Zobrazeno 1 - 10 of 148 pro vyhledávání: '"S, Boehrer"'
1
Suppression of the DNA damage response in acute myeloid leukemia versus myelodysplastic syndrome
Autor: Lorenzo Galluzzi, S. de Botton, Maximilien Tailler, Oliver G. Ottmann, Claude Gardin, Wolf-Karsten Hofmann, Martin Ruthardt, Nicolas Tajeddine, Lionel Adès, Sylvain Thepot, Gesine Bug, Ken A. Olaussen, C Fouassier, Pierre Fenaux, S. Boehrer, Guido Kroemer, Virginie Eclache, S. Kriener
Publikováno v: Oncogene. 28:2205-2218
The molecular mechanisms responsible for the evolution from the preleukemic entities of low-risk myelodysplastic syndrome (MDS) to the less favorable forms of high-risk MDS, as well as those enabling transformation to acute myeloid leukemia (AML), ar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4fa19a83a06ea8d135de401e76fd81
https://doi.org/10.1038/onc.2009.69
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2
Inhibition of Osteosarcoma Cell Proliferation by the Hedgehog-Inhibitor Cyclopamine
Autor: D. Percic, Jörg Warzecha, C. Brüning, S. Boehrer, S. Göttig, E. Brude, A. Kurth, K.U. Chow
Publikováno v: Journal of Chemotherapy. 19:554-561
Osteosarcomas (OS) are the most frequent primary malignant bone tumors in humans. Even though OS are chemosensitive, about 30% of patients must be considered poor responders and consequently have a dismal long term prognosis. The Hedgehog (Hh) gene i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7456ffef262d1c608f2752550029d1f
https://doi.org/10.1179/joc.2007.19.5.554
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4
Deregulated expression of prostate apoptosis response gene-4 in less differentiated lymphocytes and inverse expressional patterns of par-4 and bcl-2 in acute lymphocytic leukemia
Autor: S, Boehrer, K U, Chow, E, Puccetti, M, Ruthardt, S, Godzisard, A, Krapohl, B, Schneider, D, Hoelzer, P S, Mitrou, V M, Rangnekar, E, Weidmann
Publikováno v: The Hematology Journal. 2:103-107
Prostate apoptosis response gene-4, known as par-4, is a new proapoptotic factor functionally required but not sufficient for apoptosis. Since there is evidence from prostate cancer cells that par-4 is involved in regulation of bcl-2 we assessed expr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3febe8c0bb1e328e1ff5898f8ac4b61
https://doi.org/10.1038/sj.thj.6200089
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5
Antineoplastic activity of ouabain and pyrithione zinc in acute myeloid leukemia
Autor: Guido Kroemer, Elodie Lainey, Oliver Kepp, Lorenzo Galluzzi, Maximilien Tailler, Véronique Baud, Didier Métivier, Laura Senovilla, Marie Sebert, Sylvain Thepot, K Billot, Pierre Fenaux, S. Boehrer
Publikováno v: Oncogene. 31(30)
Despite recent progress in the treatment of acute myeloid leukemia (AML), the prognosis of this rather heterogeneous disease remains poor and novel chemotherapeutics that specifically target leukemic cells must be developed. To address this need at t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cac2a7e4f7483540f5b595efc2cb812
https://pubmed.ncbi.nlm.nih.gov/23752179
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8
In vitro induction of apoptosis of neoplastic cells in low-grade non-Hodgkin's lymphomas using combinations of established cytotoxic drugs with bendamustine
Autor: K U, Chow, S, Boehrer, K, Geduldig, A, Krapohl, D, Hoelzer, P S, Mitrou, E, Weidmann
Publikováno v: Haematologica. 86(5)
Regulation of apoptotic cell death is being increasingly recognized as a mechanisms by which cytostatic agents mediate tumor cell death. Preliminary clinical studies with bendamustine, an alkylating agent with a purine nucleus, provide strong evidenc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7b5097d8a1219d99e74db3cb484398a1
https://pubmed.ncbi.nlm.nih.gov/11410411
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9
T-large granular lymphocyte leukaemia with natural killer cell-like cytotoxicity and expression of two different alpha- and beta-T-cell receptor chains
Autor: S, Boehrer, T, Hinz, D, Schui, S, Harder, K U, Chow, B, Schneider, D, Hoelzer, P S, Mitrou, E, Weidmann
Publikováno v: British journal of haematology. 112(1)
We describe a case of cytotoxic T-large granular lymphocyte leukaemia showing typical morphological features, expressing antigens characteristic for cytotoxic T cells and exhibiting marked natural killer-like cytotoxicity towards different target cel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a60cce4c3c86def9c425ef6c5b091f41
https://pubmed.ncbi.nlm.nih.gov/11167803
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