Zobrazeno 1 - 10
of 131
pro vyhledávání: '"S, Ghatge"'
Autor:
Rana T. Alhashimi, Tarek A. Ahmed, Lamya Alghanem, Piyusha P. Pagare, Boshi Huang, Mohini S. Ghatge, Abdelsattar M. Omar, Osheiza Abdulmalik, Yan Zhang, Martin K. Safo
Publikováno v:
Pharmaceutics, Vol 15, Iss 11, p 2547 (2023)
The synthetic allosteric effector of hemoglobin, TD-7 has been investigated as a potential therapeutic agent for the treatment of sickle cell disease. The pharmacologic activity of TD-7 is due to formation of a Schiff-base interaction between its ald
Externí odkaz:
https://doaj.org/article/e5e641785d274cb6a088cd67b1ee01dc
Autor:
Boshi Huang, Mohini S. Ghatge, Akua K. Donkor, Faik N. Musayev, Tanvi M. Deshpande, Mohammed Al-Awadh, Rana T. Alhashimi, Hongmei Zhu, Abdelsattar M. Omar, Marilyn J. Telen, Yan Zhang, Tim J. McMahon, Osheiza Abdulmalik, Martin K. Safo
Publikováno v:
Molecules, Vol 27, Iss 20, p 6835 (2022)
Sickle cell disease (SCD) is caused by a single-point mutation, and the ensuing deoxygenation-induced polymerization of sickle hemoglobin (HbS), and reduction in bioavailability of vascular nitric oxide (NO), contribute to the pathogenesis of the dis
Externí odkaz:
https://doaj.org/article/065bb1f3e66e489a8d47e684c10f8021
Autor:
Rana T. Alhashimi, Mohini S. Ghatge, Akua K. Donkor, Tanvi M. Deshpande, Nancy Anabaraonye, Dina Alramadhani, Richmond Danso-Danquah, Boshi Huang, Yan Zhang, Faik N. Musayev, Osheiza Abdulmalik, Martin K. Safo
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 696 (2022)
5-hydroxyfurfural (5HMF), an allosteric effector of hemoglobin (Hb) with an ability to increase Hb affinity for oxygen has been studied extensively for its antisickling effect in vitro and in vivo, and in humans for the treatment of sickle cell disea
Externí odkaz:
https://doaj.org/article/e86fec00e2774e248bc84f858cb480f1
Akademický článek
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Autor:
Anfal S. Aljahdali, Faik N. Musayev, John W. Burgner, Mohini S. Ghatge, Vibha Shekar, Yan Zhang, Abdelsattar M. Omar, Martin K. Safo
Publikováno v:
Acta Crystallographica Section D Structural Biology. 78:472-482
Bisphosphoglycerate mutase (BPGM) is an erythrocyte-specific multifunctional enzyme that is responsible for the regulation of 2,3-bisphosphoglycerate (2,3-BPG) in red blood cells through its synthase and phosphatase activities; the latter enzymatic f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd22cc0a33fa0732bd83c045ad82f58
https://doi.org/10.1107/s2059798322001802
https://doi.org/10.1107/s2059798322001802
Publikováno v:
Cureus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42c548c4c0ec16203e9fd67f0eacc71d
https://doi.org/10.7759/cureus.36168
https://doi.org/10.7759/cureus.36168
Autor:
Abdelsattar M. Omar, Osheiza Abdulmalik, Mohini S. Ghatge, Yosra A. Muhammad, Steven D. Paredes, Moustafa E. El-Araby, Martin K. Safo
Publikováno v:
Biomolecules, Vol 10, Iss 11, p 1508 (2020)
Aromatic aldehydes that bind to sickle hemoglobin (HbS) to increase the protein oxygen affinity and/or directly inhibit HbS polymer formation to prevent the pathological hypoxia-induced HbS polymerization and the subsequent erythrocyte sickling have
Externí odkaz:
https://doaj.org/article/b3322b5bdc3b4c949d8736deafb25c05
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 642
Pyridoxal 5′-phosphate (PLP), the active form of vitamin B6, serves as a cofactor for scores of B6-dependent (PLP-dependent) enzymes involved in many cellular processes. One such B6 enzyme is dopa decarboxylase (DDC), which is required for the bios
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ddbe381b7c82a86f55191ed88f02f0e
https://pubmed.ncbi.nlm.nih.gov/36614085
https://pubmed.ncbi.nlm.nih.gov/36614085
Publikováno v:
Sugar Tech. 24:551-562
This study aimed to determine the greenhouse gases (GHGs) emissions from the sugarcane crop, sugar and jaggery production. Also, it highlights the opportunities to minimize the GHGs emissions from the sugarcane cultivation. The required data were col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8a0dd7d89b665e9b595a38691b7abfb
https://doi.org/10.1007/s12355-021-01046-7
https://doi.org/10.1007/s12355-021-01046-7
Autor:
Angela Tramonti, Mohini S. Ghatge, Jill T. Babor, Faik N. Musayev, Martino Luigi di Salvo, Anna Barile, Gianni Colotti, Alessandra Giorgi, Steven D. Paredes, Akua K. Donkor, Mohammed H. Al Mughram, Valérie de Crécy‐Lagard, Martin K. Safo, Roberto Contestabile
Publikováno v:
Protein Science. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f1d280071cda43375a425e6eeb9a338
https://doi.org/10.1002/pro.4471
https://doi.org/10.1002/pro.4471