Zobrazeno 1 - 10
of 343
pro vyhledávání: '"S, Auld"'
Autor:
Shafqat A. Khan, Kyoung-mi Park, Laura A. Fischer, Chen Dong, Tenzin Lungjangwa, Marta Jimenez, Dominick Casalena, Brian Chew, Sabine Dietmann, Douglas S. Auld, Rudolf Jaenisch, Thorold W. Theunissen
Publikováno v:
Cell Reports, Vol 35, Iss 11, Pp 109233- (2021)
Summary: Naive human embryonic stem cells (hESCs) have been isolated that more closely resemble the pre-implantation epiblast compared to conventional “primed” hESCs, but the signaling principles underlying these discrete stem cell states remain
Externí odkaz:
https://doaj.org/article/0ab0294c046a4f59a6b32af4c1a272a8
Autor:
W. Du, A. Salindri, C. Bryan, M. Kipiani, T. Avaliani, R. Kempker, H. Kornfeld, M. Magee, S. Auld
Publikováno v:
A27. WHITE PLAGUE (TUBERCULOSIS) RESEARCH.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::158c23c5e2f352421904d8649345a78d
https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1211
https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1211
Autor:
Keene L. Abbott, Ahmed Ali, Dominick Casalena, Brian T. Do, Raphael Ferreira, Jaime H. Cheah, Christian K. Soule, Amy Deik, Tenzin Kunchok, Daniel R. Schmidt, Steffen Renner, Sophie E. Honeder, Michelle Wu, Sze Ham Chan, Tenzin Tseyang, Daniel Greaves, Peggy P. Hsu, Christopher W. Ng, Chelsea J. Zhang, Ali Farsidjani, Iva Monique T. Gramatikov, Nicholas J. Matheson, Caroline A. Lewis, Clary B. Clish, Matthew G. Rees, Jennifer A. Roth, Lesley Mathews Griner, Alexander Muir, Douglas S. Auld, Matthew G. Vander Heiden
SUMMARYA challenge for screening new candidate drugs to treat cancer is that efficacy in cell culture models is not always predictive of efficacy in patients. One limitation of standard cell culture is a reliance on non-physiological nutrient levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::121795f51a2d3bf410bf9d8120ac9c3b
https://doi.org/10.1101/2023.02.25.529972
https://doi.org/10.1101/2023.02.25.529972
Autor:
Nathan P. Coussens, Bridget K. Wagner, Douglas S. Auld, Jonathan R. Thielman, Jayme L. Dahlin
Publikováno v:
SLAS Discovery. 26:1280-1290
Compound-dependent assay interferences represent a continued burden in drug and chemical probe discovery. The open-source National Institutes of Health/National Center for Advancing Translational S...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0a96f504b7fb41fd8d913a52068dd68
https://doi.org/10.1177/24725552211026239
https://doi.org/10.1177/24725552211026239
Autor:
Sarine, Markossian, Kyle R, Brimacombe, G Sitta, Sittampalam, Abigail, Grossman, Nathan P, Coussens, James, Inglese, Douglas S, Auld, William, Chin, Christopher P, Austin, Matthew D, Hall
Publikováno v:
Nature reviews. Drug discovery. 21(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c81e7d1bcd68d2a81f64e42abf6154bb
https://pubmed.ncbi.nlm.nih.gov/36253455
https://pubmed.ncbi.nlm.nih.gov/36253455
Akademický článek
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Autor:
J. Willem M. Nissink, Jonathan B. Baell, Francis S. Willard, Ina Rothenaigner, Jonathan Z. Sexton, Douglas S. Auld, Jayme L. Dahlin, John Strelow, Michael A. Walters, Bruce K. Hua, Steve Haney, Lori Ferrins, Jarrod Walsh, Bridget K. Wagner, Jonathan A. Lee, Kamyar Hadian
Publikováno v:
Cell Chem. Bio. 28, 356-370 (2021)
Cell Chem Biol
Cell Chem Biol
Compounds that exhibit assay interference or undesirable mechanisms of bioactivity (“nuisance compounds”) are routinely encountered in cellular assays, including phenotypic and high-content screening assays. Much is known regarding compound-depen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f70a37970ff95ac15de8c8aee188c39
https://doi.org/10.1016/j.chembiol.2021.01.021
https://doi.org/10.1016/j.chembiol.2021.01.021
Autor:
C.S. Calfee, M. Eklund, T.E. Albertson, S. Auld, J.R. Beitler, P.A. Berger, E.L. Burnham, N.K. Cobb, A. Crippa, B.M. Daniel, A. Discacciati, D.C. Files, E.B. Friedman, S. Gandotra, M.N. Gong, K.T. Khan, J.L. Koff, S.I. Kumar, J.E. Lang, R. Lu, T.R. Martin, M.A. Matthay, N.J. Meyer, A. Moskowitz, T.F. Obermiller, P.A. Robinson, D. Russell, K.W. Thomas, S.F. Wong, M.M. Wurfel, R.G. Wunderink, Y.F. Yen, F.A. Youssef, L.J. Esserman, K.D. Liu, null The I-SPY COVID Consortium
Publikováno v:
D94. PANDEMIC OUTPUT: ALL THAT IS COVID-19.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08013e316f5abeffbf2534a2c7c78c64
https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5284
https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5284
Publikováno v:
C106. FIRE TB LIVES ON.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26b7d59399dd5f84ebe9a598589256b1
https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a4936
https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a4936
Autor:
S. Auld, P. Maenetje, N. Mofokeng, J. Daniel, S.B. Montesi, S. Digumarthy, M. Le Fur, P. Caravan, M.-D.-T.W. Vangu, C. Dickens, T. Dix-Peek, C. Tiemessen, D. Schramm, G. Churchyard, R. Wallis, H. Kornfeld, G. Bisson
Publikováno v:
C106. FIRE TB LIVES ON.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db71ca6bfc9e137837f5cc2513666adf
https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a4931
https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a4931