Zobrazeno 1 - 10
of 1 432
pro vyhledávání: '"S, Bader"'
Autor:
Chun Zhou, Yun Wang, Yikun Huang, Yongpan An, Xian Fu, Daqian Yang, Yilin Wang, Jintao Zhang, Leslie A. Mitchell, Joel S. Bader, Yizhi Cai, Junbiao Dai, Jef D. Boeke, Zhiming Cai, Zhengwei Xie, Yue Shen, Weiren Huang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract In the era of synthetic biology, design, construction, and utilization of synthetic chromosomes with unique features provide a strategy to study complex cellular processes such as aging. Herein, we successfully construct the 884 Kb synXIII o
Externí odkaz:
https://doaj.org/article/60d909e6a81a4fc18ff20ea86b0148a3
Autor:
Florent Villiers, Yasir Suhail, Jade Lee, Felix Hauser, Jaeung Hwang, Joel S. Bader, John K. McKay, Scott C. Peck, Julian I. Schroeder, June M. Kwak
Publikováno v:
Stress Biology, Vol 4, Iss 1, Pp 1-17 (2024)
Abstract Drought has a significant, negative impact on crop production; and these effects are poised to increase with climate change. Plants acclimate to drought and water stress through diverse physiological responses, primarily mediated by the horm
Externí odkaz:
https://doaj.org/article/80ad85c095f04af18ea82357f448d4db
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 6, p e1012195 (2024)
Therapeutic interventions are designed to perturb the function of a biological system. However, there are many types of proteins that cannot be targeted with conventional small molecule drugs. Accordingly, many identified gene-regulatory drivers and
Externí odkaz:
https://doaj.org/article/02ea3ba2e69f4ad4996c9faec1975b45
Autor:
Aldo S. Bader, Martin Bushell
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract DNA double-strand breaks (DSBs) are the most mutagenic form of DNA damage, and play a significant role in cancer biology, neurodegeneration and aging. However, studying DSB-induced mutagenesis is limited by our current approaches. Here, we d
Externí odkaz:
https://doaj.org/article/8089aa688e564751af5ebfdc3ec128c8
Publikováno v:
European Psychiatry, Vol 67, Pp S376-S376 (2024)
Introduction Pregnancy and postpartum is an important life event associated with profound physiognomic and psychosocial changes affecting the female body in all its physiological, psychic and affective reality. It might influence the sexual function
Externí odkaz:
https://doaj.org/article/9225665ed4244845bb6897d8499544a8
Publikováno v:
European Psychiatry, Vol 67, Pp S382-S382 (2024)
Introduction Attention deficit hyperactivity disorder (ADHD) is a neurobehavioral disorder witch assumed to be a disorder of childhoood but recently has been shown to persist into adulthood. As in children, core features of adult ADHD include inatte
Externí odkaz:
https://doaj.org/article/393fe4c7b0994c26b3ec905b1c2ef6e2
Publikováno v:
European Psychiatry, Vol 67, Pp S266-S267 (2024)
Introduction Pregnancy,postpartum and breastfeeding is a very challenging period in the women’s life. Many shared false beliefs and perceptions about this period can influence a pregnant woman’s sexual life and couple. Objectives to explore se
Externí odkaz:
https://doaj.org/article/851b9c6ae33540d4a7f8461520cafe0d
Publikováno v:
European Psychiatry, Vol 67, Pp S624-S624 (2024)
Introduction Vitamin B12 deficiency gives rise to a wide spectrum of hematological, gastrointestinal, psychiatric, and neurological disorders. Notable among the neuropsychiatric symptoms are mood disturbances, cognitive decline, and psychotic manifes
Externí odkaz:
https://doaj.org/article/fa12b255d46b4ac793aa5893cb20aa73
Publikováno v:
European Psychiatry, Vol 67, Pp S375-S375 (2024)
Introduction Pregnancy and breast-feeding represents a period of psychological maturation for the woman who becomes a mother, a period of significant changes in women’s lives that affects their sexuality and intimacy. Objectives To investigate th
Externí odkaz:
https://doaj.org/article/1727b108f12d42f5a0fffbe027bc060a
Autor:
Mattheus H. E. Wildschut, Julien Mena, Cyril Dördelmann, Marc van Oostrum, Benjamin D. Hale, Jens Settelmeier, Yasmin Festl, Veronika Lysenko, Patrick M. Schürch, Alexander Ring, Yannik Severin, Michael S. Bader, Patrick G. A. Pedrioli, Sandra Goetze, Audrey van Drogen, Stefan Balabanov, Radek C. Skoda, Massimo Lopes, Bernd Wollscheid, Alexandre P. A. Theocharides, Berend Snijder
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Myelofibrosis is a hematopoietic stem cell disorder belonging to the myeloproliferative neoplasms. Myelofibrosis patients frequently carry driver mutations in either JAK2 or Calreticulin (CALR) and have limited therapeutic options. Here, we
Externí odkaz:
https://doaj.org/article/be42116607d44feb831a5d12924ccd1b