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Lactobacilli intra-tracheal administration protects from Pseudomonas aeruginosa pulmonary infection in mice – a proof of concept

Autor: S. Gouriou, M.-S. Fangous, D Arzur, Youenn Alexandre, Nolwenn Hymery, G Le Blay, R. Le Berre

Publikováno v: Beneficial Microbes
Beneficial Microbes, Wageningen Academic Publishers 2019, 10 (8), pp.893-900. ⟨10.3920/BM2019.0069⟩

WOS:000501544400007; International audience; The spreading of antibiotic resistance is a major public health issue, which requires alternative treatments to antibiotics. Lactobacilli have shown abilities to prevent pneumonia in clinical studies when

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc060ababe1051648187c04b338f4a6
https://doi.org/10.3920/bm2019.0069

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Priming with intranasal lactobacilli prevents Pseudomonas aeruginosa acute pneumonia in mice

Autor: Philippe Gosset, Christopher Payan, Charles-Antoine Guilloux, M.-S. Fangous, Rozenn Le Berre, S. Vallet, S. Gouriou, Nicolas Galakhoff, Geneviève Héry-Arnaud

Publikováno v: BMC Microbiology
BMC Microbiology, BioMed Central, 2021, 21 (1), pp.195. ⟨10.1186/s12866-021-02254-7⟩
BMC Microbiology, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Microbiology, 2021, 21 (1), pp.195. ⟨10.1186/s12866-021-02254-7⟩

Background : Increasing resistance to antibiotics of Pseudomonas aeruginosa leads to therapeutic deadlock and alternative therapies are needed. We aimed to evaluate the effects of Lactobacillus clinical isolates in vivo, through intranasal administra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c77df13fd7f82272163e9b3cce1ff51e
https://doi.org/10.1186/s12866-021-02254-7

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Prevotella melaninogenica, a Sentinel Species of Antibiotic Resistance in Cystic Fibrosis Respiratory Niche?

Autor: Geneviève Héry-Arnaud, Elise Courteboeuf, S. Gouriou, Charles-Antoine Guilloux, Claudie Lamoureux, Clémence Beauruelle

Publikováno v: Microorganisms
Volume 9
Issue 6
Microorganisms, MDPI, 2021, 9 (6), pp.1275. ⟨10.3390/microorganisms9061275⟩
Microorganisms, Vol 9, Iss 1275, p 1275 (2021)

International audience; The importance and abundance of strict anaerobic bacteria in the respiratory microbiota of people with cystic fibrosis (PWCF) is now established through studies based on high-throughput sequencing or extended-culture methods.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e87176464f272b3cb977acd0308ed2f
http://europepmc.org/articles/PMC8230849

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Lactobacilli intra-tracheal administration protects from

Autor: M S, Fangous, Y, Alexandre, N, Hymery, S, Gouriou, D, Arzur, G Le, Blay, R Le, Berre

Publikováno v: Beneficial microbes. 10(8)

The spreading of antibiotic resistance is a major public health issue, which requires alternative treatments to antibiotics. Lactobacilli have shown abilities to prevent pneumonia in clinical studies when given by oral route, certainly through the gu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aa63d39a205ccc342c732e311f871758
https://pubmed.ncbi.nlm.nih.gov/31965833

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Prevalence and dynamics of Lactobacillus sp. in the lower respiratory tract of patients with cystic fibrosis

Autor: Youenn Alexandre, Ismaïl Lazzouni, Marie-Sarah Fangous, S. Gouriou, Jean Le Bihan, Rozenn Le Berre, Sylvie Boisramé, Sophie Vallet, S. Ramel, Geneviève Héry-Arnaud

Publikováno v: Research in Microbiology. 169:222-226

No prevalence or dynamics analysis of Lactobacilli in the lung of cystic fibrosis (CF) patients has yet been conducted. In order to use them as probiotics in the treatment of Pseudomonas aeruginosa infection, we describe their lung epidemiology. Over

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420ecb626c84471b19df18ed03c77756
https://doi.org/10.1016/j.resmic.2018.03.005

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Intranasal or oral Lactobacilli administration: Which one is best for fighting against Pseudomonas aeruginosa (PA) respiratory tract infections?

Autor: Geneviève Héry-Arnaud, Charles-Antoine Guilloux, P. Gosset, S. Gouriou, S. Vallet, M.-S. Fangous, R. Lagrafeuille, R. Le Berre

Publikováno v: Revue des Maladies Respiratoires. 38:583

Introduction In CF patients, PA chronic lung infections combined with acquisition of antibiotics resistance leads to therapeutic deadlock. Among non-antibiotic alternative, the use of Lactobacilli is promising since its oral administration (OA) stimu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea0c7c1333257ec085955577c417b30e
https://doi.org/10.1016/j.rmr.2021.02.032

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Porphyromonas, a neglected potential key genus of the lung microbiota: description in patients with cystic fibrosis (CF)

Autor: Charles-Antoine Guilloux, S. Gouriou, Clémence Beauruelle, Claudie Lamoureux, Geneviève Héry-Arnaud

Publikováno v: Revue des Maladies Respiratoires. 38:586

Introduction Recent data showed the importance of anaerobes in chronic pulmonary diseases. To date, their impact on lung homeostasis is not clearly established and metagenomics studies provide a limited description of those key bacteria. We investiga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::736bb0d31738a58f96520afb6f58c11a
https://doi.org/10.1016/j.rmr.2021.02.038

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