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pro vyhledávání: '"S, Dupin"'
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Autor:
Graham P. Jones, Isabelle V. S. Dupin, Corey Ryan, Andrew J. Markides, Muryel Boulay, Elizabeth J. Waters, Brett M. McKinnon, Patrick J. Williams
Publikováno v:
Journal of Agricultural and Food Chemistry. 48:3098-3105
A fraction containing the mannoproteins released during fermentation from the winemaking strain of Saccharomyces cerevisiae, Maurivin PDM, was able to reduce the visible protein haze in white wine. This fraction of haze protective mannoprotein materi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f17168547c9acb8a4d87a25eb6825b2
https://doi.org/10.1021/jf0002443
https://doi.org/10.1021/jf0002443
Autor:
Isabelle V. S. Dupin, Patrick J. Williams, Elizabeth J. Waters, and Andrew J. Markides, Graham P. Jones, Vanessa J. Stockdale
Publikováno v:
Journal of Agricultural and Food Chemistry. 48:1086-1095
Yeast-derived haze-protective mannoprotein material (HPM) offers protection to white wines from commercially unacceptable turbidities. HPM extraction methods have been evaluated using three winemaking strains of Saccharomyces cerevisiae. Digestion wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206033e35e2413be26958f9aea843871
https://doi.org/10.1021/jf9905020
https://doi.org/10.1021/jf9905020
Publikováno v:
Journal of Pharmaceutical Sciences. 86:584-590
In this study, we investigated rational and reliable methods of using animal data to predict in humans the clearance of drugs which are mainly eliminated through hepatic metabolism. For 10 extensively metabolized compounds, adjusting the in vivo clea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40132a37cc56e1b2c95d8bf318e691a
https://doi.org/10.1021/js960440h
https://doi.org/10.1021/js960440h
Autor:
D. Jaeck, Ruby C. Chou, Geneviève Ubeaud, Ph. Coassolo, B. Vallès, S. Dupin, T. Lave, Christophe Schmitt
Publikováno v:
Pharmaceutical Research. 14:152-155
Purpose. The present investigation retrospectively evaluates the use of human hepatocytes to classify compounds into low, intermediate or high hepatic extraction ratio in man.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32836b292c2416a5764bd705f578d43f
https://doi.org/10.1023/a:1012036324237
https://doi.org/10.1023/a:1012036324237
Autor:
Ruby C. Chou, B. Morgenroth, J. Meyer, D. Jaeck, M. Kapps, M. Schmitt, T. Lave, S. Dupin, Ph. Coassolo
Publikováno v:
Xenobiotica. 26:839-851
1. In the present study, in vivo pharmacokinetic data in animals were combined with in vitro metabolic data from animal and human hepatocytes to predict the human systemic plasma clearance and the kinetic profile of tolcapone, a compound metabolized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b64729b49e5fbd36a20955d1f97304
https://doi.org/10.3109/00498259609046754
https://doi.org/10.3109/00498259609046754
Publikováno v:
Pharmaceutical Research. 11:835-838
The aim of the present study was to compare the performance of conventional equilibrium dialysis method with a microdialysis method in studying drug protein binding. The two methods were assessed by comparing the measured mean unbound drug fraction i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc3ccf5ed054ce1570a132710d134892
https://doi.org/10.1023/a:1018973607051
https://doi.org/10.1023/a:1018973607051
Autor:
Claude Tapiero, Isabelle V. S. Dupin, Jean C. Sapis, Oubadjim. M'Bairaroua, Claude L. Bayonove, Ziya Günata
Publikováno v:
Journal of Agricultural and Food Chemistry. 40:1886-1891
Various aspects of fungus-originated β-apiosidase were studied. The production of the enzyme on various carbon sources by fungi appeared to be inducible as it was only produced when apiin, an apiosylglucoside, was present in the culture medium. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12f54b5bc7dc54edcfb4bde24790cda8
https://doi.org/10.1021/jf00022a032
https://doi.org/10.1021/jf00022a032
Publikováno v:
Pharmaceutical research. 14(2)
The present investigation retrospectively evaluates the use of human hepatocytes to classify compounds into low, intermediate or high hepatic extraction ratio in man.A simple approach was used to correlate the in vivo hepatic extraction ratio of a nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a5bc651740ff477b99ed7409fb9c4d5
https://pubmed.ncbi.nlm.nih.gov/9090701
https://pubmed.ncbi.nlm.nih.gov/9090701
Publikováno v:
Pharmaceutical research. 13(1)
The goal of this study was to find a rational and reliable method of using animal data to predict the clearance of metabolised drugs in humans.One such approach is to use in vitro liver models (e.g. hepatocytes and microsomes) to determine the relati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04ed4eb116d3411b289ae6dd4ed5ca81
https://pubmed.ncbi.nlm.nih.gov/8668687
https://pubmed.ncbi.nlm.nih.gov/8668687