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Akademický článek
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Autor:
van der Molen, Tjitse1,2 (AUTHOR) tjitse@ucsb.edu, Lim, Max1,2 (AUTHOR), Bartram, Julian3 (AUTHOR), Cheng, Zhuowei4 (AUTHOR), Robbins, Ash5 (AUTHOR), Parks, David F.6 (AUTHOR), Petzold, Linda R.4 (AUTHOR), Hierlemann, Andreas3 (AUTHOR), Haussler, David6,7,8 (AUTHOR), Hansma, Paul K.1,9 (AUTHOR), Tovar, Kenneth R.1 (AUTHOR), Kosik, Kenneth S.1,2 (AUTHOR)
Publikováno v:
PLoS ONE. 12/5/2024, Vol. 19 Issue 12, p1-36. 36p.
Autor:
Aimagambetova, Gulzhanat1 (AUTHOR) gulzhanat.aimagambetova@nu.edu.kz, Bapayeva, Gauri2 (AUTHOR) talshynu@yandex.ru, Ukybassova, Talshyn2 (AUTHOR), Kamzayeva, Nazira2 (AUTHOR), Sakhipova, Gulnara3 (AUTHOR), Shanazarov, Nasrulla4 (AUTHOR), Terzic, Milan1,2 (AUTHOR)
Publikováno v:
Journal of Clinical Medicine. Nov2024, Vol. 13 Issue 21, p6318. 16p.
Autor:
Heidi R. Bokesch, Jennifer A. Wilson, Curtis J. Henrich, Tanya R. Johnson, Ekaterina I. Goncharova, Kentaro Takada, James B. McMahon, Kirk R. Gustafson, Roberta S. Gardella
Publikováno v:
Chemical Biology & Drug Design. 69:321-330
Development of modulators of constitutively active, kinase domain mutants of c-Kit has proved to be very difficult. Therefore, a high-throughput differential cytotoxicity assay was developed to screen for compounds that preferentially kill cells expr
Autor:
James R. Vasselli, Tawnya C. McKee, James B. McMahon, W. Marston Linehan, Roberta S. Gardella, Girma M. Woldemichael
Publikováno v:
SLAS Discovery. 11:678-687
Reporter cell lines have been developed for the identification of inhibitors of gene expression enhanced by hypoxia-inducible factor 2, which has been implicated as a transcription factor involved in the tumorigenesis of clear cell renal carcinoma. S
Autor:
Michael R. Boyd, Tawnya C. McKee, Gregory M. L. Patterson, Roberta S. Gardella, Lewis K. Pannell, Karen Watson, Heidi R. Bokesch, Raymond C. Sowder, Robert W. Buckheit, Barry R. O'Keefe, Jim A. Turpin
Publikováno v:
Biochemistry. 42:2578-2584
A new anti-HIV protein, scytovirin, was isolated from aqueous extracts of the cultured cyanobacterium Scytonema varium. The protein displayed potent anticytopathic activity against laboratory strains and primary isolates of HIV-1 with EC50 values ran
Autor:
George R. Pettit, Sylvie Ducki, Rui Tan, Roberta S. Gardella, James B. McMahon, Michael R. Boyd, Peter M. Blumberg, Nancy E. Lewin, Dennis L. Doubek, Larry P. Tackett, Michael D. Williams
Publikováno v:
Journal of Natural Products. 65:1262-1265
A new cancer cell growth inhibitor designated pedilstatin (1) was isolated from a Republic of Maldives Pedilanthus sp. The structure was determined to be 13-O-acetyl-12-O-[2'Z,4'E-octadienoyl]-4alpha-deoxyphorbol on the basis of high-resolution mass
Autor:
Randy A. Buzzell, Barry R. O'Keefe, Danielle Robbins, Jennifer A. Wilson, James B. McMahon, Tanya R. Johnson, Michael R. Boyd, John A. Beutler, Roberta S. Gardella
Publikováno v:
SLAS Discovery. 7:105-110
The human immunodeficiency virus type-1 (HIV-1) envelope glycoprotein gp41 is an important mediator of viral entry into host cells. Previous studies showed that the virucidal protein cyanovirin-N (CV-N) bound to both gp120 and gp41, and that this bin