Zobrazeno 1 - 10
of 63
pro vyhledávání: '"S, Bochmann"'
Publikováno v:
Pharmaceutics, Vol 10, Iss 3, p 132 (2018)
A validation for the use of model-based melt viscosity in hot-melt extrusion numerical simulations was presented. Here, the melt viscosity of an amorphous solid dispersion (ASD) was calculated by using its glass transition temperature (Tg) and the rh
Externí odkaz:
https://doaj.org/article/474cd3b02c694177b38485d9089386f3
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 141:149-160
The aim of this work was to investigate the relationship between formulation material properties, process parameters and process performance for the manufacturing of amorphous solid dispersions via hot-melt extrusion (HME) using experimentation coupl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6170d309782ae2313635c04b5840eb59
https://doi.org/10.1016/j.ejpb.2019.05.021
https://doi.org/10.1016/j.ejpb.2019.05.021
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 141:111-120
The number of models for assessing the solubility of active pharmaceutical ingredients (APIs) in polymeric matrices on the one hand and the extent of available associated data on the other hand has been rising steadily in the past few years. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5bb2682e18a4adf0ea06e02c1741c3e
https://doi.org/10.1016/j.ejpb.2019.05.012
https://doi.org/10.1016/j.ejpb.2019.05.012
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 119:47-55
The feasibility of predicting melt rheology by using the glass transition temperature (Tg) of a desired amorphous solid dispersion (ASD) for hot-melt extrusion (HME) and other melt based processes is presented. Three groups of three different active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ced4a73ca81be45cbeb7264d66e44923
https://doi.org/10.1016/j.ejpb.2017.05.010
https://doi.org/10.1016/j.ejpb.2017.05.010
Publikováno v:
European Journal of Pharmaceutical Sciences. 158:105682
In general, the erosion rate of copovidone-based amorphous solid dispersions (ASDs) in contact with water diminishes with increasing drug load, causing poor drug release from the final drug product. A new easy-to-use tool with low material- and time-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bb97f9d25d2b30acf82ee2ede63e04
https://doi.org/10.1016/j.ejps.2020.105682
https://doi.org/10.1016/j.ejps.2020.105682
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 119
The feasibility of predicting melt rheology by using the glass transition temperature (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b89316c5c22c7c6865c1db6637a11edb
https://pubmed.ncbi.nlm.nih.gov/28532677
https://pubmed.ncbi.nlm.nih.gov/28532677
Publikováno v:
Pharmaceutics
Volume 10
Issue 3
Pharmaceutics, Vol 10, Iss 3, p 132 (2018)
Volume 10
Issue 3
Pharmaceutics, Vol 10, Iss 3, p 132 (2018)
A validation for the use of model-based melt viscosity in hot-melt extrusion numerical simulations was presented. Here, the melt viscosity of an amorphous solid dispersion (ASD) was calculated by using its glass transition temperature (Tg) and the rh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df4eed9bd038b934b0f1e802de10b61
https://doi.org/10.3390/pharmaceutics10030132
https://doi.org/10.3390/pharmaceutics10030132
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