Zobrazeno 1 - 10
of 100
pro vyhledávání: '"S, Geisse"'
Autor:
S Geisse, Anne T. Bruinvels, Bernd Sommer, Mark D. Tricklebank, Daniel Hoyer, Lucien Gazi, E. Schüpbach, Philippe Schoeffter, M Danzeisen, I. Bobirnac
Publikováno v:
British Journal of Pharmacology. 124:889-896
1. Dopamine D4 receptor antagonists are being developed by several pharmaceutical companies as putative novel antipsychotics, possibly with low propensity to side-effects. Two such compounds, L-745,870 and U-101958 have been recently introduced. 2. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9beb34fff9900f03be289828f507c57d
https://doi.org/10.1038/sj.bjp.0701921
https://doi.org/10.1038/sj.bjp.0701921
Publikováno v:
Journal of Biological Chemistry. 266:19469-19474
It is recognized that insulin-like growth factors (IGFs) are bound to specific high-affinity insulin-like growth factor-binding proteins (IGFBPs). The role of IGFBPs in bone metabolism is not well established. The effect of recombinant human [Cys281]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ed5d8a8c4f35ffe4a850077c1dded08
https://doi.org/10.1016/s0021-9258(18)55019-5
https://doi.org/10.1016/s0021-9258(18)55019-5
Publikováno v:
Animal Cell Technology Meets Genomics ISBN: 9781402027918
Expression of recombinant proteins using mammalian expression systems is still considered to be costly, tedious and labour-intensive, and thus disadvantageous to high throughput applications. However, a breakthrough in the rapid generation of recombi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b94a4538cc9fb29df85ea50b75ae434
https://doi.org/10.1007/1-4020-3103-3_73
https://doi.org/10.1007/1-4020-3103-3_73
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 293(2)
Nateglinide (A-4166) is an amino acid derivative with insulinotrophic action in clinical development for treatment of type 2 diabetes. The aim of this study was to determine whether nateglinide's interaction at the K(ATP) channel/sulfonylurea recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81099ad377f943b75fa6cc2189fac99d
https://pubmed.ncbi.nlm.nih.gov/10773014
https://pubmed.ncbi.nlm.nih.gov/10773014
Autor:
S, Geisse, H P, Kocher
Publikováno v:
Methods in enzymology. 306
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::194f17994e4a186cf77594b57a8c8256
https://pubmed.ncbi.nlm.nih.gov/10432446
https://pubmed.ncbi.nlm.nih.gov/10432446
Publikováno v:
The Journal of biological chemistry. 266(29)
It is recognized that insulin-like growth factors (IGFs) are bound to specific high-affinity insulin-like growth factor-binding proteins (IGFBPs). The role of IGFBPs in bone metabolism is not well established. The effect of recombinant human [Cys281]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8fb873f0ec406251cc032f421ad0023f
https://pubmed.ncbi.nlm.nih.gov/1717466
https://pubmed.ncbi.nlm.nih.gov/1717466
Publikováno v:
Lymphokine and cytokine research. 10(4)
The human interleukin-3 gene was cloned in 1986 and the biochemical and biological properties of recombinant human interleukin-3 (rhuIL-3) protein were described. In this report we compare rhuIL-3 with nonrecombinant, natural huIL-3, purified from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12a06c7b22ca573374bfe0573fd04590
https://pubmed.ncbi.nlm.nih.gov/1932378
https://pubmed.ncbi.nlm.nih.gov/1932378
Publikováno v:
The New biologist. 3(3)
The structurally unrelated immunosuppressive drugs cyclosporin A (Sandimmun) and FK-506 both interfere with the process of T-cell proliferation by blocking the transcription of the T-cell growth factor interleukin-2 (IL-2). Here we demonstrate that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f51898c704a73b74416c4146d5f6f37d
https://pubmed.ncbi.nlm.nih.gov/1715185
https://pubmed.ncbi.nlm.nih.gov/1715185
Publikováno v:
Molecular and Cellular Biology. 5:3617-3620
An activated human Ha-ras gene was present in a secondary NIH 3T3 transformant isolated after serial transfection of originally low-molecular-weight DNA fragments from normal human cells. This gene appeared to have acquired its transforming propertie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db1dec8e1dc00c1433addf8a72544e0
https://doi.org/10.1128/mcb.5.12.3617-3620.1985
https://doi.org/10.1128/mcb.5.12.3617-3620.1985
Publikováno v:
Journal of Cellular Biochemistry. 34:31-38
The transcriptional activity of ten cellular oncogenes was analyzed in somatic cell hybrids that had been obtained after fusion of tumorigenic Chinese hamster cells and normal mouse fibroblasts. The hybrids showed either the tumorigenic or the nontum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6794b9139feb7a95ffbf546f8e90277
https://doi.org/10.1002/jcb.240340105
https://doi.org/10.1002/jcb.240340105