Zobrazeno 1 - 10 of 103 pro vyhledávání: '"S, Acuto"'
1
Wharton’s Jelly Mesenchymal Stromal Cells Support the Expansion of Cord Blood–derived CD34+Cells Mimicking a Hematopoietic Niche in a Direct Cell–cell Contact Culture System
Autor: Rita Anzalone, Giusi Alberti, Elena Baiamonte, S. Acuto, Giampiero La Rocca, Melania Lo Iacono, Eleonora Russo, Aldo Gerbino, Aurelio Maggio
Publikováno v: Cell Transplantation, Vol 27 (2018)
Cell Transplantation
Wharton’s jelly mesenchymal stromal cells (WJ-MSCs) have been recently exploited as a feeder layer in coculture systems to expand umbilical cord blood–hematopoietic stem/progenitor cells (UCB-HSPCs). Here, we investigated the role of WJ-MSCs in s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc60f36c6c45e8e91f58ea9caf92684
https://doi.org/10.1177/0963689717737089
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2
Akademický článek
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3
Wharton's Jelly Mesenchymal Stromal Cells as a Feeder Layer for the Ex Vivo Expansion of Hematopoietic Stem and Progenitor Cells: a Review
Autor: Giampiero La Rocca, Rita Anzalone, Elena Baiamonte, Aurelio Maggio, Melania Lo Iacono, S. Acuto
In recent years, umbilical cord blood (UCB) has been widely used as an alternative source to bone marrow (BM) for transplantation of hematopoietic stem and progenitor cells (HSPCs) in a variety of hematological and non-hematological disorders. Nevert
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b639e9c1af67f298b6837fc71e452c4
http://hdl.handle.net/10447/245792
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4
The Sea Urchin sns5 Chromatin Insulator Shapes the Chromatin Architecture of a Lentivirus Vector Integrated in the Mammalian Genome
Autor: Aurelio Maggio, Giovanni Spinelli, Elena Baiamonte, Vincenzo Cavalieri, S. Acuto
Publikováno v: Europe PubMed Central
Lentivirus vectors are presently the favorite vehicles for therapeutic gene transfer in hematopoietic cells. Nonetheless, these vectors integrate randomly throughout the genome, exhibiting variegation of transgene expression due to the spreading of h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729acac1403e69e69daace4a039d2411
https://pubmed.ncbi.nlm.nih.gov/27248156
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7
Akademický článek
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8
The Sea Urchin sns5 Insulator Protects Retroviral Vectors From Chromosomal Position Effects by Maintaining Active Chromatin Structure
Autor: Danilo D'Apolito, Leda Ferro, Giovanni Spinelli, Roberta Calzolari, Elena Baiamonte, Mariella Bagliesi, Aurelio Maggio, S. Acuto, Vito Franco, Rosalba Di Marzo
Publikováno v: Molecular Therapy. 17(8):1434-1441
Silencing and position-effect (PE) variegation (PEV), which is due to integration of viral vectors in heterochromatin regions, are considered significant obstacles to obtaining a consistent level of transgene expression in gene therapy. The inclusion
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f0aae5a95421fb4f91e1d70e9fea5b3
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9
Clinical severity of non-deletion form of HbH disease (--Med/ααthal)
Autor: R. Di Marzo, S. Acuto, P. Sammarco, P. Lo Gioco, Antonino Giambona, Aurelio Maggio, G Oddo
Publikováno v: Scandinavian Journal of Haematology. 36:39-43
We carried out alpha-globin gene analysis by restriction endonuclease mapping in a family with 2 cases of HbH disease. These data show that HbH disease in this family results from the interaction between a common deletional defect and a less common n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37588f941a9a77697afb3f609bd3658a
https://doi.org/10.1111/j.1600-0609.1986.tb02647.x
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