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Akademický článek

Unraveling the blood transcriptome after real-life exposure of Wistar-rats to PM2.5, PM1 and water-soluble metals in the ambient air

Autor: Ilias S. Frydas, Marianthi Kermenidou, Olga Tsave, Athanasios Salifoglou, Dimosthenis A. Sarigiannis

Publikováno v: Toxicology Reports, Vol 7, Iss , Pp 1469-1479 (2020)

Exposure to particulate matter (PM) is one of the most important environmental issues in Europe with major health impact. Various sizes of PM are suspended in the atmosphere and contributes to ambient air pollution. The current study aimed to explore

Externí odkaz: https://doaj.org/article/ee635a402f094553a16a3fcc1535bf4a

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Akademický článek

Impact of Mast Cells in Rejection of Allografts

Autor: S.K. Kritas, A. Saggini, G. Varvara, G. Murmura, A. Caraffa, P. Antinolfi, E. Tomato, A. Pantalone, G. Neri, S. Frydas, M. Rosati, M. Tei, A. Speziali, R. Saggini, F. Pandolfi, G. Cerulli, T.C. Theoharides, P. Conti

Publikováno v: European Journal of Inflammation, Vol 11 (2013)

Mast cells in the tissue are located close to nerves in and around the small vessels where they orchestrate important immune response after antigen recognition through Toll-like receptors. Mast cells can activate T and B lymphocytes and dendritic cel

Externí odkaz: https://doaj.org/article/da05e8b62d744bafbbc1091d2fb76335

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Akademický článek

Induction of CCL2 (MCP-1) BY IL-33 in Human Umbelical Cord Blood Mast Cells

Publikováno v: European Journal of Inflammation, Vol 10 (2012)

Mast cells, which derive from a bone marrow progenitor and mature in tissues, are important for allergic reactions, but also in inflammation, autoimmunity, and T-cell-mediated immune responses. The addition of certain cytokines to human umbilical cor

Externí odkaz: https://doaj.org/article/73ba75a6a3ee474ca56a270bc4338f09

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Akademický článek

Calcium Ionophore A23187 and Compound 48/80 Induce PGD2 and Tryptase in Human Cord Blood-Derived Mast Cells: Lack of Effect of IL-18

Autor: G. Maccauro, D. Tripodi, A. Saggini, F. Conti, E. Cianchetti, D. Angelucci, M. Rosati, E. Toniato, M. Fulcheri, S. Tetè, V. Salini, A. Caraffa, P. Antinolfi, S. Frydas, P. Conti, T.C. Theoharides

Publikováno v: European Journal of Inflammation, Vol 10 (2012)

Immunological and biochemical reactions associated with inflammation are elicited in response to a physical or immunological challenge. Early in inflammation there is mobilization and infiltration of neutrophils, mast cells and macrophages to the sit

Externí odkaz: https://doaj.org/article/2e79f04f980a4f8e8f538e41e53e0c37

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Akademický článek

Cholesterol: An Inflammatory Compound

Autor: A. Saggini, A. Anogeianaki, D. Angelucci, E. Cianchetti, M. D'Alessandro, G. Maccauro, V. Salini, A. Caraffa, S. Teté, F. Conti, D. Tripodi, M. Fulcheri, S. Frydas, M. Rosati, Y.B. Shaik-Dasthagirisaheb

Publikováno v: European Journal of Inflammation, Vol 9 (2011)

Obesity is one of the main rising causes of health problems in modern society and is correlated to type 2 diabetes mellitus, hypertension, heart disease and atherosclerosis. Bacterial products, endogenous substances such as oxidized LDL (ox-LDL) and

Externí odkaz: https://doaj.org/article/ff331e987f634e3484c23e57be103c27

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Akademický článek

Susceptibility and Resistance to Canine Leishmaniose is Associated to Polymorphisms of the Canine TNF-α Gene

Autor: I. Symeonidou, M. Hatzistilianou, E. Papadopoulos, C.I. Dovas, E. Karagouni, S. Pappa, C.N. Pantzartzi, A. Kourelis, S. Frydas

Publikováno v: European Journal of Inflammation, Vol 9 (2011)

The prevalence of canine leishmaniosis (CanL) infection in an enzootic area is considerably higher than the overall prevalence of the disease, suggesting a role of host genetics related to the outcome of the disease. It is accepted that one determini

Externí odkaz: https://doaj.org/article/3c5a3758e9dd4e879cd251843736eb99

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Akademický článek

IL-34 a Newly Discovered Cytokine

Autor: M.L. Castellani, A. Anogeianaki, P. Felaco, E. Toniato, M.A. De Lutiis, B. Shaik, M. Fulcheri, J. Vecchiet, S. Tetè, V. Salini, T.C. Theoharides, A. Caraffa, P. Antinolfi, S. Frydas, P. Conti, C. Cuccurullo, C. Ciampoli, G. Cerulli

Publikováno v: European Journal of Inflammation, Vol 8 (2010)

In this study we describe some biological effects of IL-34, a newly discovered cytokine. We show that Il-34 stimulates monocyte cell viability and directly modulates the number and function of monocytes and regulates myeloid cell growth and different

Externí odkaz: https://doaj.org/article/cdfd77cd84f34ffb8c81a90bb4076f4b

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Akademický článek

Chemokines and Their Role in Parasitic Diseases

Autor: S. Frydas, E. Karagouni, E. Papadopoulos, M. Hatzistilianou, S. Pappas, N. Papaioannou

Publikováno v: European Journal of Inflammation, Vol 2 (2004)

Chemotactic cytokines (chemokines), the intercellular mediators, produced and released by a wide variety of cell types, are a group of small secreted proteins (8–10 KDa), which mediate host response to invading organisms (viruses, bacteria, parasit

Externí odkaz: https://doaj.org/article/fcabb6db1a78479ca4bf1a12a1770a43

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