IFN-gamma and CD8+ T cells restore host defenses against Pneumocystis carinii in mice depleted of CD4+ T cells

Autor: J K, Kolls, S, Habetz, M K, Shean, C, Vazquez, J A, Brown, D, Lei, P, Schwarzenberger, P, Ye, S, Nelson, W R, Summer, J E, Shellito

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 162(5)

Host defenses against infection are profoundly compromised in HIV-infected hosts due to progressive depletion of CD4+ T lymphocytes and defective cell-mediated immunity. Although recent advances in antiretroviral therapy can dramatically lower HIV vi

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https://pubmed.ncbi.nlm.nih.gov/10072538

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IFN-gamma and CD8+ T cells restore host defenses against Pneumocystis carinii in mice depleted of CD4+ T cells.

Autor: Kolls JK; Section of Pulmonary/Critical Care, Gene Therapy Program, and Section of Hematology/Oncology, Louisiana State University Medical Center School of Medicine, New Orleans, LA 70112, USA. jkolls@lsumc.edu, Habetz S, Shean MK, Vazquez C, Brown JA, Lei D, Schwarzenberger P, Ye P, Nelson S, Summer WR, Shellito JE

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 1999 Mar 01; Vol. 162 (5), pp. 2890-4.