Zobrazeno 1 - 10
of 32 399
pro vyhledávání: '"S, Hong"'
Autor:
Joseph D. Butner, Prashant Dogra, Caroline Chung, Eugene J. Koay, James W. Welsh, David S. Hong, Vittorio Cristini, Zhihui Wang
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract We present a study where predictive mechanistic modeling is combined with deep learning methods to predict individual patient survival probabilities under immune checkpoint inhibitor (ICI) immunotherapy. This hybrid approach enables predicti
Externí odkaz:
https://doaj.org/article/ec3e14cd43a442aab424aba4348ea914
Autor:
Nikhil Bharti, Leonardo Santos, Marcos Davyt, Stine Behrmann, Marie Eichholtz, Alejandro Jimenez-Sanchez, Jeong S. Hong, Andras Rab, Eric J. Sorscher, Suki Albers, Zoya Ignatova
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Nonsense mutations – the underlying cause of approximately 11% of all genetic diseases – prematurely terminate protein synthesis by mutating a sense codon to a premature stop or termination codon (PTC). An emerging therapeutic strategy t
Externí odkaz:
https://doaj.org/article/7320e409d0a640aa9c9dacd192b22128
Autor:
Bishoy N. Saad, DO, Luke G. Menken, DO, David M. Keller, DO, Yajesh Rampertaap, DO, Alex Tang, MD, Ian S. Hong, MD, Frank A. Liporace, MD, Richard S. Yoon, MD, Jaclyn M. Jankowski, DO
Publikováno v:
OTA International, Vol 7, Iss 3 (2024)
Abstract. Introduction:. Delay to surgery >24 hours has been shown to correlate with mortality rates in patients with hip fracture when left untreated. Many of these patients have multiple comorbidities, including aortic stenosis (AS), and undergo wo
Externí odkaz:
https://doaj.org/article/438a36336efe4a1080e51089e80d920a
Autor:
Heather Lin, Vivek Subbiah, Siqing Fu, Aung Naing, Courtney Nicholas, Shubham Pant, Chad Tang, Michael A Curran, David S Hong, Ying Yuan, Sarina A Piha-Paul, Jordi Rodon Ahnert, Timonthy A Yap, Apostolia M Tsimberidou, Daniel D Karp, Anupallavi Srinivasamani, Coline Couillault, Genevieve P Hartley, James Dai, Ecaterina E Ileana Dumbrava, Paola Guerrero, Sarah Dhebat, Theresa Proia
Publikováno v:
BMJ Oncology, Vol 3, Iss 1 (2024)
Objective To evaluate signal transducer and activator of transcription 3 (STAT3) inhibition we conducted a co-clinical trial testing danvatirsen, a STAT3 antisense oligonucleotide (ASO) and checkpoint inhibition in conjunction with preclinical experi
Externí odkaz:
https://doaj.org/article/fd1c2105b438497dab4139b2a44f11d7
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
The clinical research pipeline is critical to ensuring continued development of novel treatments that can offer patients with cancer safe and effective options. Unfortunately, progress has slowed since the COVID-19 pandemic due to uncovered, systemic
Externí odkaz:
https://doaj.org/article/411006a42ab147bf8691be7123885805
Autor:
Manoop S. Bhutani, Amol K. Narang, Kai Ding, Brenna Casey, Kumar Krishnan, Eugene J. Koay, Theodore S. Hong, Joseph M. Herman, Kristen H. Griffin, Eun Ji Shin
Publikováno v:
Endoscopy International Open, Vol 12, Iss 07, Pp E861-E867 (2024)
Externí odkaz:
https://doaj.org/article/9ca876c7bb074d1390882e487ee42e97
Autor:
Savanna L. Carson, Francesca Cameron, Diamond Lee, Diana Zúñiga, Kelli Poole, Adjoa Jones, Cristina Herman, Mayra Ramirez, Simone Harlow, Jeannette Johnson, Etsemaye P. Agonafer, Clemens S. Hong, Arleen F. Brown
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background To facilitate safety-net healthcare system partnerships with community social service providers, the Los Angeles County Department of Health Services (LAC DHS) created a new collaboration team to spur cross-agency social and medic
Externí odkaz:
https://doaj.org/article/81bb3e76154a4abea5785a75f522f52e
Autor:
Kathryn E. Hitchcock, Eric D. Miller, Qian Shi, Jesse G. Dixon, Sepideh Gholami, Sarah B. White, Christina Wu, Christopher C. Goulet, Manju George, Kyung-Wook Jee, Chadwick L. Wright, Rona Yaeger, Ardaman Shergill, Theodore S. Hong, Thomas J. George, Eileen M. O’Reilly, Jeffrey A. Meyerhardt, Paul B. Romesser
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background For patients with liver-confined metastatic colorectal cancer (mCRC), local therapy of isolated metastases has been associated with long-term progression-free and overall survival (OS). However, for patients with more advanced mCR
Externí odkaz:
https://doaj.org/article/a12441bd0abc4f59b450ff5143ff3561
Autor:
Kwansuk Oh, Yoo S. Hong
Publikováno v:
IEEE Access, Vol 12, Pp 108810-108824 (2024)
Product variety has a complex impact on both market share and complexity cost, so determining an optimal variety is a difficult task for a manufacturing company. This paper proposes a variety optimization model that reflects the relationships among m
Externí odkaz:
https://doaj.org/article/bc96e9fbb0da4f33a9c251f1ddeb18b8
Autor:
Chia-Chi Lin, Elena Garralda, Patrick Schöffski, David S. Hong, Lillian L. Siu, Miguel Martin, Michela Maur, Rina Hui, Ross A Soo, Joanne Chiu, Tian Zhang, Brigette Ma, Chrisann Kyi, Daniel SW Tan, Philippe A. Cassier, John Sarantopoulos, Andrew Weickhardt, Richard D. Carvajal, Jennifer Spratlin, Taito Esaki, Fréderic Rolland, Wallace Akerley, Barbara Deschler-Baier, Lawrence Rispoli, Tanay S. Samant, Niladri Roy Chowdhury, Daniel Gusenleitner, Eunice L. Kwak, Vasileios Askoxylakis, Filippo De Braud
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTIeramilimab, a humanized anti-LAG-3 monoclonal antibody, was well tolerated in combination with the anti-PD-1 antibody spartalizumab in a phase 1 study. This phase 2 study aimed to further investigate the efficacy and safety of combination tr
Externí odkaz:
https://doaj.org/article/fba32163599d40e7abcb0008f2589a1a