Zobrazeno 1 - 10
of 161
pro vyhledávání: '"S, Anzali"'
Autor:
W W, Mederski, D, Dorsch, M, Osswald, S, Anzali, M, Christadler, C J, Schmitges, P, Schelling, C, Wilm, M, Fluck
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(13)
The discovery, in vitro and in vivo studies of the highly potent ETA antagonist EMD 122946 are presented. This compound displayed high binding affinity and functional antagonism [IC50 = 3.2 x 10(-11) M, pA2 = 9.5 (ETA)] and inhibited the ET-1 induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72da73ed675d2c33b7056c9c602042fa
https://pubmed.ncbi.nlm.nih.gov/9873432
https://pubmed.ncbi.nlm.nih.gov/9873432
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(1)
The methylendioxyphenyl group, present in a number of potent endothelin receptor antagonists, could have undesirable metabolic interactions with cytochrome P450 in vivo. Using a self-organizing neural network we analysed the features of molecular ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3a0103f6d31c7a8070938ab6b424c29e
https://pubmed.ncbi.nlm.nih.gov/9871620
https://pubmed.ncbi.nlm.nih.gov/9871620
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(1)
The methylendioxyphenyl group is present in a number of endothelin receptor antagonists thus far reported. By means of a Kohonen neural network we discovered with a benzothiadiazole a bioisosteric replacement instead. This group should be devoid of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::675a094897a2c9eada9e5012506ba5be
https://pubmed.ncbi.nlm.nih.gov/9871621
https://pubmed.ncbi.nlm.nih.gov/9871621
Autor:
H D, Höltje, S, Anzali
Publikováno v:
Die Pharmazie. 47(9)
Using molecular modelling methods, several digitalis-unlike compounds such as chlormadinol acetate and cassaine, which bind to the digitalis receptor and inhibit the Na+/K(+)-ATPase were compared with cardenolides as a standard. The interaction energ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4034c0395b06ecd3ccb4fc586230210
https://pubmed.ncbi.nlm.nih.gov/1335579
https://pubmed.ncbi.nlm.nih.gov/1335579
Publikováno v:
Sustainability (2071-1050); Dec2024, Vol. 16 Issue 23, p10699, 20p
Autor:
Zhu, Jian‐Xiang1 (AUTHOR), Chen, Zhi‐Chao1 (AUTHOR) chenzhichao@scu.edu.cn, Du, Wei1 (AUTHOR), Chen, Ying‐Chun1,2 (AUTHOR) ycchen@scu.edu.cn
Publikováno v:
Angewandte Chemie. 4/19/2022, Vol. 134 Issue 17, p1-5. 5p.
Autor:
Impastato, Anna C.1 (AUTHOR), Shemet, Andrej1 (AUTHOR), Vepřek, Nynke A.1,2 (AUTHOR), Saper, Gadiel3 (AUTHOR), Hess, Henry3 (AUTHOR), Rao, Lu4 (AUTHOR), Gennerich, Arne4 (AUTHOR) arne.gennerich@einsteinmed.edu, Trauner, Dirk1 (AUTHOR) dirktrauner@nyu.edu
Publikováno v:
Angewandte Chemie. 2/21/2022, Vol. 134 Issue 9, p1-6. 6p.
Autor:
Das S; Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore, 632014, India., Thansila PN; Chemistry Division, School of Advanced Sciences, Vellore Institute of Technology, Chennai, Tamil Nadu, India, 600027., Maiti B; Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore, 632014, India., Padmaja RD; Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore, 632014, India., Prathima TS; Chemistry Division, School of Advanced Sciences, Vellore Institute of Technology, Chennai, Tamil Nadu, India, 600027., Balamurali MM; Chemistry Division, School of Advanced Sciences, Vellore Institute of Technology, Chennai, Tamil Nadu, India, 600027., Chanda K; Department of Chemistry, Rabindranath Tagore University, Hojai, Assam, 782435, India.
Publikováno v:
ChemMedChem [ChemMedChem] 2024 Dec 02; Vol. 19 (23), pp. e202400365. Date of Electronic Publication: 2024 Oct 26.
Autor:
Montejo-López, Wilber, Sampieri-Cabrera, Rául, Nicolás-Vázquez, María Inés, Aceves-Hernández, Juan Manuel, Razo-Hernández, Rodrigo Said
Publikováno v:
RSC Advances; 2024, Vol. 14 Issue 13, p8615-8640, 26p
Publikováno v:
Natural Product Reports; Feb2024, Vol. 41 Issue 2, p208-227, 20p