Zobrazeno 1 - 10
of 648
pro vyhledávání: '"S, Caputo"'
Autor:
Jaime Alvarez-Benayas, Nikolaos Trasanidis, Alexia Katsarou, Kanagaraju Ponnusamy, Aristeidis Chaidos, Philippa C. May, Xiaolin Xiao, Marco Bua, Maria Atta, Irene A. G. Roberts, Holger W. Auner, Evdoxia Hatjiharissi, Maria Papaioannou, Valentina S. Caputo, Ian M. Sudbery, Anastasios Karadimitris
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Despite extensive genetic heterogeneity, nearly half of all multiple myeloma (MM) cases are driven by cyclin D2 (CCND2) over-expression. Here the authors dissect the chromatin landscape of MM to provide insights into the transcriptional regulatory la
Externí odkaz:
https://doaj.org/article/3fcdca45e3ee4529b529898c605a8394
Autor:
Alena Machuldova, Monika Holubova, Valentina S. Caputo, Miroslava Cedikova, Pavel Jindra, Lucie Houdova, Pavel Pitule
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Natural killer cells possess key regulatory function in various malignant diseases, including acute myeloid leukemia. NK cell activity is driven by signals received through ligands binding activating or inhibitory receptors. Their activity towards el
Externí odkaz:
https://doaj.org/article/7f5e4c10b31c466bb224c23b27d3d567
Autor:
Kanagaraju Ponnusamy, Maria Myrsini Tzioni, Murshida Begum, Mark E. Robinson, Valentina S. Caputo, Alexia Katsarou, Nikolaos Trasanidis, Xiaolin Xiao, Ioannis V. Kostopoulos, Deena Iskander, Irene Roberts, Pritesh Trivedi, Holger W. Auner, Kikkeri Naresh, Aristeidis Chaidos, Anastasios Karadimitris
Publikováno v:
Haematologica, Vol 107, Iss 3 (2021)
Multiple myeloma is a malignancy of plasma cells initiated and driven by primary and secondary genetic events. However, myeloma plasma cell survival and proliferation might be sustained by non-genetic drivers. Z-DNA-binding protein 1 (ZBP1; also know
Externí odkaz:
https://doaj.org/article/c3be2fdb2bb54d6ea4938d0fa843b835
Autor:
Valentina S. Caputo, Nikolaos Trasanidis, Xiaolin Xiao, Mark E. Robinson, Alexia Katsarou, Kanagaraju Ponnusamy, Rab K. Prinjha, Nicholas Smithers, Aristeidis Chaidos, Holger W. Auner, Anastasios Karadimitris
Publikováno v:
iScience, Vol 24, Iss 1, Pp 101989- (2021)
Summary: Osteoclast (OC) development in response to nuclear factor kappa-Β ligand (RANKL) is critical for bone homeostasis in health and in disease. The early and direct chromatin regulatory changes imparted by the BET chromatin readers Brd2-4 and O
Externí odkaz:
https://doaj.org/article/5937c26f23c24a70a47ad818b646ebb2
Autor:
Pavel Ostasov, Henry Robertson, Paolo Piazza, Avik Datta, Jane Apperley, Lucie Houdova, Daniel Lysak, Monika Holubova, Katerina Tesarova, Valentina S. Caputo, Iros Barozzi
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Genetic and transcriptional heterogeneity of Chronic lymphocytic leukaemia (CLL) limits prevention of disease progression. Longitudinal single-cell transcriptomics represents the state-of-the-art method to profile the disease heterogeneity at diagnos
Externí odkaz:
https://doaj.org/article/aa9fd42a7eec4cb5bc9c63eda042ba23
Autor:
Alexia Katsarou, Nikolaos Trasanidis, Kanagaraju Ponnusamy, Ioannis V Kostopoulos, Jaime Alvarez-Benayas, Foteini Papaleonidopoulou, Keren Keren, Pierangela MR Sabbattini, Niklas Feldhahn, Maria Papaioannou, Evdoxia Hatjiharissi, Ian M Sudbery, Aristeidis Chaidos, Valentina S Caputo, Anastasios Karadimitris
Publikováno v:
Blood Advances.
Deregulated expression of lineage-affiliated transcription factors is a major mechanism of oncogenesis. However, how deregulation of non-lineage affiliated TF impacts chromatin to initiate oncogenic transcriptional programmes is not well known. To ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9469167e485cfe741dfcc1309b8d0b01
https://doi.org/10.1182/bloodadvances.2023009772
https://doi.org/10.1182/bloodadvances.2023009772
Autor:
S Caputo, G Blair, G Hampel, J Greenberg, B Herzog, T Nguyen, W Almajed, S Sikka, W Hellstrom
Publikováno v:
The Journal of Sexual Medicine. 20
Introduction The IMPRESS trial revealed that intralesional collagenase clostridium histolyticum, Xiaflex, is safe and efficacious for treating the physical and subjective effects of Peyronie’s Disease (PD). However, little is known about the other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbc72af4e94c3401d9cb35cc905fc591
https://doi.org/10.1093/jsxmed/qdad060.156
https://doi.org/10.1093/jsxmed/qdad060.156
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