Zobrazeno 1 - 10
of 1 348
pro vyhledávání: '"S, Brack"'
Publikováno v:
eLife, Vol 11 (2022)
The quiescent muscle stem cell (QSC) pool is heterogeneous and generally characterized by the presence and levels of intrinsic myogenic transcription factors. Whether extrinsic factors maintain the diversity of states across the QSC pool remains unkn
Externí odkaz:
https://doaj.org/article/6161cb6243494aedb6f5e9b29e658b79
Autor:
Emilie Barruet, Steven M Garcia, Katharine Striedinger, Jake Wu, Solomon Lee, Lauren Byrnes, Alvin Wong, Sun Xuefeng, Stanley Tamaki, Andrew S Brack, Jason H Pomerantz
Publikováno v:
eLife, Vol 9 (2020)
Although heterogeneity is recognized within the murine satellite cell pool, a comprehensive understanding of distinct subpopulations and their functional relevance in human satellite cells is lacking. We used a combination of single cell RNA sequenci
Externí odkaz:
https://doaj.org/article/5697e4aa60ac459c93de99abd3ea4723
Supplementary Tables S1-3, Figure S1 from Tumor-Targeting Properties of Novel Antibodies Specific to the Large Isoform of Tenascin-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff6eff77291cfdef04253e8c45b2eae
https://doi.org/10.1158/1078-0432.22441483
https://doi.org/10.1158/1078-0432.22441483
Data from Tumor-Targeting Properties of Novel Antibodies Specific to the Large Isoform of Tenascin-C
Background: The targeted delivery of bioactive molecules with antibodies specific to tumor-associated antigens represents a promising strategy for improving the efficacy of tumor therapy. The large isoform of tenascin-C, an abundant glycoprotein of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0675da42a583b7b29c6ff38b15813e16
https://doi.org/10.1158/1078-0432.c.6518539
https://doi.org/10.1158/1078-0432.c.6518539
Publikováno v:
Stem Cell Reports, Vol 4, Iss 6, Pp 1061-1074 (2015)
To ensure accurate genomic segregation, cells evolved the spindle assembly checkpoint (SAC), whose role in adult stem cells remains unknown. Inducible perturbation of a SAC kinase, Mps1, and its downstream effector, Mad2, in skeletal muscle stem cell
Externí odkaz:
https://doaj.org/article/0c71acc5f0584be8bbb8ddbd6d45003a
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 1, p e1005927 (2018)
Cell populations display heterogeneous and dynamic phenotypic states at multiple scales. Similar to molecular features commonly used to explore cell heterogeneity, cell behavior is a rich phenotypic space that may allow for identification of relevant
Externí odkaz:
https://doaj.org/article/7155a5a63bc740189f098f7284f912f6
Publikováno v:
eLife. 11
The quiescent muscle stem cell (QSC) pool is heterogeneous and generally characterized by the presence and levels of intrinsic myogenic transcription factors. Whether extrinsic factors maintain the diversity of states across the QSC pool remains unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136c77f4c3c1edbddef947c1108018bd
https://pubmed.ncbi.nlm.nih.gov/36583937
https://pubmed.ncbi.nlm.nih.gov/36583937
SummaryThe quiescent muscle stem cell (QSC) pool is heterogeneous and generally characterized by the presence and levels of intrinsic myogenic transcription factors. Whether extrinsic factors maintain the diversity of states across the QSC pool remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7337d6ba9dfddb978745ce63fe68b6fa
https://doi.org/10.1101/2020.10.20.347484
https://doi.org/10.1101/2020.10.20.347484
Autor:
Manmeet H. Raval, Pin-Chung Cheng, Nicholas Guardino, Sanjana Ahsan, Hao Zhou, Rajiv Lochan Tiwari, Lu Wang, Andrew Chareunsouk, Maxwell Ederer, Ara B. Hwang, Matt Ellenberger, Rob Pepin, Daniel Raftery, Daniel Promislow, Keyue Shen, Andrew S. Brack, Joseph T. Rodgers
Decline in the skeletal muscle stem cell (MuSC) function is a major contributor to age-associated impairments in muscle regeneration and function. The ability of MuSCs to activate (i.e. exit quiescence, enter the cell cycle, and divide) following inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d131a18ef953be98d7b655f1ee9d7b