Cardiff, Jai Woong Seo, Yueh-Chen Lin, Dustin E. Kruse, Shengping Qin, Chun-Yen Lai, Katherine D. Watson
PDF file - 137K, Detailed relationship between the PAP parameter derived through the image-guided model with the classical parameters of solute transport coefficient, clearance, and 30 minute albumin clearance (Cl30).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa726c16dad20ce65a4f8070483de88f
https://doi.org/10.1158/0008-5472.22395672.v1
https://doi.org/10.1158/0008-5472.22395672.v1
Autor:
Katherine W. Ferrara, Rolf K. Reed, Fitz-Roy Curry, Elizabeth S. Ingham, Julie Beegle, Lisa M. Mahakian, Robert D. Cardiff, Jai Woong Seo, Yueh-Chen Lin, Dustin E. Kruse, Shengping Qin, Chun-Yen Lai, Katherine D. Watson
PDF file - 51K, Representative biodistribution of tissues 48 hours after nanoparticle injection (N=8). Accumulation was significantly greater for insonified tumors (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8915b300c46299932ec58bda66c4339d
https://doi.org/10.1158/0008-5472.22395675.v1
https://doi.org/10.1158/0008-5472.22395675.v1
Autor:
Spencer K. Tumbale, R. Holland Cheng, Elizabeth S. Ingham, Wei-Lun Tang, Sarah M. Tam, Bo Wu, Alexander D. Borowsky, Katherine W. Ferrara, Mo Baikoghli, Marina Nura Raie, Brett Z. Fite, Josquin Foiret, Azadeh Kheirolomoom, Lisa M. Mahakian, Hua Zhang, Kenneth Lau
Publikováno v:
J Control Release
Resiquimod (R848) is a toll-like receptor 7 and 8 (TLR7/8) agonist with potent antitumor and immunostimulatory activity. However, systemic delivery of R848 is poorly tolerated because of its poor solubility in water and systemic immune activation. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b9f8e20c827e35ad60b79d473d2225
https://doi.org/10.1016/j.jconrel.2020.11.013
https://doi.org/10.1016/j.jconrel.2020.11.013
Autor:
Poorva Jain, Eduardo A. Silva, Spencer K. Tumbale, Michelle L. James, Ryan D. Leib, Katherine W. Ferrara, Mo Baikoghli, Jai Woong Seo, Tatyana Dobreva, Michael Chavez, Bo Wu, David J. Segal, Nick Goeden, R. Holland Cheng, Lisa M. Mahakian, Kratika Singhal, Nicholas C. Flytzanis, Shahin Shams, Xiaozhe Ding, Elizabeth S. Ingham, Sadaf Aghevlian, Viviana Gradinaru
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature communications, vol 11, iss 1
Nature Communications
Nature communications, vol 11, iss 1
Nature Communications
Adeno-associated viruses (AAVs) are typically single-stranded deoxyribonucleic acid (ssDNA) encapsulated within 25-nm protein capsids. Recently, tissue-specific AAV capsids (e.g. PHP.eB) have been shown to enhance brain delivery in rodents via the LY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42ccb8a9da961505b625249c18388a8
https://doaj.org/article/3bffb0cc262e4293b560a67f7e3c6fd9
https://doaj.org/article/3bffb0cc262e4293b560a67f7e3c6fd9
Publikováno v:
Australian Journal of Structural Engineering. 20:204-218
Net wind pressures acting across solar panels were obtained by testing 1/20 scale models in a range of typical array configurations in the wind tunnel. This paper presents data for a typical panel array configuration inclined at α = 20°. Large net
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f87e3763a6a5e4f5e30053c11270b57c
https://doi.org/10.1080/13287982.2019.1623001
https://doi.org/10.1080/13287982.2019.1623001