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pro vyhledávání: '"S, Gralewicz"'
Autor:
S, Gralewicz, D, Wiaderna
Publikováno v:
Neurotoxicology. 22(1)
Trimethylbenzene (TMB), like xylene (dimethylbenzene), is a significant constituent of some industrial solvent mixtures. In earlier studies, we found that in the rat a subacute low-level inhalation exposure to some of the TMB isomers may result in be
Publikováno v:
International journal of occupational medicine and environmental health. 13(3)
We investigated the effect of acute exposure to chlorphenvinphos (CVP) (2-chloro-1 (2,4-dichlorophenyl)-vinyl-diethyl-phosphate), an organophosphate anticholinesterase, on the amphetamine- and scopolamine-induced open-field locomotion in Wistar rats.
Publikováno v:
Acta neurobiologiae experimentalis. 60(3)
A certain proportion of laboratory rats of various strains show spontaneous nonconvulsive ECoG seizures in the form of bursts of spike-and-wave discharges (SWD). Since in the majority of behavioural experiments the EEG is not controlled, the experime
Publikováno v:
Acta neurobiologiae experimentalis. 60(2)
We investigated the effect of an acute exposure to chlorphenvinphos (CVP), an organophosphate anticholinesterase, on amphetamine-induced open-field locomotion in rats. CVP was administered in a single i.p. dose of 1.0 mg/kg (1/10 of the LD50). All an
Autor:
S, Gralewicz
Publikováno v:
International journal of occupational medicine and environmental health. 12(4)
The nervous system is main target of the toxic action of most of organic solvents. There is little doubt that occupational solvent exposure may result in persisting neurobehavioural disturbances--the organic solvent syndrome. Recently, the solvents a
Publikováno v:
International journal of occupational medicine and environmental health. 12(4)
This study was performed to find out whether in acute exposure to trimethylbenzene (TMB) isomers the dose effect relationship is linear or biphasic. In experiments performed on rats, the effect of four solvents was studied: three TMB isomers: 1,3,5-T
Autor:
S, Gralewicz
Publikováno v:
International journal of occupational medicine and environmental health. 12(3)
A proportion of subjects of rat strains and lines commonly used for behavioural research in neurotoxicology, neuropharmacology and related fields show spontaneous generalized nonconvulsive EEG seizures. The seizures have the form of bursts of spike a
Publikováno v:
International journal of occupational medicine and environmental health. 12(2)
The aim of the present study was to investigate persistent neurobehavioural effects of repeated low-level exposure to chlorphenvinphos ((2-chloro-1-(2,4-dichlorophenyl) vinyl diethyl phosphate-CVP) in rats. The rats received 10 i.p. injections of CVP
Publikováno v:
International journal of occupational medicine and environmental health. 11(4)
Trimethylbenzene isomers (TMBs): 1,2,4-TMB (pseudocumene--PS), 1,2,3-TMB (hemimellitene--HM) and 1,3,5-TMB (mesitylene--MES) are important constituents of solvent mixtures. In the US, the adopted TLV-TWA value for TMBs is 125 mg/m3 or 25 ppm (ACGIH 1
Autor:
S, Gralewicz
Publikováno v:
Medycyna pracy. 49(5)
Multiplechemical sensitivity (MCS) is a chronic condition manifested by the appearance of variable symptoms, involving many systems and organs, after exposure to extremely low levels of chemicals, mainly pesticides and solvents. The paper discusses b