Zobrazeno 1 - 10
of 156
pro vyhledávání: '"S, Bhate"'
Autor:
Michael Y. Lee, Jacob S. Bedia, Salil S. Bhate, Graham L. Barlow, Darci Phillips, Wendy J. Fantl, Garry P. Nolan, Christian M. Schürch
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Background Algorithmic cellular segmentation is an essential step for the quantitative analysis of highly multiplexed tissue images. Current segmentation pipelines often require manual dataset annotation and additional training, significant
Externí odkaz:
https://doaj.org/article/347f6e2534b248438390ec26d6ecd71e
Autor:
Darci Phillips, Magdalena Matusiak, Belén Rivero Gutierrez, Salil S. Bhate, Graham L. Barlow, Sizun Jiang, Janos Demeter, Kimberly S. Smythe, Robert H. Pierce, Steven P. Fling, Nirasha Ramchurren, Martin A. Cheever, Yury Goltsev, Robert B. West, Michael S. Khodadoust, Youn H. Kim, Christian M. Schürch, Garry P. Nolan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
PD-1 blockade is effective for only a subset of patients with cutaneous T cell lymphomas. Here, the authors report a spatial biomarker that uses immune and cancer cell topography to predict response to PD-1 blockade in this disease.
Externí odkaz:
https://doaj.org/article/185b95b3ae0241efb2f75ef0ed8fba8c
Autor:
Aaron T. Mayer, Derek R. Holman, Anav Sood, Utkarsh Tandon, Salil S. Bhate, Sunil Bodapati, Graham L. Barlow, Jeff Chang, Sarah Black, Erica C. Crenshaw, Alexander N. Koron, Sarah E. Streett, Sanjiv S. Gambhir, William J. Sandborn, Brigid S. Boland, Trevor Hastie, Robert Tibshirani, John T. Chang, Garry P. Nolan, Christian M. Schürch, Stephan Rogalla
Publikováno v:
Science Advances. 9
Although literature suggests that resistance to TNF inhibitor (TNFi) therapy in patients with ulcerative colitis (UC) is partially linked to immune cell populations in the inflamed region, there is still substantial uncertainty underlying the relevan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c68a61e9230e2295426bb6254e237385
https://doi.org/10.1126/sciadv.add1166
https://doi.org/10.1126/sciadv.add1166
We develop a mathematical theory proposing that complex molecular phenotypes (CMPs, e.g., single-cell gene expression distributions and tissue organization) are produced from templates in the genome. We validate our theory using a procedure termed Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a988562b1aaed4e6229b91b659801de3
https://doi.org/10.1101/2022.08.15.503769
https://doi.org/10.1101/2022.08.15.503769
Autor:
Tala Shekarian, Carl P. Zinner, Ewelina M. Bartoszek, Wandrille Duchemin, Anna T. Wachnowicz, Sabrina Hogan, Manina M. Etter, Julia Flammer, Chiara Paganetti, Tomás A. Martins, Philip Schmassmann, Steven Zanganeh, Francois Le Goff, Manuele G. Muraro, Marie-Françoise Ritz, Darci Phillips, Salil S. Bhate, Graham L. Barlow, Garry P. Nolan, Christian M. Schürch, Gregor Hutter
Publikováno v:
Science advances. 8(26)
Recent therapeutic strategies for glioblastoma (GBM) aim at targeting immune tumor microenvironment (iTME) components to induce antitumoral immunity. A patient-tailored, ex vivo drug testing and response analysis platform for GBM would facilitate per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f60ca9adeac0138f529f65e10dd32b
https://pubmed.ncbi.nlm.nih.gov/35776791
https://pubmed.ncbi.nlm.nih.gov/35776791
Autor:
Lingraj V. Sargar, Ritesh S. Bhate, Ashapak M. Tamboli, Sagar S. Landage, Kaustubh V. Gavali, Sahebrao H. Shembade
Publikováno v:
International Journal of Pharmaceutical Sciences and Medicine. 6:52-63
A rapid and precise high performance liquid chromatography method has been developed for the validation of Salmeterol xinofoate in its pure dosage form. The separation was carried out on Agilent Zorbax Bonus RP- (250mm ×4.6mm 5μ) column with a mobi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4f77b0fc9c96a44f88df9c88ee4c44f
https://doi.org/10.47760/ijpsm.2021.v06i06.006
https://doi.org/10.47760/ijpsm.2021.v06i06.006
Akademický článek
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Autor:
Gustavo Vazquez, Salil S. Bhate, Yury Goltsev, Garry P. Nolan, Sarah Black, Christian M. Schürch, Nikolay Samusik, Graham L. Barlow, Julia Kennedy-Darling, John W. Hickey, Vishal G. Venkataraaman
Publikováno v:
European Journal of Immunology
Multiparameter tissue imaging enables analysis of cell‐cell interactions in situ, the cellular basis for tissue structure, and novel cell types that are spatially restricted, giving clues to biological mechanisms behind tissue homeostasis and disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a715b545549f0ae4c981bdb56dd208c
https://doi.org/10.1002/eji.202048891
https://doi.org/10.1002/eji.202048891
Publikováno v:
Medical Journal of Dr. D.Y. Patil University, Vol 6, Iss 1, Pp 75-78 (2013)
Context: Isolated systolic hypertension (ISH) is increasingly recognized as a cardiovascular risk factor. Increase in pulse pressure is a powerful independent predictor of cardiovascular events. Aims: To study the hypertensive changes by 2D echocardi
Externí odkaz:
https://doaj.org/article/a15d5cc12d604c6e98879c5e5222711f
Autor:
Kimberly S. Smythe, Darci J. Phillips, Robert H. Pierce, Salil S. Bhate, Yury Goltsev, Youn H. Kim, Magdalena Matusiak, Christian M. Schürch, Steven P. Fling, Garry P. Nolan, Martin A. Cheever, Janos Demeter, Graham L. Barlow, Sizun Jiang, Nirasha Ramchurren, Robert West, Michael S. Khodadoust, Belén Rivero Gutierrez
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Cutaneous T cell lymphomas (CTCL) are rare but aggressive cancers without effective treatments. While a subset of patients derive benefit from PD-1 blockade, there is a critically unmet need for predictive biomarkers of response. Herein, we perform C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f33281c9bc1e62f3375e6159928ba9b
http://europepmc.org/articles/PMC8602403
http://europepmc.org/articles/PMC8602403