Zobrazeno 1 - 10
of 426
pro vyhledávání: '"S, Garfield"'
Autor:
Kim Moorwood, Florentia M. Smith, Alastair S. Garfield, Michael Cowley, Lowenna J. Holt, Roger J. Daly, Andrew Ward
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Background The growth factor receptor bound protein 7 (Grb7) family of signalling adaptor proteins comprises Grb7, Grb10 and Grb14. Each can interact with the insulin receptor and other receptor tyrosine kinases, where Grb10 and Grb14 inhibi
Externí odkaz:
https://doaj.org/article/4301b2953b36487aa2e022180b9e1406
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Optimal size at birth dictates perinatal survival and long-term risk of developing common disorders such as obesity, type 2 diabetes and cardiovascular disease. The imprinted Grb10 gene encodes a signalling adaptor protein capable
Externí odkaz:
https://doaj.org/article/80426d901c44433b99dc7cd4083ac2c0
Publikováno v:
Trends in Molecular Medicine. 29:152-172
Adenosine triphosphate (ATP)-binding cassette (ABC) transporters are a 48-member superfamily of membrane proteins that actively transport a variety of biological substrates across lipid membranes. Their functional diversity defines an expansive invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7abe7f4ed4225e463d9aad8748ea20
https://doi.org/10.1016/j.molmed.2022.11.001
https://doi.org/10.1016/j.molmed.2022.11.001
Autor:
S Abdelaziz, S Garfield, M McLeod, J Norton, J Lloyd, C Wheeler, A L Neves, J van Dael, B D Franklin
Publikováno v:
International Journal of Pharmacy Practice. 31:i3-i5
Introduction Technologies such as electronic prescribing, clinical decision support systems, and electronic medication dispensers, are increasingly being introduced into healthcare. Existing toolkits focus on the implementation of such technologies,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d50216be97e4548a9b61846d1a7443e
https://doi.org/10.1093/ijpp/riad021.004
https://doi.org/10.1093/ijpp/riad021.004
Autor:
A.J. Saxton, A. Chang, C. Cribbs, N. Franks, J.C. Valdoz, S. Garfield, D. Downs, H. Hepworth, M. Kobe, M.B. Scholand, G. Raghu, S. Narayanan, P.M. Van Ry
Publikováno v:
D29. TRANSLATIONAL RESEARCH IN IPF.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec7bb6a5a5852bfb8bb96b94cdf8485f
https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6481
https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6481
Autor:
Malgorzata S. Martin-Gronert, Claire J. Stocker, Edward T. Wargent, Roselle L. Cripps, Alastair S. Garfield, Zorica Jovanovic, Giuseppe D'Agostino, Giles S. H. Yeo, Michael A. Cawthorne, Jonathan R. S. Arch, Lora K. Heisler, Susan E. Ozanne
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 4, Pp 401-412 (2016)
Although obesity is a global epidemic, the physiological mechanisms involved are not well understood. Recent advances reveal that susceptibility to obesity can be programmed by maternal and neonatal nutrition. Specifically, a maternal low-protein die
Externí odkaz:
https://doaj.org/article/0d53f972d902400bac1f603ea96b7d98
Autor:
Luke K. Burke, Barbora Doslikova, Giuseppe D'Agostino, Megan Greenwald-Yarnell, Teodora Georgescu, Raffaella Chianese, Pablo B. Martinez de Morentin, Emmanuel Ogunnowo-Bada, Celine Cansell, Lourdes Valencia-Torres, Alastair S. Garfield, John Apergis-Schoute, Daniel D. Lam, John R. Speakman, Marcelo Rubinstein, Malcolm J. Low, Justin J. Rochford, Martin G. Myers, Mark L. Evans, Lora K. Heisler
Publikováno v:
Molecular Metabolism, Vol 5, Iss 3, Pp 245-252 (2016)
Objective: Obesity is one of the primary healthcare challenges of the 21st century. Signals relaying information regarding energy needs are integrated within the brain to influence body weight. Central among these integration nodes are the brain pro-
Externí odkaz:
https://doaj.org/article/c6e907e380bc4741a86d183bf11641af
Publikováno v:
International Journal of Pharmacy Practice. 31:i17-i18
Introduction Previous studies have shown that informal carers involved in assisting with patients’ medicines have considerable knowledge about patients’ usual medication management (1). This could be helpful for healthcare professionals (HCPs) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bc601fb8ced5945caeed61dc853fdb4
https://doi.org/10.1093/ijpp/riad021.019
https://doi.org/10.1093/ijpp/riad021.019
Autor:
Shubh Sharma, Alastair S. Garfield, Bhavik Shah, Patrick Kleyn, Ilia Ichetovkin, Ida Hatoum Moeller, William R. Mowrey, Lex H.T. Van der Ploeg
Publikováno v:
Molecules, Vol 24, Iss 10, p 1892 (2019)
In this work we summarize our understanding of melanocortin 4 receptor (MC4R) pathway activation, aiming to define a safe and effective therapeutic targeting strategy for the MC4R. Delineation of cellular MC4R pathways has provided evidence for disti
Externí odkaz:
https://doaj.org/article/ecd4ab8fa303454aad6be67707f506ff
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::126d5f6c82f5181cdcf27faf5d61e55e
https://doi.org/10.1530/endoabs.81.ep357
https://doi.org/10.1530/endoabs.81.ep357