Zobrazeno 1 - 10
of 676
pro vyhledávání: '"S, Gorantla"'
Autor:
Ashti M. Shah, Ali Mubin Aral, Ruben Zamora, Nitin Gharpure, Fayten El-Dehaibi, Fatih Zor, Yalcin Kulahci, Huseyin Karagoz, Derek A. Barclay, Jinling Yin, Warren Breidenbach, Dmitry Tuder, Vijay S. Gorantla, Yoram Vodovotz
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionVascularized composite allotransplantation (VCA), with nerve repair/coaptation (NR) and tacrolimus (TAC) immunosuppressive therapy, is used to repair devastating traumatic injuries but is often complicated by inflammation spanning multipl
Externí odkaz:
https://doaj.org/article/c1d1411875884cb2b63df6b80b7200c0
Autor:
Wensheng Zhang, Yong Wang, Fushun Zhong, Xinghuan Wang, Robert Sucher, Cheng-Hung Lin, Gerald Brandacher, Mario G. Solari, Vijay S. Gorantla, Xin Xiao Zheng
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Compelling experimental evidence confirms that the robustness and longevity of mixed chimerism (MC) relies on the persistence and availability of donor-derived hematopoietic stem cell (HSC) niches in recipients. Based on our prior work in rodent vasc
Externí odkaz:
https://doaj.org/article/8e41af8c010d4f2db7bb8bea0a628768
Autor:
Astgik Petrosyan, Paulo N. Martins, Kim Solez, Basak E. Uygun, Vijay S. Gorantla, Giuseppe Orlando
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Insights into the use of cellular therapeutics, extracellular vesicles (EVs), and tissue engineering strategies for regenerative medicine applications are continually emerging with a focus on personalized, patient-specific treatments. Multiple pre-cl
Externí odkaz:
https://doaj.org/article/eac323c029084f3c8588277a140aa33c
Autor:
Riddhi Vichare, Caitlin Crelli, Lu Liu, Amit Chandra Das, Rebecca McCallin, Fatih Zor, Yalcin Kulahci, Vijay S. Gorantla, Jelena M. Janjic
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2372 (2023)
Despite long-term immunosuppression, organ transplant recipients face the risk of immune rejection and graft loss. Tacrolimus (TAC, FK506, Prograf®) is an FDA-approved keystone immunosuppressant for preventing transplant rejection. However, it under
Externí odkaz:
https://doaj.org/article/2d8a2c15964e491395c5ac8a1a2fcf8f
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
The use of autografted nerve in surgical repair of peripheral nerve injuries (PNI) is severely limited due to donor site morbidity and restricted tissue availability. As an alternative, synthetic nerve guidance channels (NGCs) are available on the ma
Externí odkaz:
https://doaj.org/article/8ba85abc332240939ef676c895f7188c
Autor:
Ali Mubin Aral, Ruben Zamora, Derek Barclay, Jinling Yin, Fayten El-Dehaibi, Vasil E. Erbas, Liwei Dong, Zhaoxiang Zhang, Huseyin Sahin, Vijay S. Gorantla, Yoram Vodovotz
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Systems-level insights into inflammatory events after vascularized composite allotransplantation (VCA) are critical to the success of immunomodulatory strategies of these complex procedures. To date, the effects of tacrolimus (TAC) immunosuppression
Externí odkaz:
https://doaj.org/article/07aa1e49e1a945ebaa55d340213ab5f5
Autor:
Riccardo Schweizer, MD, Jonas T. Schnider, MD, Paolo M. Fanzio, MD, Wakako Tsuji, MD, PhD, Nataliya Kostereva, PhD, Mario G. Solari, MD, Jan A. Plock, MD, Vijay S. Gorantla, MD, PhD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 8, Iss 7, p e2953 (2020)
Background:. Regardless of etiology, peripheral nerve injuries (PNI) result in disruption/loss of neuromuscular junctions, target muscle denervation, and poor sensorimotor outcomes with associated pain and disability. Adipose-derived stem cells (ASCs
Externí odkaz:
https://doaj.org/article/72ade245c7554bc8bd34b3b7ecdfc420
Autor:
Riccardo Schweizer, Matthias Waldner, Sinan Oksuz, Wensheng Zhang, Chiaki Komatsu, Jan A. Plock, Vijay S. Gorantla, Mario G. Solari, Lauren Kokai, Kacey G. Marra, J. Peter Rubin
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Background: Mesenchymal stromal cell (MSC)-based cytotherapies fuel the hope for reduction of chronic systemic immunosuppression in allotransplantation, and our group has previously shown this capability for both swine and human cells. MSCs harvested
Externí odkaz:
https://doaj.org/article/85c83be9838945c1acd1a21f2586a926
Autor:
Yolandi van der Merwe, Anne E. Faust, Ian Conner, Xinzhu Gu, Firuz Feturi, Wenchen Zhao, Bianca Leonard, Souvik Roy, Vijay S. Gorantla, Raman Venkataramanan, Kia M. Washington, William R. Wagner, Michael B. Steketee
Publikováno v:
EBioMedicine, Vol 26, Iss C, Pp 47-59 (2017)
Central nervous system (CNS) neurons fail to regrow injured axons, often resulting in permanently lost neurologic function. Tacrolimus is an FDA-approved immunosuppressive drug with known neuroprotective and neuroregenerative properties in the CNS. H
Externí odkaz:
https://doaj.org/article/f9b3b4ab375b44bf83f205189b82cd93
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